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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: SLC6A8

Summary

GeneID

6535

Symbol

SLC6A8

Synonyms

CRT|CRTR|CT1|MGC87396

Description

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

Locus tag

Gene type

protein-coding

Map location

Xq28

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 4

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SVOPL

0.67

0.42

CPXM2

0.66

0.30

VANGL1

0.65

0.47

PAPPA

0.61

0.30

KCND2

0.60

0.57

ARHGAP18

0.59

0.53

RGS8

0.59

0.55

GPR133

0.59

0.44

MYO1B

0.59

0.53

SYT9

0.58

0.34

Top 10 negatively co-expressed genes

AF347015.2

-0.28

-0.45

CXCL14

-0.28

-0.42

OAF

-0.27

-0.43

COX4I2

-0.27

-0.45

HIGD1B

-0.26

-0.46

AF347015.31

-0.26

-0.44

GRIN2C

-0.25

-0.36

MT-CO2

-0.25

-0.44

AF347015.33

-0.25

-0.41

RLBP1

-0.25

-0.43

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005309

creatine:sodium symporter activity

IEA

Neurotransmitter (GO term level: 10)

GO:0005309

creatine:sodium symporter activity

TAS

Neurotransmitter (GO term level: 10)

7953292

GO:0005328

neurotransmitter:sodium symporter activity

IEA

Neurotransmitter (GO term level: 9)

GO:0003674

molecular_function

GO:0015293

symporter activity

IEA

GO:0031402

sodium ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006836

neurotransmitter transport

IEA

neuron, Neurotransmitter (GO term level: 5)

GO:0008150

biological_process

GO:0006814

sodium ion transport

IEA

GO:0006811

ion transport

IEA

GO:0006936

muscle contraction

TAS

8661155

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005575

cellular_component

GO:0016020

membrane

IEA

GO:0005887

integral to plasma membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CD59	16.3A5 \| 1F5 \| EJ16 \| EJ30 \| EL32 \| FLJ38134 \| FLJ92039 \| G344 \| HRF-20 \| HRF20 \| MAC-IP \| MACIF \| MEM43 \| MGC2354 \| MIC11 \| MIN1 \| MIN2 \| MIN3 \| MIRL \| MSK21 \| p18-20	CD59 molecule, complement regulatory protein	-	HPRD	12219031

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-135	34	40	1A	hsa-miR-135a	UAUGGCUUUUUAUUCCUAUGUGA
miR-135	34	40	1A	hsa-miR-135b	UAUGGCUUUUCAUUCCUAUGUG
miR-137	1348	1354	1A	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-138	16	22	m8	hsa-miR-138^brain	AGCUGGUGUUGUGAAUC
miR-149	530	536	m8	hsa-miR-149^brain	UCUGGCUCCGUGUCUUCACUCC
miR-19	707	714	1A,m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	707	714	1A,m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-221/222	1181	1187	1A	hsa-miR-221^brain	AGCUACAUUGUCUGCUGGGUUUC
miR-221/222	1181	1187	1A	hsa-miR-222^brain	AGCUACAUCUGGCUACUGGGUCUC
miR-24*	872	878	1A	hsa-miR-189	GUGCCUACUGAGCUGAUAUCAGU
miR-342	587	593	m8	hsa-miR-342^brain	UCUCACACAGAAAUCGCACCCGUC
miR-377	846	852	1A	hsa-miR-377	AUCACACAAAGGCAACUUUUGU
miR-377	846	852	1A	hsa-miR-377	AUCACACAAAGGCAACUUUUGU
miR-381	747	754	1A,m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.