Gene Page: SAP130

Summary
GeneID  79595
Symbol  SAP130
Synonyms  FLJ12761
Description  Sin3A-associated protein, 130kDa
See related  HGNC:29813|MIM:609697|Ensembl:ENSG00000136715|HPRD:18015|
Locus tag  -
Gene type  protein-coding
Map location  2q14.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.023 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TNFAIP20.620.51
AC079061.10.610.58
PKHD1L10.600.33
RASGEF1C0.570.58
ACTA10.560.53
PTPRK0.560.54
SMPDL3A0.550.53
LRRN30.550.50
RBM240.550.55
LRFN20.550.59
Top 10 negatively co-expressed genes
ACSF2-0.38-0.42
C11orf67-0.38-0.42
MICA-0.37-0.41
MT-CO2-0.36-0.34
AF347015.8-0.35-0.33
NSBP1-0.35-0.43
SORBS3-0.35-0.33
AF347015.33-0.35-0.31
MT-CYB-0.35-0.32
TRIP6-0.34-0.37
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004339glucan 1,4-alpha-glucosidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARID4BBCAA | BRCAA1 | DKFZp313M2420 | MGC163290 | RBBP1L1 | RBP1L1 | SAP180AT rich interactive domain 4B (RBP1-like)-HPRD,BioGRID12724404 
HDAC1DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1histone deacetylase 1Affinity Capture-WesternBioGRID12724404 
HDAC2RPD3 | YAF1histone deacetylase 2Affinity Capture-WesternBioGRID12724404 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)Co-purification
Reconstituted Complex		BioGRID12660246 
SIN3ADKFZp434K2235 | FLJ90319 | KIAA0700SIN3 homolog A, transcription regulator (yeast)Affinity Capture-MS
Affinity Capture-Western		BioGRID12724404 
SUDS3FLJ00052 | MGC104711 | SAP45 | SDS3suppressor of defective silencing 3 homolog (S. cerevisiae)Affinity Capture-WesternBioGRID12724404 
SUPT3HSPT3 | SPT3Lsuppressor of Ty 3 homolog (S. cerevisiae)Affinity Capture-WesternBioGRID11406595 
TAF4FLJ41943 | TAF2C | TAF2C1 | TAF4A | TAFII130 | TAFII135TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDaAffinity Capture-WesternBioGRID11406595 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-24359365m8hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-30-3p369375m8hsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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