Gene Page: VAMP7

Summary
GeneID  6845
Symbol  VAMP7
Synonyms  SYBL1|TI-VAMP|VAMP-7
Description  vesicle-associated membrane protein 7
See related  HGNC:11486|MIM:300053|Ensembl:ENSG00000124333|HPRD:02084|
Locus tag  -
Gene type  protein-coding
Map location  Xq28 and Yq12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AP1G10.940.95
WDR260.940.95
C4orf410.940.94
NUP500.940.94
RAD23B0.930.93
FAF20.930.93
FBXO380.930.94
ZC3H140.930.94
RABGEF10.930.93
CUL10.930.93
Top 10 negatively co-expressed genes
FXYD1-0.80-0.84
MT-CO2-0.80-0.84
AF347015.31-0.80-0.83
HIGD1B-0.78-0.83
IFI27-0.77-0.82
AF347015.33-0.77-0.79
MT-CYB-0.76-0.80
AF347015.21-0.76-0.82
AF347015.8-0.76-0.82
AF347015.27-0.74-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingISS14993220 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008333endosome to lysosome transportIDA10888671 
GO:0006911phagocytosis, engulfmentISS15133481 
GO:0006906vesicle fusionIDA10888671 
GO:0006888ER to Golgi vesicle-mediated transportISS16495485 
GO:0043308eosinophil degranulationISS14993220 
GO:0015031protein transportIEA-
GO:0043312neutrophil degranulationISS14993220 
GO:0017156calcium ion-dependent exocytosisISS14993220 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0031201SNARE complexISSneuron, Synap (GO term level: 6)15133481 
GO:0005794Golgi apparatusIEA-
GO:0005789endoplasmic reticulum membraneISS16495485 
GO:0005765lysosomal membraneISS10459012 
GO:0005768endosomeIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0031410cytoplasmic vesicleIEA-
GO:0031902late endosome membraneISS10459012 
GO:0045335phagocytic vesicleISS15470500 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP3D1ADTD | hBLVRadaptor-related protein complex 3, delta 1 subunit-HPRD,BioGRID12853575 
AP3M1MGC22164adaptor-related protein complex 3, mu 1 subunitAffinity Capture-WesternBioGRID12853575 
DNAJC5CSP | DKFZp434N1429 | DKFZp761N1221 | DNAJC5A | FLJ00118 | FLJ13070DnaJ (Hsp40) homolog, subfamily C, member 5Csp1 interacts with VAMP7. This interaction was modeled on a demonstrated interaction between cow Csp1, and human VAMP7.BIND15610015 
SNAP23HsT17016 | SNAP23A | SNAP23Bsynaptosomal-associated protein, 23kDaSNAP23 interacts with VAMP7.BIND15610015 
-HPRD,BioGRID9614185 
SNAP25FLJ23079 | RIC-4 | RIC4 | SEC9 | SNAP | SNAP-25 | bA416N4.2 | dJ1068F16.2synaptosomal-associated protein, 25kDa-HPRD,BioGRID12853575 
SNAP29CEDNIK | FLJ21051 | SNAP-29synaptosomal-associated protein, 29kDa-HPRD,BioGRID12853575 
STX1AHPC-1 | STX1 | p35-1syntaxin 1A (brain)-HPRD,BioGRID12853575 
STX3STX3Asyntaxin 3-HPRD9614185 
STX4STX4A | p35-2syntaxin 4Affinity Capture-WesternBioGRID12853575 
STX7-syntaxin 7in vitro
in vivo		BioGRID11278762 |12175335 
-HPRD11278762|12175335 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/50613531359m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1433974031Ahsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-15/16/195/424/497496502m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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