Gene Page: EIF3F

Summary
GeneID  8665
Symbol  EIF3F
Synonyms  EIF3S5|eIF3-p47
Description  eukaryotic translation initiation factor 3, subunit F
See related  HGNC:3275|MIM:603914|Ensembl:ENSG00000175390|HPRD:04887|
Locus tag  -
Gene type  protein-coding
Map location  11p15.4
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 1.2569 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
KANK10.810.82
ITPKB0.800.84
PMP20.800.83
SASH10.790.82
DOCK10.780.78
SOX130.780.80
ATP13A40.780.81
ITPR20.770.76
SSPN0.770.79
CGNL10.770.78
Top 10 negatively co-expressed genes
NR2C2AP-0.53-0.65
COMMD3-0.51-0.64
ING4-0.50-0.58
ARL4D-0.49-0.50
AC011491.1-0.49-0.58
PLEKHO1-0.49-0.58
ISLR2-0.48-0.51
MED19-0.48-0.58
ALKBH2-0.48-0.61
IGFBP2-0.47-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003743translation initiation factor activityTAS9341143 
GO:0005515protein bindingIPI17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006446regulation of translational initiationTAS9341143 
GO:0006412translationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP12588972 
GO:0005852eukaryotic translation initiation factor 3 complexTAS9341143 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CDC2L2CDC2L3 | CDK11-p110 | CDK11-p46 | CDK11-p58 | MGC131975 | PITSLRE | p58GTAcell division cycle 2-like 2 (PITSLRE proteins)Affinity Capture-Western
Two-hybrid		BioGRID12446680 
DKC1CBF5 | DKC | FLJ97620 | NAP57 | NOLA4 | XAP101 | dyskerindyskeratosis congenita 1, dyskerinTwo-hybridBioGRID16169070 
EEF1A1CCS-3 | CCS3 | EEF-1 | EEF1A | EF-Tu | EF1A | FLJ25721 | GRAF-1EF | HNGC:16303 | LENG7 | MGC102687 | MGC131894 | MGC16224 | PTI1 | eEF1A-1eukaryotic translation elongation factor 1 alpha 1Two-hybridBioGRID16169070 
EIF1BGC20eukaryotic translation initiation factor 1BAffinity Capture-MSBioGRID17353931 
EIF3AEIF3 | EIF3S10 | KIAA0139 | P167 | TIF32 | eIF3-p170 | eIF3-theta | p180 | p185eukaryotic translation initiation factor 3, subunit AAffinity Capture-MS
Co-purification		BioGRID14519125 |17353931 
EIF3MB5 | FLJ29030 | GA17 | PCID1 | hfl-B5eukaryotic translation initiation factor 3, subunit MTwo-hybridBioGRID16169070 
FRAP1FLJ44809 | FRAP | FRAP2 | MTOR | RAFT1 | RAPT1FK506 binding protein 12-rapamycin associated protein 1Affinity Capture-Western
Two-hybrid		BioGRID16541103 
HAX1FLJ17042 | FLJ18492 | FLJ93803 | HCLSBP1 | HS1BP1 | SCN3HCLS1 associated protein X-1Two-hybridBioGRID16189514 
PTNHARP | HBGF8 | HBNF | NEGF1pleiotrophinTwo-hybridBioGRID16169070 
RPS6KB1PS6K | S6K | S6K1 | STK14A | p70(S6K)-alpha | p70-S6K | p70-alpharibosomal protein S6 kinase, 70kDa, polypeptide 1Affinity Capture-MSBioGRID16286006 
 


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