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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CNTNAP1

Summary

GeneID

8506

Symbol

CNTNAP1

Synonyms

CASPR|CNTNAP|NRXN4|P190

Description

contactin associated protein 1

Locus tag

Gene type

protein-coding

Map location

17q21

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

EFEMP2

0.65

0.70

COMMD4

0.65

0.63

NAGLU

0.63

0.64

PEMT

0.63

0.51

NT5C

0.62

0.60

DOK1

0.62

DNAJC4

0.61

0.63

GSTP1

0.60

0.52

CPNE2

0.60

0.41

VEGFB

0.60

0.65

Top 10 negatively co-expressed genes

CDC40

-0.37

-0.45

DNAJB14

-0.37

-0.42

PRKACB

-0.37

-0.44

MAP9

-0.37

-0.41

CCDC91

-0.36

-0.41

IL1RAPL1

-0.36

-0.41

OSBPL3

-0.36

-0.37

HOMER1

-0.36

-0.38

CACNB4

-0.36

-0.37

FBXW7

-0.35

-0.36

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005102

receptor binding

IEA

Neurotransmitter (GO term level: 4)

GO:0004872

receptor activity

TAS

9118959

GO:0005070

SH3/SH2 adaptor activity

TAS

9118959

GO:0017124

SH3 domain binding

IEA

GO:0016493

C-C chemokine receptor activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007204

elevation of cytosolic calcium ion concentration

IEA

GO:0007155

cell adhesion

IEA

GO:0007165

signal transduction

TAS

9118959

GO:0006935

chemotaxis

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016020

membrane

IEA

GO:0005887

integral to plasma membrane

TAS

9118959

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
KCNA1	AEMK \| EA1 \| HBK1 \| HUK1 \| KV1.1 \| MBK1 \| MGC126782 \| MGC138385 \| MK1 \| RBK1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	Affinity Capture-Western	BioGRID	14592966
KCNA2	HBK5 \| HK4 \| HUKIV \| KV1.2 \| MGC50217 \| MK2 \| NGK1 \| RBK2	potassium voltage-gated channel, shaker-related subfamily, member 2	Affinity Capture-Western	BioGRID	14592966
NFASC	DKFZp686P2250 \| FLJ46866 \| KIAA0756 \| NF \| NRCAML	neurofascin homolog (chicken)	-	HPRD	11839274
PTPRB	DKFZp686E2262 \| DKFZp686H15164 \| FLJ44133 \| HPTP-BETA \| HPTPB \| MGC142023 \| MGC59935 \| PTPB \| R-PTP-BETA \| VEPTP	protein tyrosine phosphatase, receptor type, B	-	HPRD	9118959
RHOA	ARH12 \| ARHA \| RHO12 \| RHOH12	ras homolog gene family, member A	-	HPRD	9407060
RTN4	ASY \| NI220/250 \| NOGO \| NOGO-A \| NOGOC \| NSP \| NSP-CL \| Nbla00271 \| Nbla10545 \| Nogo-B \| Nogo-C \| RTN-X \| RTN4-A \| RTN4-B1 \| RTN4-B2 \| RTN4-C	reticulon 4	-	HPRD,BioGRID	14592966

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	770	776	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	770	776	m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-133	16	23	1A,m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	16	23	1A,m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-135	609	616	1A,m8	hsa-miR-135a	UAUGGCUUUUUAUUCCUAUGUGA
miR-135	609	616	1A,m8	hsa-miR-135b	UAUGGCUUUUCAUUCCUAUGUG
miR-15/16/195/424/497	425	431	1A	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-186	798	805	1A,m8	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-299-5p	195	201	1A	hsa-miR-299-5p	UGGUUUACCGUCCCACAUACAU
miR-34/449	188	194	m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-34b	189	196	1A,m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-370	371	377	m8	hsa-miR-370^brain	GCCUGCUGGGGUGGAACCUGG
miR-410	877	883	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-503	425	431	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-7	467	473	1A	hsa-miR-7^SZ	UGGAAGACUAGUGAUUUUGUUG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.