Gene Page: SIP1

Summary
GeneID  8487
Symbol  SIP1
Synonyms  GEMIN2|SIP1-delta
Description  survival of motor neuron protein interacting protein 1
See related  HGNC:10884|MIM:602595|Ensembl:ENSG00000092208|HPRD:03999|
Locus tag  -
Gene type  protein-coding
Map location  14q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 2.017 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ETS20.900.82
CBX70.890.82
ZFYVE280.890.80
ZBTB7A0.880.76
PHF150.880.80
CNTNAP10.880.84
LGI30.880.79
MAP1A0.880.79
SIRPA0.880.85
EHD30.870.78
Top 10 negatively co-expressed genes
BCL7C-0.60-0.72
C9orf46-0.58-0.67
GTF3C6-0.55-0.60
RPL12-0.54-0.66
RPL35-0.54-0.68
DYNLT1-0.54-0.72
RPS19P3-0.53-0.74
RPL36-0.53-0.69
RPL23A-0.53-0.65
PPP1R14B-0.53-0.68
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI11714716 
GO:0031202RNA splicing factor activity, transesterification mechanismTAS9323129 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000245spliceosome assemblyTAS9323129 
GO:0000387spliceosomal snRNP biogenesisEXP15130578 
GO:0008380RNA splicingTAS9323129 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10531003 
GO:0005634nucleusTAS9323130 
GO:0005654nucleoplasmEXP10531003 
GO:0005681spliceosomeTAS9323129 
GO:0005737cytoplasmTAS9323130 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CTBP1BARS | MGC104684C-terminal binding protein 1Affinity Capture-WesternBioGRID12714599 
DDX20DKFZp434H052 | DP103 | GEMIN3DEAD (Asp-Glu-Ala-Asp) box polypeptide 20Affinity Capture-Western
Reconstituted Complex		BioGRID10601333 |11914277 
DHX9DDX9 | LKP | NDHII | RHADEAH (Asp-Glu-Ala-His) box polypeptide 9-HPRD,BioGRID11149922 
FBLFIB | FLRN | RNU3IP1fibrillarinAffinity Capture-WesternBioGRID11509230 
GAR1NOLA1GAR1 ribonucleoprotein homolog (yeast)Affinity Capture-WesternBioGRID11509230 
GEMIN5DKFZp586M1824 | MGC142174gem (nuclear organelle) associated protein 5-HPRD,BioGRID11714716 
GEMIN6FLJ23459gem (nuclear organelle) associated protein 6Affinity Capture-WesternBioGRID11748230 
LGALS1DKFZp686E23103 | GAL1 | GBPlectin, galactoside-binding, soluble, 1Affinity Capture-WesternBioGRID11522829 
RNPS1E5.1 | MGC117332RNA binding protein S1, serine-rich domainAffinity Capture-MSBioGRID17353931 
SFRS1ASF | MGC5228 | SF2 | SF2p33 | SRp30asplicing factor, arginine/serine-rich 1-HPRD9447963 
SFRS2PR264 | SC-35 | SC35 | SFRS2A | SRp30bsplicing factor, arginine/serine-rich 2-HPRD9447963 
SFRS3SRp20splicing factor, arginine/serine-rich 3-HPRD9447963 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomeric-HPRD,BioGRID9323129 
SMN2BCD541 | C-BCD541 | FLJ76644 | MGC20996 | MGC5208 | SMNCsurvival of motor neuron 2, centromeric-HPRD9323129 |10942426 
SNRNP70RNPU1Z | RPU1 | SNRP70 | U170K | U1AP | U1RNPsmall nuclear ribonucleoprotein 70kDa (U1)-HPRD9447963 
STXBP3MUNC18-3 | MUNC18C | PSP | UNC-18Csyntaxin binding protein 3-HPRD12065586 
U2AF2U2AF65U2 small nuclear RNA auxiliary factor 2-HPRD9447963 
 


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