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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: SYT4

Summary

GeneID

6860

Symbol

SYT4

Synonyms

HsT1192|KIAA1342

Description

synaptotagmin IV

Locus tag

Gene type

protein-coding

Map location

18q12.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 3

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

NPC1

0.91

0.84

ABCA2

0.91

0.82

USP54

0.91

0.87

MYO1D

0.91

0.90

C11orf9

0.90

0.63

SEMA4D

0.89

0.79

PCSK6

0.89

0.76

SLC31A2

0.88

0.73

MAN2A2

0.88

0.86

UNC5B

0.87

0.81

Top 10 negatively co-expressed genes

ST20

-0.47

-0.62

PFDN5

-0.42

-0.49

AC006276.2

-0.41

-0.47

C9orf46

-0.41

-0.45

COX16

-0.41

-0.47

RPL35

-0.41

-0.51

RPL31

-0.41

-0.52

RPL12

-0.39

-0.45

C8orf59

-0.39

-0.47

FAM36A

-0.39

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005509

calcium ion binding

IEA

GO:0005215

transporter activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007269

neurotransmitter secretion

IEA

neuron, axon, Synap, serotonin, Neurotransmitter, dopamine (GO term level: 8)

GO:0006810

transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008021

synaptic vesicle

IEA

Synap, Neurotransmitter (GO term level: 12)

GO:0043005

neuron projection

IEA

neuron, axon, neurite, dendrite (GO term level: 5)

GO:0045202

synapse

IEA

neuron, Synap, Neurotransmitter, Glial (GO term level: 2)

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

GO:0048471

perinuclear region of cytoplasm

IEA

GO:0030054

cell junction

IEA

GO:0031410

cytoplasmic vesicle

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
NRXN1	DKFZp313P2036 \| FLJ35941 \| Hs.22998 \| KIAA0578	neurexin 1	-	HPRD	8901523
SGTA	SGT \| alphaSGT \| hSGT	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	Two-hybrid	BioGRID	16189514
STX1A	HPC-1 \| STX1 \| p35-1	syntaxin 1A (brain)	-	HPRD	10397765
STX2	EPIM \| EPM \| MGC51014 \| STX2A \| STX2B \| STX2C	syntaxin 2	-	HPRD	10397765
STX3	STX3A	syntaxin 3	-	HPRD	10397765
STX4	STX4A \| p35-2	syntaxin 4	-	HPRD	10397765
SYNCRIP	GRY-RBP \| HNRPQ1 \| NSAP1 \| RP1-3J17.2 \| dJ3J17.2 \| hnRNP-Q \| pp68	synaptotagmin binding, cytoplasmic RNA interacting protein	-	HPRD,BioGRID	10734137
SYT1	DKFZp781D2042 \| P65 \| SVP65 \| SYT	synaptotagmin I	-	HPRD	10397765
SYT4	HsT1192 \| KIAA1342	synaptotagmin IV	-	HPRD	10397765
TFAP2B	AP-2B \| AP2-B \| MGC21381	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	-	HPRD	7993622

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-128	640	646	m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	640	646	m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-141/200a	1475	1481	m8	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	1475	1481	m8	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-30-3p	2134	2140	1A	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	2134	2140	1A	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-34/449	740	746	m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-493-5p	1572	1579	1A,m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-9	435	441	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.