Gene Page: UCHL3

Summary
GeneID  7347
Symbol  UCHL3
Synonyms  UCH-L3
Description  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
See related  HGNC:12515|MIM:603090|Ensembl:ENSG00000118939|HPRD:04367|
Locus tag  RP11-173B14.3
Gene type  protein-coding
Map location  13q22.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MGST30.850.83
SEPW10.840.82
NDUFS30.840.80
COX170.840.78
RPS19BP10.830.81
MECR0.830.87
NDUFA130.830.76
GUK10.830.77
COX5B0.820.81
ITGB1BP10.820.72
Top 10 negatively co-expressed genes
MAP4K4-0.50-0.56
SMTN-0.49-0.65
ANKHD1-0.48-0.48
AC005035.1-0.47-0.54
THOC2-0.46-0.51
HIP1R-0.46-0.50
ZNF652-0.45-0.44
KIAA0355-0.45-0.41
MYO9B-0.44-0.48
KIAA0323-0.44-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004221ubiquitin thiolesterase activityTAS2530630 
GO:0008234cysteine-type peptidase activityIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006511ubiquitin-dependent protein catabolic processNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005737cytoplasmNAS-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NEDD8FLJ43224 | MGC104393 | MGC125896 | MGC125897 | Nedd-8neural precursor cell expressed, developmentally down-regulated 8-HPRD,BioGRID9790970 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-5p105111m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-18354601Ahsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-369-3p2935m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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