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|
| GeneID |
7051
|
| Symbol |
TGM1
|
| Synonyms |
ICR2|KTG|LI|LI1|TGASE|TGK
|
| Description |
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) |
| See related |
HGNC:11777|MIM:190195|Ensembl:ENSG00000092295|HPRD:01824| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
14q11.2 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.047 | |
|
| |
| General Gene Expression (microarray) ? |
|
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| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| FYCO1 | 0.87 | 0.89 | | |
| DOCK1 | 0.87 | 0.86 | | |
| ARHGEF10 | 0.86 | 0.85 | | |
| MYO10 | 0.85 | 0.85 | | |
| PHLPP1 | 0.84 | 0.84 | | |
| FGFR2 | 0.83 | 0.80 | | |
| TJP1 | 0.83 | 0.81 | | |
| TNS1 | 0.82 | 0.85 | | |
| RRBP1 | 0.82 | 0.84 | | |
| SNX33 | 0.81 | 0.84 | | |
Top 10 negatively co-expressed genes | | NDUFAF2 | -0.54 | -0.61 | | |
| ZNF32 | -0.54 | -0.61 | | |
| PFDN5 | -0.53 | -0.61 | | |
| VPS29 | -0.52 | -0.57 | | |
| PSMA6 | -0.52 | -0.60 | | |
| ST20 | -0.52 | -0.61 | | |
| PPP2R3C | -0.51 | -0.57 | | |
| COMMD3 | -0.51 | -0.56 | | |
| PFDN4 | -0.51 | -0.62 | | |
| GTF3A | -0.51 | -0.57 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0003810 | protein-glutamine gamma-glutamyltransferase activity | IDA | | 7961731 |
| GO:0005509 | calcium ion binding | IEA | | - |
| GO:0005515 | protein binding | IPI | | 7592852 |9722562 |10066784
|10510474 |
| GO:0016740 | transferase activity | IEA | | - |
| GO:0008415 | acyltransferase activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006464 | protein modification process | NAS | | 1979171 |
| GO:0009887 | organ morphogenesis | IEA | | - |
| GO:0018149 | peptide cross-linking | IEA | | - |
| GO:0030216 | keratinocyte differentiation | IDA | | 8824274 |
| GO:0031424 | keratinization | IEA | | - |
| GO:0043163 | cell envelope organization | TAS | | 14645372 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001533 | cornified envelope | TAS | | 8824274 |
| GO:0016020 | membrane | IEA | | - |
| GO:0005913 | cell-cell adherens junction | IEA | | - |
| GO:0031224 | intrinsic to membrane | IDA | | 8824274 |
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