Gene Page: BMX

Summary
GeneID  660
Symbol  BMX
Synonyms  ETK|PSCTK2|PSCTK3
Description  BMX non-receptor tyrosine kinase
See related  HGNC:1079|MIM:300101|Ensembl:ENSG00000102010|HPRD:02111|
Locus tag  -
Gene type  protein-coding
Map location  Xp22.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.056 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
GHITM0.930.92
GOT10.900.89
ANXA70.890.89
IDH3A0.890.88
GLRB0.880.88
HPRT10.880.87
GDE10.880.89
GABARAPL30.880.89
NRSN10.870.85
MOAP10.870.85
Top 10 negatively co-expressed genes
SH3BP2-0.52-0.53
BCL7C-0.51-0.58
SH2D2A-0.50-0.53
SMTN-0.50-0.53
FAM167B-0.48-0.55
SH2B2-0.48-0.48
ZNF814-0.47-0.53
KIAA1949-0.46-0.32
HYAL2-0.46-0.47
SEMA4B-0.46-0.44
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004871signal transducer activityTAS9520419 
GO:0005515protein bindingIPI16186805 
GO:0005524ATP bindingIEA-
GO:0004715non-membrane spanning protein tyrosine kinase activityIEA-
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationTAS7970727 
GO:0007242intracellular signaling cascadeIEA-
GO:0007498mesoderm developmentTAS9520419 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005813centrosomeIDA18029348 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CASP3CPP32 | CPP32B | SCA-1caspase 3, apoptosis-related cysteine peptidase-HPRD,BioGRID11278797 
CAV1CAV | MSTP085 | VIP21caveolin 1, caveolae protein, 22kDa-HPRD,BioGRID11751885 
PAK1MGC130000 | MGC130001 | PAKalphap21 protein (Cdc42/Rac)-activated kinase 1-HPRD,BioGRID11382770 
PTK2FADK | FAK | FAK1 | pp125FAKPTK2 protein tyrosine kinase 2-HPRD,BioGRID11331870 
PTPN21PTPD1 | PTPRL10protein tyrosine phosphatase, non-receptor type 21-HPRD,BioGRID11013262 
RUFY1FLJ22251 | RABIP4 | ZFYVE12RUN and FYVE domain containing 1Affinity Capture-Western
Biochemical Activity
Two-hybrid		BioGRID11877430 
RUFY2FLJ10063 | KIAA1537 | RABIP4R | ZFYVE13RUN and FYVE domain containing 2Affinity Capture-WesternBioGRID11877430 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)-HPRD,BioGRID10688651 
STAT1DKFZp686B04100 | ISGF-3 | STAT91signal transducer and activator of transcription 1, 91kDa-HPRD9373245 
STAT3APRF | FLJ20882 | HIES | MGC16063signal transducer and activator of transcription 3 (acute-phase response factor)-HPRD,BioGRID10688651 
STAT5AMGF | STAT5signal transducer and activator of transcription 5A-HPRD9373245 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-15/16/195/424/497199205m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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