Gene Page: CDC23

Summary
GeneID  8697
Symbol  CDC23
Synonyms  APC8
Description  cell division cycle 23 homolog (S. cerevisiae)
See related  HGNC:1724|MIM:603462|Ensembl:ENSG00000094880|HPRD:07221|
Locus tag  -
Gene type  protein-coding
Map location  5q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CLP10.920.89
RPUSD20.920.89
CNO0.910.90
TMEM1990.890.88
GRWD10.890.92
BYSL0.890.89
EEFSEC0.890.90
ZC3HC10.880.83
ZBTB220.880.88
RIC8A0.880.87
Top 10 negatively co-expressed genes
AF347015.33-0.72-0.82
MT-CO2-0.72-0.82
AF347015.31-0.72-0.81
AF347015.27-0.71-0.81
AF347015.8-0.70-0.82
MT-CYB-0.70-0.81
AF347015.15-0.68-0.81
FXYD1-0.67-0.78
AF347015.9-0.66-0.81
C5orf53-0.66-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005488bindingIEA-
GO:0004842ubiquitin-protein ligase activityTAS12629511 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000080G1 phase of mitotic cell cycleIDA12629511 
GO:0006511ubiquitin-dependent protein catabolic processTAS9790767 
GO:0007049cell cycleTAS12188893 
GO:0007080mitotic metaphase plate congressionIDA14657031 
GO:0007096regulation of exit from mitosisTAS9790767 
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processEXP11285280 
GO:0051301cell divisionIEA-
GO:0030071regulation of mitotic metaphase/anaphase transitionIDA9790767 
GO:0030071regulation of mitotic metaphase/anaphase transitionIEA-
GO:0051436negative regulation of ubiquitin-protein ligase activity during mitotic cell cycleEXP14593737 |15029244 
GO:0051437positive regulation of ubiquitin-protein ligase activity during mitotic cell cycleEXP10793135 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10793135 |11285280 |11535616 
|11742988 |12070128 
GO:0005622intracellularIDA11256614 
GO:0005654nucleoplasmEXP10548110 |11340163 |15029244 
GO:0005680anaphase-promoting complexIDA14657031 
GO:0005680anaphase-promoting complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANAPC1APC1 | MCPR | TSG24anaphase promoting complex subunit 1Co-purificationBioGRID11076961 
ANAPC4APC4anaphase promoting complex subunit 4Affinity Capture-WesternBioGRID12956947 
ANAPC5APC5anaphase promoting complex subunit 5-HPRD,BioGRID10922056 
APC2APCLadenomatosis polyposis coli 2Affinity Capture-WesternBioGRID12956947 
CDC27APC3 | CDC27Hs | D0S1430E | D17S978E | HNUCcell division cycle 27 homolog (S. cerevisiae)Affinity Capture-WesternBioGRID12956947 
CDH1Arc-1 | CD324 | CDHE | ECAD | LCAM | UVOcadherin 1, type 1, E-cadherin (epithelial)Reconstituted ComplexBioGRID12956947 
RAD54BFSBP | RDH54RAD54 homolog B (S. cerevisiae)Two-hybridBioGRID16189514 
RBPMSHERMESRNA binding protein with multiple splicingTwo-hybridBioGRID16189514 
TSC22D4THG-1 | THG1TSC22 domain family, member 4Two-hybridBioGRID16189514 
 


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