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| GeneID |
7166
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| Symbol |
TPH1
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| Synonyms |
MGC119994|TPH|TPRH
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| Description |
tryptophan hydroxylase 1 |
| See related |
HGNC:12008|MIM:191060|Ensembl:ENSG00000129167|HPRD:01846| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
11p15.3-p14 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Association | A combined odds ratio method (Sun et al. 2008), association studies | 2 | Link to SZGene | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 31 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
Top 10 negatively co-expressed genes | |
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005506 | iron ion binding | IEA | | - |
| GO:0004497 | monooxygenase activity | IEA | | - |
| GO:0004510 | tryptophan 5-monooxygenase activity | IEA | | - |
| GO:0016597 | amino acid binding | IEA | | - |
| GO:0046872 | metal ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006587 | serotonin biosynthetic process from tryptophan | IEA | serotonin, Neurotransmitter (GO term level: 10) | - |
| GO:0009072 | aromatic amino acid family metabolic process | IEA | | - |
| GO:0008152 | metabolic process | IEA | | - |
| GO:0055114 | oxidation reduction | IEA | | - |
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