|
|
| GeneID |
8745
|
| Symbol |
ADAM23
|
| Synonyms |
MDC3
|
| Description |
ADAM metallopeptidase domain 23 |
| See related |
HGNC:202|MIM:603710|Ensembl:ENSG00000114948|HPRD:04752| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
2q33 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00916 | | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01016 | | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0357 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| EXD3 | 0.88 | 0.70 | | |
| GSDMB | 0.86 | 0.77 | | |
| PLA2G4B | 0.84 | 0.73 | | |
| CSAD | 0.84 | 0.73 | | |
| NEIL1 | 0.83 | 0.75 | | |
| GNB3 | 0.82 | 0.69 | | |
| TFAP2E | 0.81 | 0.74 | | |
| AC011511.1 | 0.81 | 0.73 | | |
| AC174470.2 | 0.81 | 0.63 | | |
| JMJD7-PLA2G4B | 0.80 | 0.65 | | |
Top 10 negatively co-expressed genes | | ITM2A | -0.37 | -0.33 | | |
| MYL12A | -0.36 | -0.35 | | |
| TM4SF18 | -0.35 | -0.31 | | |
| ELTD1 | -0.34 | -0.23 | | |
| NET1 | -0.34 | -0.27 | | |
| TM4SF1 | -0.34 | -0.27 | | |
| GIMAP5 | -0.32 | -0.24 | | |
| HLA-C | -0.32 | -0.18 | | |
| FCGRT | -0.31 | -0.16 | | |
| AF347015.31 | -0.31 | -0.18 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005178 | integrin binding | TAS | | 9693107 |
| GO:0005515 | protein binding | IEA | | - |
| GO:0004222 | metalloendopeptidase activity | IEA | | - |
| GO:0008270 | zinc ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007417 | central nervous system development | TAS | Brain (GO term level: 6) | 9693107 |
| GO:0007155 | cell adhesion | IEA | | - |
| GO:0006508 | proteolysis | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005576 | extracellular region | IEA | | - |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 9693107 |
| |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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