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| GeneID |
5923
|
| Symbol |
RASGRF1
|
| Synonyms |
CDC25|CDC25L|GNRP|GRF1|GRF55|H-GRF55|PP13187
|
| Description |
Ras protein-specific guanine nucleotide-releasing factor 1 |
| See related |
HGNC:9875|MIM:606600|Ensembl:ENSG00000058335| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
15q24 |
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| |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 5 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| PAIP2 | 0.86 | 0.87 | | |
| MORF4L2 | 0.85 | 0.86 | | |
| VBP1 | 0.84 | 0.85 | | |
| AZI2 | 0.84 | 0.83 | | |
| ACP1 | 0.84 | 0.83 | | |
| VAPA | 0.84 | 0.83 | | |
| GFM2 | 0.83 | 0.86 | | |
| SCCPDH | 0.83 | 0.81 | | |
| ORC3L | 0.83 | 0.81 | | |
| CAPZA1 | 0.83 | 0.81 | | |
Top 10 negatively co-expressed genes | | AF347015.2 | -0.58 | -0.44 | | |
| AF347015.18 | -0.55 | -0.44 | | |
| AF347015.26 | -0.55 | -0.42 | | |
| AF347015.8 | -0.55 | -0.43 | | |
| MT-CO2 | -0.54 | -0.41 | | |
| AF347015.15 | -0.53 | -0.42 | | |
| MT-CYB | -0.53 | -0.42 | | |
| AF347015.33 | -0.52 | -0.43 | | |
| AF347015.21 | -0.51 | -0.33 | | |
| AF347015.31 | -0.49 | -0.40 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0035254 | glutamate receptor binding | IEA | glutamate (GO term level: 5) | - |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | | - |
| GO:0005085 | guanyl-nucleotide exchange factor activity | IEA | | - |
| GO:0005515 | protein binding | ISS | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0031175 | neurite development | ISS | neuron, axon, neurite, dendrite (GO term level: 10) | - |
| GO:0048168 | regulation of neuronal synaptic plasticity | IEA | neuron, Synap (GO term level: 9) | - |
| GO:0008283 | cell proliferation | IEA | | - |
| GO:0007616 | long-term memory | NAS | | 10918068 |
| GO:0035020 | regulation of Rac protein signal transduction | ISS | | - |
| GO:0035023 | regulation of Rho protein signal transduction | IEA | | - |
| GO:0051056 | regulation of small GTPase mediated signal transduction | IEA | | - |
| GO:0032320 | positive regulation of Ras GTPase activity | ISS | | - |
| GO:0032863 | activation of Rac GTPase activity | ISS | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0019717 | synaptosome | NAS | Synap, Brain (GO term level: 7) | 10918068 |
| GO:0030426 | growth cone | ISS | axon, dendrite (GO term level: 5) | - |
| GO:0005829 | cytosol | ISS | | - |
| GO:0005622 | intracellular | IEA | | - |
| GO:0005886 | plasma membrane | NAS | | 10918068 |
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