Gene Page: BGLAP

Summary
GeneID  632
Symbol  BGLAP
Synonyms  BGP|OC|PMF1
Description  bone gamma-carboxyglutamate (gla) protein
See related  HGNC:1043|MIM:112260|Ensembl:ENSG00000160783|HPRD:00205|
Locus tag  RP11-54H19.5
Gene type  protein-coding
Map location  1q25-q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AGMAT0.620.53
GNA150.620.58
ABCC120.610.59
ATG70.600.54
C6orf1050.590.49
GALNTL50.590.50
AC103681.10.590.57
AC148477.20.580.45
GEFT0.580.55
FHL20.580.50
Top 10 negatively co-expressed genes
PDE9A-0.28-0.35
EIF5B-0.28-0.36
LEMD1-0.28-0.27
PKN1-0.28-0.33
GPR125-0.27-0.25
RNF122-0.27-0.38
LYAR-0.27-0.30
BCL7C-0.26-0.41
UPF3B-0.26-0.32
SH3BP2-0.26-0.33
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0008147structural constituent of boneNAS12467198 
GO:0046848hydroxyapatite bindingNAS10486212 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001501skeletal system developmentTAS10865224 
GO:0007155cell adhesionNAS12202187 
GO:0030500regulation of bone mineralizationIEA-
GO:0042476odontogenesisNAS11856645 
GO:0045124regulation of bone resorptionNAS10486212 
GO:0045670regulation of osteoclast differentiationNAS10486212 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS11856645 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GGCXFLJ26629 | VKCFD1gamma-glutamyl carboxylase-HPRD10393081 
JARID1AKDM5A | RBBP2 | RBP2jumonji, AT rich interactive domain 1ARBP2 interacts with OC promoter.BIND15949438 
RB1OSRC | RB | p105-Rb | pRb | pp110retinoblastoma 1pRB interacts with OC promoter.BIND15949438 
 


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