Gene Page: POLR3D

Summary
GeneID  661
Symbol  POLR3D
Synonyms  BN51T|RPC4|RPC53|TSBN51
Description  polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
See related  HGNC:1080|MIM:187280|Ensembl:ENSG00000168495|HPRD:01755|
Locus tag  -
Gene type  protein-coding
Map location  8q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATF20.950.96
DIS30.940.94
KPNA30.940.96
GSPT10.940.95
CSNK1G30.940.95
IPO70.940.95
FYTTD10.940.96
STAM20.940.94
TBC1D230.940.94
WDR470.940.95
Top 10 negatively co-expressed genes
MT-CO2-0.78-0.84
FXYD1-0.77-0.84
AF347015.31-0.76-0.83
AF347015.8-0.75-0.83
MT-CYB-0.74-0.81
AF347015.33-0.74-0.80
AF347015.27-0.73-0.80
IFI27-0.73-0.80
HSD17B14-0.72-0.77
HIGD1B-0.72-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003899DNA-directed RNA polymerase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006350transcriptionIEA-
GO:0006383transcription from RNA polymerase III promoterIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005666DNA-directed RNA polymerase III complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HSPA8HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71heat shock 70kDa protein 8Affinity Capture-MSBioGRID12391170 
POLR1CRPA39 | RPA40 | RPA5 | RPAC1polymerase (RNA) I polypeptide C, 30kDaAffinity Capture-MSBioGRID12391170 
POLR1DFLJ20616 | MGC9850 | POLR1C | RPA16 | RPA9 | RPAC2 | RPO1-3polymerase (RNA) I polypeptide D, 16kDaAffinity Capture-MSBioGRID12391170 
POLR2ERPABC1 | RPB5 | XAP4 | hRPB25 | hsRPB5polymerase (RNA) II (DNA directed) polypeptide E, 25kDaAffinity Capture-MSBioGRID12391170 
POLR2FHRBP14.4 | POLRF | RPABC2 | RPB14.4 | RPB6polymerase (RNA) II (DNA directed) polypeptide FAffinity Capture-MSBioGRID12391170 
POLR2HRPABC3 | RPB17 | RPB8 | hsRPB8polymerase (RNA) II (DNA directed) polypeptide HAffinity Capture-MSBioGRID12391170 
POLR3ARPC1 | RPC155 | hRPC155polymerase (RNA) III (DNA directed) polypeptide A, 155kDaAffinity Capture-MSBioGRID12391170 
POLR3BFLJ10388 | RPC2polymerase (RNA) III (DNA directed) polypeptide BAffinity Capture-MSBioGRID12391170 
POLR3CRPC3 | RPC62polymerase (RNA) III (DNA directed) polypeptide C (62kD)Affinity Capture-MSBioGRID12391170 
POLR3ERPC5 | SINpolymerase (RNA) III (DNA directed) polypeptide E (80kD)-HPRD,BioGRID12391170 
POLR3FMGC13517 | RPC39 | RPC6polymerase (RNA) III (DNA directed) polypeptide F, 39 kDaAffinity Capture-MSBioGRID12391170 
POLR3GRPC32 | RPC7polymerase (RNA) III (DNA directed) polypeptide G (32kD)Affinity Capture-MSBioGRID12391170 
POLR3HKIAA1665 | MGC111097 | MGC29654 | RPC8polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)Affinity Capture-MSBioGRID12391170 
POLR3KC11 | C11-RNP3 | My010 | RPC10 | RPC11 | hRPC11polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDaAffinity Capture-MSBioGRID12391170 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
let-7/98546552m8hsa-let-7abrainUGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrainUGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrainUGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrainAGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrainUGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrainUGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brainUGAGGUAGUAAGUUGUAUUGUU
hsa-let-7gSZUGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrainUGAGGUAGUAGUUUGUGCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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