Gene Page

Gene Page: DIAPH3

Summary

GeneID

81624

Symbol

DIAPH3

Synonyms

DKFZp434C0931|DKFZp686A13178|DRF3|Dia2|FLJ34705|diap3

Description

diaphanous homolog 3 (Drosophila)

Locus tag

RP11-26P21.1

Gene type

protein-coding

Map location

13q21.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SUSD2

0.89

0.41

RGS16

0.88

0.25

CHRNA3

0.86

0.06

CARD11

0.86

0.28

FAM180B

0.85

0.12

RDH12

0.85

0.32

FAM20A

0.85

0.23

TTC39A

0.85

0.24

PAPPA

0.83

0.18

GRID2IP

0.82

0.11

Top 10 negatively co-expressed genes

MEIS3P2

-0.24

-0.16

PLEKHO1

-0.23

-0.27

CACNB3

-0.22

-0.13

ZNF184

-0.21

-0.20

WDR86

-0.20

-0.07

NR2C2AP

-0.19

-0.26

GPM6A

-0.19

-0.24

METTL10

-0.19

-0.22

PLK2

-0.19

-0.23

SSBP4

-0.19

-0.03

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003779

actin binding

IEA

GO:0017048

Rho GTPase binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016043

cellular component organization

IEA

GO:0030036

actin cytoskeleton organization

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
NCKIPSD	AF3P21 \| DIP \| DIP1 \| MGC23891 \| ORF1 \| SPIN90 \| WASLBP \| WISH	NCK interacting protein with SH3 domain	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	11509578

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	923	929	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-130/301	982	989	1A,m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-142-5p	91	98	1A,m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-219	853	860	1A,m8	hsa-miR-219^brain	UGAUUGUCCAAACGCAAUUCU
miR-224	88	94	m8	hsa-miR-224	CAAGUCACUAGUGGUUCCGUUUA
miR-26	63	69	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	63	69	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-410	94	100	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.