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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: IKZF4

Summary

GeneID

64375

Symbol

IKZF4

Synonyms

EOS|KIAA1782|ZNFN1A4

Description

IKAROS family zinc finger 4 (Eos)

Locus tag

Gene type

protein-coding

Map location

12q13

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0576

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

TAS

10978333

GO:0008270

zinc ion binding

IEA

GO:0016564

transcription repressor activity

TAS

10978333

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

TAS

10978333

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CHD4	DKFZp686E06161 \| Mi-2b \| Mi2-BETA	chromodomain helicase DNA binding protein 4	-	HPRD,BioGRID	12015313
CTBP1	BARS \| MGC104684	C-terminal binding protein 1	-	HPRD,BioGRID	12444977
HDAC2	RPD3 \| YAF1	histone deacetylase 2	-	HPRD,BioGRID	12015313
HDAC4	HA6116 \| HD4 \| HDAC-A \| HDACA \| KIAA0288	histone deacetylase 4	Affinity Capture-Western	BioGRID	12015313
HDAC5	FLJ90614 \| HD5 \| NY-CO-9	histone deacetylase 5	Affinity Capture-Western	BioGRID	12015313
HDAC7	DKFZp586J0917 \| FLJ99588 \| HD7A \| HDAC7A	histone deacetylase 7	Affinity Capture-Western	BioGRID	12015313
IKZF1	Hs.54452 \| IK1 \| IKAROS \| LYF1 \| PRO0758 \| ZNFN1A1 \| hIk-1	IKAROS family zinc finger 1 (Ikaros)	-	HPRD,BioGRID	10218586 \|10978333
IKZF2	HELIOS \| MGC34330 \| ZNF1A2 \| ZNFN1A2	IKAROS family zinc finger 2 (Helios)	-	HPRD	10978333
IKZF3	AIO \| AIOLOS \| ZNFN1A3	IKAROS family zinc finger 3 (Aiolos)	-	HPRD,BioGRID	10978333
IKZF4	EOS \| KIAA1782 \| ZNFN1A4	IKAROS family zinc finger 4 (Eos)	-	HPRD,BioGRID	10218586 \|10978333
IKZF5	DKFZp781B0249 \| FLJ22973 \| PEGASUS \| ZNFN1A5	IKAROS family zinc finger 5 (Pegasus)	-	HPRD,BioGRID	10978333
NRG1	ARIA \| GGF \| GGF2 \| HGL \| HRG \| HRG1 \| HRGA \| NDF \| SMDF	neuregulin 1	Nrg-1 interacts with Eos. This interaction was modeled on a demonstrated interaction between Nrg-1 from an unspecified species and Eos from an unspecified species.	BIND	15494726
SIN3A	DKFZp434K2235 \| FLJ90319 \| KIAA0700	SIN3 homolog A, transcription regulator (yeast)	Affinity Capture-Western	BioGRID	12015313
SIN3B	KIAA0700	SIN3 homolog B, transcription regulator (yeast)	Affinity Capture-Western	BioGRID	12015313

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	3053	3060	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-101	3053	3060	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-125/351	871	877	m8	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	871	877	m8	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-128	660	666	m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	660	666	m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-130/301	585	592	1A,m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-137	1962	1968	1A	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-144	3040	3046	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-144	3040	3046	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-17-5p/20/93.mr/106/519.d	2406	2413	1A,m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-185	2388	2395	1A,m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
				hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
				hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-216	1540	1546	m8	hsa-miR-216	UAAUCUCAGCUGGCAACUGUG
miR-22	579	585	m8	hsa-miR-22^brain	AAGCUGCCAGUUGAAGAACUGU
miR-25/32/92/363/367	2802	2809	1A,m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-28	396	402	m8	hsa-miR-28^brain	AAGGAGCUCACAGUCUAUUGAG
miR-29	2356	2362	1A	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-365	512	518	1A	hsa-miR-365	UAAUGCCCCUAAAAAUCCUUAU
miR-381	2991	2997	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-504	2416	2422	m8	hsa-miR-504	AGACCCUGGUCUGCACUCUAU
miR-539	2943	2949	1A	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU
miR-9	1550	1556	m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.