Gene Page

Gene Page: PLEKHA1

Summary

GeneID

59338

Symbol

PLEKHA1

Synonyms

TAPP1

Description

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

Locus tag

Gene type

protein-coding

Map location

10q26.13

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.03487

Expression

P value: 1.703

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005543

phospholipid binding

IDA

11001876

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008150

biological_process

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005575

cellular_component

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

GO:0005886

plasma membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
MPDZ	DKFZp781P216 \| FLJ25909 \| FLJ34626 \| FLJ90240 \| MUPP1	multiple PDZ domain protein	-	HPRD,BioGRID	11802782
PLEKHA2	FLJ25921 \| TAPP2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	Two-hybrid	BioGRID	11802782

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-15/16/195/424/497	1548	1555	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-186	179	185	1A	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-21	1772	1779	1A,m8	hsa-miR-21^brain	UAGCUUAUCAGACUGAUGUUGA
miR-21	1772	1779	1A,m8	hsa-miR-590	GAGCUUAUUCAUAAAAGUGCAG
miR-25/32/92/363/367	1060	1067	1A,m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-29	475	481	m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-34b	108	114	m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-9	64	70	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.