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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: LIN7A

Summary

GeneID

8825

Symbol

LIN7A

Synonyms

LIN-7A|LIN7|MALS-1|MGC148143|TIP-33|VELI1

Description

lin-7 homolog A (C. elegans)

Locus tag

Gene type

protein-coding

Map location

12q21

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 3

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

NUP85

0.88

AP4M1

0.87

0.90

HDAC3

0.87

0.86

ACD

0.87

0.88

MOSPD3

0.86

0.84

PRR14

0.86

0.85

MUS81

0.86

0.88

AAAS

0.86

0.83

MAD2L2

0.85

0.86

CCDC130

0.85

0.86

Top 10 negatively co-expressed genes

AF347015.27

-0.72

-0.84

AF347015.31

-0.72

-0.83

MT-CYB

-0.70

-0.84

MT-CO2

-0.70

-0.82

AF347015.8

-0.69

-0.84

AF347015.33

-0.69

-0.82

AF347015.15

-0.68

-0.83

AF347015.2

-0.67

-0.85

AF347015.26

-0.64

-0.82

HLA-F

-0.63

-0.65

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

11311936

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006461

protein complex assembly

TAS

9482110

GO:0006887

exocytosis

TAS

9753324

GO:0015031

protein transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005923

tight junction

IEA

Brain (GO term level: 10)

GO:0019717

synaptosome

IEA

Synap, Brain (GO term level: 7)

GO:0045211

postsynaptic membrane

IEA

Synap, Neurotransmitter (GO term level: 5)

GO:0045202

synapse

IEA

neuron, Synap, Neurotransmitter, Glial (GO term level: 2)

GO:0005886

plasma membrane

IEA

GO:0016323

basolateral plasma membrane

IEA

GO:0030054

cell junction

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
APBA1	D9S411E \| MINT1 \| X11 \| X11A \| X11ALPHA	amyloid beta (A4) precursor protein-binding, family A, member 1	Affinity Capture-Western	BioGRID	9822620
BAIAP2	BAP2 \| IRSP53	BAI1-associated protein 2	-	HPRD	14596909
CASK	CAGH39 \| CMG \| FLJ22219 \| FLJ31914 \| LIN2 \| MICPCH \| TNRC8	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	Affinity Capture-Western in vitro in vivo Reconstituted Complex	BioGRID	9753324 \|9822620 \|14960569
CASK	CAGH39 \| CMG \| FLJ22219 \| FLJ31914 \| LIN2 \| MICPCH \| TNRC8		-	HPRD	9753324\|9822620 \|9952408
DLG1	DKFZp761P0818 \| DKFZp781B0426 \| DLGH1 \| SAP97 \| dJ1061C18.1.1 \| hdlg	discs, large homolog 1 (Drosophila)	Affinity Capture-Western	BioGRID	14960569
DLG2	DKFZp781D1854 \| DKFZp781E0954 \| FLJ37266 \| MGC131811 \| PSD-93	discs, large homolog 2, chapsyn-110 (Drosophila)	-	HPRD,BioGRID	9753324
DLG3	KIAA1232 \| MRX \| MRX90 \| NE-Dlg \| NEDLG \| SAP102	discs, large homolog 3 (neuroendocrine-dlg, Drosophila)	-	HPRD,BioGRID	9753324
DLG4	FLJ97752 \| FLJ98574 \| PSD95 \| SAP90	discs, large homolog 4 (Drosophila)	-	HPRD,BioGRID	10341223
GRIN2B	MGC142178 \| MGC142180 \| NMDAR2B \| NR2B \| hNR3	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	in vitro	BioGRID	10341223
KCNJ12	FLJ14167 \| IRK2 \| KCNJN1 \| Kir2.2 \| Kir2.2v \| hIRK \| hIRK1 \| hkir2.2x \| kcnj12x	potassium inwardly-rectifying channel, subfamily J, member 12	-	HPRD,BioGRID	14960569 \|15024025
KCNJ4	HIR \| HIRK2 \| HRK1 \| IRK3 \| Kir2.3 \| MGC142066 \| MGC142068	potassium inwardly-rectifying channel, subfamily J, member 4	Affinity Capture-Western	BioGRID	14960569
MPP5	FLJ12615 \| PALS1	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	-	HPRD	10753959
MPP6	PALS2 \| VAM-1 \| VAM1 \| p55T	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)	-	HPRD,BioGRID	10753959 \|11311936

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-134	38	44	1A	hsa-miR-134^brain	UGUGACUGGUUGACCAGAGGG
miR-27	116	122	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	116	122	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-30-3p	277	283	m8	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	277	283	m8	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.