Gene Page: TH

Summary
GeneID  7054
Symbol  TH
Synonyms  TYH
Description  tyrosine hydroxylase
See related  HGNC:11782|MIM:191290|Ensembl:ENSG00000180176|HPRD:01865|
Locus tag  -
Gene type  protein-coding
Map location  11p15.5
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias, schizophrenics]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0004497monooxygenase activityIEA-
GO:0004511tyrosine 3-monooxygenase activityIDA16338639 
GO:0004511tyrosine 3-monooxygenase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007268synaptic transmissionIEAneuron, Synap, Neurotransmitter (GO term level: 6)-
GO:0006585dopamine biosynthetic process from tyrosineIEANeurotransmitter, dopamine (GO term level: 10)-
GO:0001963synaptic transmission, dopaminergicIEAneuron, Synap, Neurotransmitter, dopamine (GO term level: 8)-
GO:0042136neurotransmitter biosynthetic processIEAneuron, axon, Synap, Neurotransmitter (GO term level: 9)-
GO:0009072aromatic amino acid family metabolic processIEA-
GO:0009887organ morphogenesisIEA-
GO:0009653anatomical structure morphogenesisTAS7715703 
GO:0007507heart developmentIEA-
GO:0008016regulation of heart contractionIEA-
GO:0007626locomotory behaviorIEA-
GO:0007617mating behaviorIEA-
GO:0007612learningIEA-
GO:0007613memoryIEA-
GO:0042755eating behaviorIEA-
GO:0042423catecholamine biosynthetic processIEA-
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIDA10907721 
GO:0005737cytoplasmIEA-
GO:0043204perikaryonIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1Biochemical ActivityBioGRID1347949 
MAPK3ERK1 | HS44KDAP | HUMKER1A | MGC20180 | P44ERK1 | P44MAPK | PRKM3mitogen-activated protein kinase 3-HPRD,BioGRID1347949 
SNCAMGC110988 | NACP | PARK1 | PARK4 | PD1synuclein, alpha (non A4 component of amyloid precursor)-HPRD11943812 
YWHAZKCIP-1 | MGC111427 | MGC126532 | MGC138156tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide-HPRD11359875 
 


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.