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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: SSR1

Summary

GeneID

6745

Symbol

SSR1

Synonyms

DKFZp781N23103|FLJ14232|FLJ22100|FLJ23034|FLJ78242|FLJ93042|TRAPA

Description

signal sequence receptor, alpha

Locus tag

Gene type

protein-coding

Map location

6p24.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0159

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

NDFIP1

0.92

PPP2CA

0.92

0.91

RAB6A

0.90

SRPK2

0.90

0.91

STAU2

0.89

TRUB1

0.89

0.90

DLAT

0.89

RAB2A

0.89

0.87

SLC9A6

0.89

UGCG

0.88

Top 10 negatively co-expressed genes

AF347015.2

-0.63

-0.54

MT-CO2

-0.63

-0.56

FXYD1

-0.62

-0.57

AF347015.26

-0.61

-0.53

EIF4EBP3

-0.61

-0.64

HIGD1B

-0.61

-0.55

AP002478.3

-0.61

-0.62

AF347015.33

-0.60

-0.53

AF347015.31

-0.60

-0.54

AF347015.8

-0.60

-0.55

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005048

signal sequence binding

TAS

8050590

GO:0005509

calcium ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008284

positive regulation of cell proliferation

TAS

10437777

GO:0006613

cotranslational protein targeting to membrane

TAS

8050590

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005789

endoplasmic reticulum membrane

IEA

GO:0005783

endoplasmic reticulum

TAS

8050590

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

TAS

8050590

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DKC1	CBF5 \| DKC \| FLJ97620 \| NAP57 \| NOLA4 \| XAP101 \| dyskerin	dyskeratosis congenita 1, dyskerin	Two-hybrid	BioGRID	16169070
EEF1A1	CCS-3 \| CCS3 \| EEF-1 \| EEF1A \| EF-Tu \| EF1A \| FLJ25721 \| GRAF-1EF \| HNGC:16303 \| LENG7 \| MGC102687 \| MGC131894 \| MGC16224 \| PTI1 \| eEF1A-1	eukaryotic translation elongation factor 1 alpha 1	Two-hybrid	BioGRID	16169070
NUP54	MGC13407	nucleoporin 54kDa	-	HPRD	8707840
PTN	HARP \| HBGF8 \| HBNF \| NEGF1	pleiotrophin	Two-hybrid	BioGRID	16169070
UTP14A	KIAA0266 \| NY-CO-16 \| SDCCAG16 \| dJ537K23.3	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	Two-hybrid	BioGRID	16169070

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-135	1233	1240	1A,m8	hsa-miR-135a	UAUGGCUUUUUAUUCCUAUGUGA
miR-135	1233	1240	1A,m8	hsa-miR-135b	UAUGGCUUUUCAUUCCUAUGUG
miR-148/152	159	165	m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-196	274	280	m8	hsa-miR-196a	UAGGUAGUUUCAUGUUGUUGG
miR-196	274	280	m8	hsa-miR-196b	UAGGUAGUUUCCUGUUGUUGG
miR-218	2066	2072	m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-30-3p	152	158	1A	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	152	158	1A	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-495	2058	2064	m8	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-496	2110	2116	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-544	2014	2020	1A	hsa-miR-544	AUUCUGCAUUUUUAGCAAGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.