Gene Page

Gene Page: PARD6B

Summary

GeneID

84612

Symbol

PARD6B

Synonyms

PAR6B

Description

par-6 partitioning defective 6 homolog beta (C. elegans)

Locus tag

Gene type

protein-coding

Map location

20q13.13

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

14676191

GO:0005515

protein binding

TAS

14676191

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007409

axonogenesis

TAS

neuron, axon, neurite (GO term level: 12)

14676191

GO:0007163

establishment or maintenance of cell polarity

TAS

14676191

GO:0007049

cell cycle

IEA

GO:0007043

cell-cell junction assembly

TAS

12545177

GO:0051301

cell division

IEA

GO:0030334

regulation of cell migration

TAS

14676191

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005923

tight junction

IDA

Brain (GO term level: 10)

12545177

GO:0005737

cytoplasm

IEA

GO:0005886

plasma membrane

IDA

12545177

GO:0030054

cell junction

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CDC42	CDC42Hs \| G25K	cell division cycle 42 (GTP binding protein, 25kDa)	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	10934474 \|11162552
PARD3	ASIP \| Baz \| Bazooka \| FLJ21015 \| PAR3 \| PAR3alpha \| PARD3A \| SE2-5L16 \| SE2-5LT1 \| SE2-5T2	par-3 partitioning defective 3 homolog (C. elegans)	Affinity Capture-Western	BioGRID	12459187
RHOQ	ARHQ \| RASL7A \| TC10 \| TC10A	ras homolog gene family, member Q	Reconstituted Complex Two-hybrid	BioGRID	10934474 \|11162552

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	2577	2583	m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-128	2967	2973	1A	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	2967	2973	1A	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-17-5p/20/93.mr/106/519.d	1830	1836	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-200bc/429	3128	3134	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-205	2227	2233	1A	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-27	2967	2974	1A,m8	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	2967	2974	1A,m8	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-320	3200	3206	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-369-3p	3147	3153	1A	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-374	3147	3154	1A,m8	hsa-miR-374	UUAUAAUACAACCUGAUAAGUG
miR-381	3239	3246	1A,m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-493-5p	2653	2659	1A	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-505	2390	2396	1A	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.