Gene Page: TRPC5

Summary
GeneID  7224
Symbol  TRPC5
Synonyms  TRP5
Description  transient receptor potential cation channel, subfamily C, member 5
See related  HGNC:12337|MIM:300334|Ensembl:ENSG00000072315|HPRD:02273|
Locus tag  RP1-68D15.2
Gene type  protein-coding
Map location  Xq23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
WHSC1L10.950.97
RBM160.950.97
HP1BP30.950.96
C6orf1740.950.97
NSD10.950.95
MED10.950.96
SETD20.940.96
ZNF8280.940.96
TOPBP10.940.97
LATS10.940.96
Top 10 negatively co-expressed genes
AF347015.31-0.78-0.89
FXYD1-0.78-0.89
MT-CO2-0.77-0.90
AF347015.27-0.76-0.87
HSD17B14-0.76-0.83
AIFM3-0.76-0.79
TSC22D4-0.76-0.82
AF347015.33-0.75-0.86
IFI27-0.75-0.88
S100B-0.75-0.84
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003735structural constituent of ribosomeIEA-
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIPI15757897 
GO:0005216ion channel activityIEA-
GO:0015279store-operated calcium channel activityTAS10493832 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)10493832 
GO:0006412translationIEA-
GO:0006816calcium ion transportTAS10493832 
GO:0006811ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005840ribosomeIEA-
GO:0005622intracellularIEA-
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS10493832 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HOMER1HOMER | HOMER1A | HOMER1B | HOMER1C | SYN47 | Ves-1homer homolog 1 (Drosophila)Affinity Capture-WesternBioGRID14505576 
HOMER3HOMER-3homer homolog 3 (Drosophila)Affinity Capture-WesternBioGRID14505576 
ITPR1INSP3R1 | IP3R | IP3R1 | SCA15 | SCA16inositol 1,4,5-triphosphate receptor, type 1Affinity Capture-WesternBioGRID14505576 
ITPR3FLJ36205 | IP3R | IP3R3inositol 1,4,5-triphosphate receptor, type 3-HPRD,BioGRID11290752 
MX1IFI-78K | IFI78 | MX | MxAmyxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)MxA interacts with TRPC5. This interaction was modeled on a demonstrated interaction between human MxA and TRPC5 from unspecified species.BIND15757897 
SLC9A3R1EBP50 | NHERF | NHERF1 | NPHLOP2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1-HPRD10980202 
STMN1LAP18 | Lag | OP18 | PP17 | PP19 | PR22 | SMNstathmin 1/oncoprotein 18Affinity Capture-WesternBioGRID12858178 
STMN2SCG10 | SCGN10 | SGC10stathmin-like 2Affinity Capture-WesternBioGRID12858178 
STMN3SCLIPstathmin-like 3Reconstituted Complex
Two-hybrid		BioGRID12858178 
STMN4MGC111012 | RB3stathmin-like 4Affinity Capture-WesternBioGRID12858178 
TRPC1HTRP-1 | MGC133334 | MGC133335 | TRP1transient receptor potential cation channel, subfamily C, member 1-HPRD,BioGRID11301024 
-HPRD12032305 |12857742 
TRPC3TRP3transient receptor potential cation channel, subfamily C, member 3Affinity Capture-WesternBioGRID12857742 
TRPC4HTRP4 | MGC119570 | MGC119571 | MGC119572 | MGC119573 | TRP4transient receptor potential cation channel, subfamily C, member 4Affinity Capture-Western
FRET		BioGRID12032305 
TRPC5TRP5transient receptor potential cation channel, subfamily C, member 5-HPRD12032305 
TRPC6FLJ11098 | FLJ14863 | FSGS2 | TRP6transient receptor potential cation channel, subfamily C, member 6Affinity Capture-WesternBioGRID12857742 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-204/211517523m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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