Gene Page: ROS1

Summary
GeneID  6098
Symbol  ROS1
Synonyms  MCF3|ROS|c-ros-1
Description  c-ros oncogene 1 , receptor tyrosine kinase
See related  HGNC:10261|MIM:165020|Ensembl:ENSG00000047936|HPRD:01295|
Locus tag  RP1-179P9.1
Gene type  protein-coding
Map location  6q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RPL100.960.96
ERGIC30.960.94
EIF3F0.950.93
RPS50.950.92
SSR20.950.91
GNB2L10.950.92
RPLP0P30.950.93
AKR1A10.940.93
RPL13A0.940.89
RPS4X0.940.94
Top 10 negatively co-expressed genes
AF347015.27-0.62-0.77
APOL1-0.62-0.74
HLA-F-0.61-0.65
AF347015.33-0.60-0.77
AIFM3-0.60-0.64
FBXO2-0.59-0.60
MT-CYB-0.59-0.76
C5orf53-0.59-0.62
APOL3-0.59-0.71
MT-CO2-0.59-0.72
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004714transmembrane receptor protein tyrosine kinase activityIEAneurite (GO term level: 8)-
GO:0000166nucleotide bindingIEA-
GO:0004872receptor activityTAS2827175 
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIEA-
GO:0006468protein amino acid phosphorylationIEA-
GO:0007165signal transductionTAS2827175 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionTAS3785223 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005890sodium:potassium-exchanging ATPase complexTAS3785223 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ABL1ABL | JTK7 | bcr/abl | c-ABL | p150 | v-ablc-abl oncogene 1, receptor tyrosine kinase-HPRD11266449 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Affinity Capture-WesternBioGRID11094073 
PTPN11BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2protein tyrosine phosphatase, non-receptor type 11Two-hybridBioGRID11266449 
PTPN6HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1protein tyrosine phosphatase, non-receptor type 6-HPRD,BioGRID11266449 
VAV3FLJ40431vav 3 guanine nucleotide exchange factor-HPRD,BioGRID11094073 
 


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