Gene Page

Gene Page: UNC5A

Summary

GeneID

90249

Symbol

UNC5A

Synonyms

FLJ16449|KIAA1976|UNC5H1

Description

unc-5 homolog A (C. elegans)

Locus tag

Gene type

protein-coding

Map location

5q35.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.0276

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

GO:0005515

protein binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007165

signal transduction

IEA

GO:0006915

apoptosis

IEA

GO:0007275

multicellular organismal development

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016021

integral to membrane

IEA

GO:0005886

plasma membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DAPK1	DAPK \| DKFZp781I035	death-associated protein kinase 1	UNC5A (UNC5H1) interacts with DAPK1 (DAPK). This interaction was modelled on a demonstrated interaction between rat UNC5H1 and human DAPK.	BIND	15729359
MAGED1	DLXIN-1 \| NRAGE	melanoma antigen family D, 1	-	HPRD,BioGRID	12598531
NTN1	NTN1L	netrin 1	Reconstituted Complex	BioGRID	12810718

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	296	302	m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-103/107	675	681	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	675	681	m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-138	29	35	m8	hsa-miR-138^brain	AGCUGGUGUUGUGAAUC
miR-143	607	613	1A	hsa-miR-143^brain	UGAGAUGAAGCACUGUAGCUCA
miR-143	607	613	1A	hsa-miR-143^brain	UGAGAUGAAGCACUGUAGCUCA
miR-153	401	407	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-153	401	407	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-181	979	986	1A,m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-203.1	408	414	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-208	893	899	1A	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-28	379	385	m8	hsa-miR-28^brain	AAGGAGCUCACAGUCUAUUGAG
miR-320	32	38	m8	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-329	276	282	1A	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU
miR-410	993	999	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-448	401	407	1A	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-448	401	407	1A	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-452	403	410	1A,m8	hsa-miR-452	UGUUUGCAGAGGAAACUGAGAC
miR-491	79	86	1A,m8	hsa-miR-491^brain	AGUGGGGAACCCUUCCAUGAGGA
miR-493-5p	928	934	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-496	982	988	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-499	893	899	1A	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA
miR-93.hd/291-3p/294/295/302/372/373/520	910	916	1A	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.