Gene Page: HIST1H4G
Summary ?
| GeneID | 8369 |
| Symbol | HIST1H4G |
| Synonyms | H4/l|H4FL |
| Description | histone cluster 1, H4g |
| Reference | MIM:602832|HGNC:HGNC:4792|Ensembl:ENSG00000275663|HPRD:11806|Vega:OTTHUMG00000014444 |
| Gene type | protein-coding |
| Map location | 6p22.2 |
| Pascal p-value | 9.949E-4 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| GSMA_I | Genome scan meta-analysis | Psr: 0.033 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PDHX | 0.88 | 0.84 |
| RTN3 | 0.87 | 0.87 |
| AFG3L2 | 0.87 | 0.82 |
| CDS2 | 0.86 | 0.83 |
| MFN2 | 0.86 | 0.83 |
| CYFIP2 | 0.86 | 0.87 |
| TRIM37 | 0.86 | 0.83 |
| NARS | 0.86 | 0.80 |
| NDUFS1 | 0.86 | 0.84 |
| PRKAR1A | 0.86 | 0.84 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.67 | -0.48 |
| AF347015.18 | -0.58 | -0.42 |
| HIGD1B | -0.58 | -0.44 |
| MT-CO2 | -0.57 | -0.42 |
| AP002478.3 | -0.57 | -0.47 |
| AF347015.8 | -0.57 | -0.41 |
| AF347015.31 | -0.56 | -0.43 |
| AF347015.2 | -0.56 | -0.38 |
| C1orf54 | -0.56 | -0.52 |
| AL139819.3 | -0.56 | -0.48 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003677 | DNA binding | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0006334 | nucleosome assembly | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0000786 | nucleosome | IEA | - | |
| GO:0005634 | nucleus | IEA | - | |
| GO:0005694 | chromosome | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG SYSTEMIC LUPUS ERYTHEMATOSUS | 140 | 100 | All SZGR 2.0 genes in this pathway |
| DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA UP | 368 | 234 | All SZGR 2.0 genes in this pathway |
| GAL LEUKEMIC STEM CELL DN | 244 | 153 | All SZGR 2.0 genes in this pathway |