Gene Page

Gene Page: UBE2E1

Summary

GeneID

7324

Symbol

UBE2E1

Synonyms

UBCH6

Description

ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)

Locus tag

Gene type

protein-coding

Map location

3p24.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.006

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

14667819

GO:0004842

ubiquitin-protein ligase activity

TAS

8576257

GO:0016874

ligase activity

IEA

GO:0042296

ISG15 ligase activity

IDA

16428300

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006511

ubiquitin-dependent protein catabolic process

TAS

8576257

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

EXP

11285280

GO:0051246

regulation of protein metabolic process

IEA

GO:0032020

ISG15-protein conjugation

IDA

16428300

GO:0051436

negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle

EXP

14593737 |15029244

GO:0051437

positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle

EXP

10793135

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

EXP

10793135 |11285280 |11535616
|11742988 |12070128

GO:0005654

nucleoplasm

EXP

10548110 |11340163 |15029244

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CBWD5	DC36 \| FLJ34856 \| FLJ40320 \| FLJ77192 \| MGC167043 \| MGC44166	COBW domain containing 5	Two-hybrid	BioGRID	16169070
NEDD4	KIAA0093 \| MGC176705 \| NEDD4-1 \| RPF1	neural precursor cell expressed, developmentally down-regulated 4	-	HPRD,BioGRID	9990509
NEDD4L	FLJ33870 \| KIAA0439 \| NEDD4-2 \| RSP5 \| hNedd4-2	neural precursor cell expressed, developmentally down-regulated 4-like	-	HPRD	8576257
PAEP	GD \| GdA \| GdF \| GdS \| MGC138509 \| MGC142288 \| PAEG \| PEP \| PP14	progestagen-associated endometrial protein	Two-hybrid	BioGRID	16169070
RNF14	ARA54 \| FLJ26004 \| HFB30 \| HRIHFB2038 \| TRIAD2	ring finger protein 14	-	HPRD,BioGRID	11322894
RNF8	FLJ12013 \| KIAA0646	ring finger protein 8	-	HPRD,BioGRID	11322894
UBE2G1	E217K \| UBC7 \| UBE2G	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	-	HPRD,BioGRID	8393731
UBE3A	ANCR \| AS \| E6-AP \| EPVE6AP \| FLJ26981 \| HPVE6A	ubiquitin protein ligase E3A	-	HPRD	8576257
UBOX5	KIAA0860 \| RNF37 \| UBCE7IP5 \| UIP5	U-box domain containing 5	-	HPRD	11274149

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-496	337	343	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-499	124	130	m8	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA
miR-542-3p	32	39	1A,m8	hsa-miR-542-3p	UGUGACAGAUUGAUAACUGAAA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.