Gene Page: SSR2

Summary
GeneID  6746
Symbol  SSR2
Synonyms  DKFZp686F19123|HSD25|TLAP|TRAP-BETA|TRAPB
Description  signal sequence receptor, beta (translocon-associated protein beta)
See related  HGNC:11324|MIM:600867|Ensembl:ENSG00000163479|HPRD:02923|
Locus tag  -
Gene type  protein-coding
Map location  1q21-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ACTN10.930.86
NPTN0.920.88
SMAD30.910.90
PACSIN10.910.86
PTPRN0.910.86
SLC35F30.900.88
AC105206.10.900.87
MAST30.900.91
SAPS10.900.89
TMEM1300.900.89
Top 10 negatively co-expressed genes
BCL7C-0.52-0.61
RBMX2-0.50-0.57
C9orf46-0.49-0.53
RPS8-0.48-0.56
EXOSC8-0.48-0.49
FAM36A-0.48-0.44
RPS19P3-0.48-0.60
RPL27A-0.47-0.61
RPS23-0.47-0.53
RPL38-0.47-0.64
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005048signal sequence bindingTAS7789174 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006613cotranslational protein targeting to membraneTAS7789174 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0005783endoplasmic reticulumTAS7789174 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0016021integral to membraneTAS7789174 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SRPRDP | MGC17355 | MGC3650 | MGC9571 | SRP-alpha | Sralphasignal recognition particle receptor (docking protein)-HPRD,BioGRID3021779 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1352062131A,m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.