Gene Page: CDKL2

Summary
GeneID  8999
Symbol  CDKL2
Synonyms  KKIAMRE|P56
Description  cyclin-dependent kinase-like 2 (CDC2-related kinase)
See related  HGNC:1782|MIM:603442|Ensembl:ENSG00000138769|HPRD:16021|
Locus tag  -
Gene type  protein-coding
Map location  4q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SAMD9L0.600.60
ANXA50.590.57
CFI0.580.59
PLBD10.580.57
SGCE0.560.51
AP003117.10.550.59
RP11-244H3.10.550.57
FZD60.550.55
SP1000.550.58
ECM20.540.61
Top 10 negatively co-expressed genes
BOP1-0.46-0.45
XKR7-0.46-0.43
DPF1-0.46-0.44
SH2B2-0.45-0.46
NOVA2-0.45-0.44
NEUROD2-0.45-0.35
SOX12-0.45-0.43
ZNF860-0.45-0.38
DGKD-0.44-0.39
SBK1-0.44-0.40
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004693cyclin-dependent protein kinase activityIEAneuron (GO term level: 8)-
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationIEA-
GO:0007165signal transductionTAS9000130 
GO:0007548sex differentiationTAS9000130 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CBLC-CBL | CBL2 | RNF55Cas-Br-M (murine) ecotropic retroviral transforming sequence-HPRD7721825 
IRF3-interferon regulatory factor 3IRF-3 interacts with the P56 promoter.BIND15502848 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-181295301m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-30-3p248324901A,m8hsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
miR-409-3p135513611Ahsa-miR-409-3pCGAAUGUUGCUCGGUGAACCCCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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