Gene Page: RDBP

Summary
GeneID  7936
Symbol  RDBP
Synonyms  D6S45|NELF-E|RD|RDP
Description  RD RNA binding protein
See related  HGNC:13974|MIM:154040|Ensembl:ENSG00000204356|HPRD:01096|
Locus tag  DADB-122G4.4
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TEX100.950.92
POLR1E0.940.88
NUP880.930.91
APEX10.930.92
IGBP10.930.91
RPL40.930.91
RFWD20.930.92
EFTUD10.920.86
EIF3D0.920.89
EIF3L0.920.93
Top 10 negatively co-expressed genes
HLA-F-0.71-0.78
AF347015.27-0.70-0.86
AF347015.33-0.69-0.87
AIFM3-0.69-0.75
MT-CO2-0.68-0.85
AF347015.31-0.68-0.83
AF347015.8-0.67-0.87
MT-CYB-0.67-0.85
TINAGL1-0.66-0.75
HEPN1-0.66-0.73
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingNAS2119325 
GO:0005515protein bindingIPI14667819 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0008150biological_processND-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusNAS2119325 
GO:0005654nucleoplasmEXP12676794 
GO:0005730nucleolusIDA18029348 
GO:0005739mitochondrionIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C19orf29NY-REN-24 | cactin | fSAPcchromosome 19 open reading frame 29Two-hybridBioGRID14667819 
COBRA1DKFZp586B0519 | KIAA1182 | NELF-B | NELFBcofactor of BRCA1-HPRD,BioGRID10199401 |12612062 
|14667819 |15342491 
NCOR1KIAA1047 | MGC104216 | N-CoR | TRAC1 | hCIT529I10 | hN-CoRnuclear receptor co-repressor 1Two-hybridBioGRID14667819 
POLR2AMGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1polymerase (RNA) II (DNA directed) polypeptide A, 220kDaAffinity Capture-WesternBioGRID12612062 
TH1LHSPC130 | NELF-C | NELF-D | TH1TH1-like (Drosophila)Affinity Capture-MS
Affinity Capture-Western
Reconstituted Complex		BioGRID12612062 |17353931 
VAMP3CEBvesicle-associated membrane protein 3 (cellubrevin)Two-hybridBioGRID16169070 
WHSC2FLJ10442 | FLJ25112 | NELF-A | NELFA | P/OKcl.15Wolf-Hirschhorn syndrome candidate 2Affinity Capture-MS
Affinity Capture-Western
Reconstituted Complex		BioGRID12612062 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-485-5p8591m8hsa-miR-485-5pAGAGGCUGGCCGUGAUGAAUUC
miR-93.hd/291-3p/294/295/302/372/373/520101107m8hsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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