Gene Page: RNF8

Summary
GeneID  9025
Symbol  RNF8
Synonyms  FLJ12013|KIAA0646
Description  ring finger protein 8
See related  HGNC:10071|MIM:611685|Ensembl:ENSG00000112130|HPRD:11521|
Locus tag  -
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SH3BP10.910.91
PDXP0.910.91
NRSN20.900.92
PPP1R3F0.890.90
ANKRD34A0.890.90
BEGAIN0.890.92
NACC10.880.85
CACNB10.880.85
CCKBR0.870.87
CHRM10.870.87
Top 10 negatively co-expressed genes
NSBP1-0.51-0.52
RAB13-0.48-0.53
EIF5B-0.46-0.51
AL139819.3-0.45-0.41
AF347015.18-0.45-0.27
ANP32B-0.44-0.50
AF347015.21-0.42-0.24
GNG11-0.42-0.38
AC010300.1-0.41-0.38
MYL12A-0.41-0.43
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15231747 |18001824 |18001825 
GO:0016874ligase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006511ubiquitin-dependent protein catabolic processIEA-
GO:0007049cell cycleIEA-
GO:0007067mitosisIEA-
GO:0006974response to DNA damage stimulusIEA-
GO:0051301cell divisionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
KIAA1712PS1TP3KIAA1712Two-hybridBioGRID16189514 
RNF8FLJ12013 | KIAA0646ring finger protein 8Biochemical ActivityBioGRID11322894 
RXRAFLJ00280 | FLJ00318 | FLJ16020 | FLJ16733 | MGC102720 | NR2B1retinoid X receptor, alpha-HPRD,BioGRID14981089 
UBE2E1UBCH6ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)-HPRD,BioGRID11322894 
UBE2E2FLJ25157 | UBCH8ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)-HPRD,BioGRID11322894 
UBE2E3UBCH9 | UbcM2ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)-HPRD,BioGRID11322894 
 


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