Gene Page: ITFG1

Summary ?
GeneID81533
SymbolITFG1
Synonyms2310047C21Rik|CDA08|LNKN-1|TIP
Descriptionintegrin alpha FG-GAP repeat containing 1
ReferenceMIM:611803|HGNC:HGNC:30697|Ensembl:ENSG00000129636|HPRD:16692|Vega:OTTHUMG00000133103
Gene typeprotein-coding
Map location16q12.1
Pascal p-value0.021
eGeneCaudate basal ganglia
Myers' cis & trans
SupportG2Cdb.humanPSD
G2Cdb.humanPSP

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IIEGenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs823066chr1205771172ITFG1815330.01trans
rs2716734chr239947720ITFG1815330.01trans
rs2716736chr239947946ITFG1815330.01trans
rs16837822chr2155406624ITFG1815330.19trans
rs16837825chr2155407056ITFG1815330.19trans
rs6729327chr2215397001ITFG1815330.14trans
rs16869878chr52523760ITFG1815330.13trans
rs467856chr53128168ITFG1815330.04trans
snp_a-21696230ITFG1815330.08trans
rs13175086chr5174691428ITFG1815332.566E-5trans
rs10079090chr5174718575ITFG1815330.08trans
rs2016128chr642442743ITFG1815330.13trans
rs4947631chr750603378ITFG1815330.07trans
rs17085704chr985297313ITFG1815330.13trans
rs16918008chr9101655002ITFG1815330.06trans
rs7298298chr1217810638ITFG1815330.16trans
rs9590075chr1395414389ITFG1815330.14trans
rs6128541chr2057917688ITFG1815330.12trans
rs225434chr2143724740ITFG1815330.07trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 DN 391222All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS UP 306188All SZGR 2.0 genes in this pathway
ROYLANCE BREAST CANCER 16Q COPY NUMBER DN 2619All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 3 4WK UP 214144All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584356All SZGR 2.0 genes in this pathway
LIANG HEMATOPOIESIS STEM CELL NUMBER SMALL VS HUGE UP 3829All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS UP 424268All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN 10364All SZGR 2.0 genes in this pathway
GOLDRATH HOMEOSTATIC PROLIFERATION 171102All SZGR 2.0 genes in this pathway
MCCLUNG COCAINE REWARD 5D 7962All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973570All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP A 898516All SZGR 2.0 genes in this pathway