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| GeneID |
8890
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| Symbol |
EIF2B4
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| Synonyms |
DKFZp586J0119|EIF-2B|EIF2B|EIF2Bdelta
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| Description |
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa |
| See related |
HGNC:3260|MIM:606687|Ensembl:ENSG00000115211|HPRD:09459| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
2p23.3 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| AGTPBP1 | 0.90 | 0.93 | | |
| MDGA2 | 0.89 | 0.91 | | |
| CLASP2 | 0.89 | 0.93 | | |
| WDR44 | 0.89 | 0.92 | | |
| RAB9B | 0.88 | 0.91 | | |
| PAPD5 | 0.88 | 0.92 | | |
| PCYOX1 | 0.88 | 0.91 | | |
| RTN4 | 0.87 | 0.92 | | |
| GNPTAB | 0.87 | 0.91 | | |
| MGEA5 | 0.87 | 0.91 | | |
Top 10 negatively co-expressed genes | | AF347015.31 | -0.70 | -0.80 | | |
| MT-CO2 | -0.69 | -0.81 | | |
| FXYD1 | -0.69 | -0.79 | | |
| TSC22D4 | -0.67 | -0.75 | | |
| SLC25A18 | -0.67 | -0.76 | | |
| ROM1 | -0.67 | -0.77 | | |
| AF347015.33 | -0.67 | -0.76 | | |
| MT-CYB | -0.67 | -0.77 | | |
| HIGD1B | -0.66 | -0.79 | | |
| HSD17B14 | -0.66 | -0.75 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | IDA | | 11323413 |
| GO:0005085 | guanyl-nucleotide exchange factor activity | IMP | | 15054402 |
| GO:0003743 | translation initiation factor activity | IDA | | 16289705 |
| GO:0003743 | translation initiation factor activity | IEA | | - |
| GO:0005515 | protein binding | IPI | | 15060152 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0014003 | oligodendrocyte development | IMP | axon, oligodendrocyte, Glial (GO term level: 10) | 15217090 |
| GO:0042552 | myelination | IMP | neuron, axon, Brain, oligodendrocyte (GO term level: 13) | 14566705 |
| GO:0001541 | ovarian follicle development | IMP | | 15507143 |
| GO:0006413 | translational initiation | IDA | | 16289705 |
| GO:0006417 | regulation of translation | NAS | | 12556349 |
| GO:0009408 | response to heat | ISS | | - |
| GO:0009408 | response to heat | TAS | | 12499492 |
| GO:0009749 | response to glucose stimulus | ISS | | - |
| GO:0043434 | response to peptide hormone stimulus | ISS | | - |
| GO:0044237 | cellular metabolic process | IEA | | - |
| GO:0051716 | cellular response to stimulus | IDA | | 8626696 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005851 | eukaryotic translation initiation factor 2B complex | IDA | | 11323413 |15060152 |
| GO:0005737 | cytoplasm | IDA | | 11323413 |
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