Gene Page: PSTPIP1

Summary
GeneID  9051
Symbol  PSTPIP1
Synonyms  CD2BP1|CD2BP1L|CD2BP1S|H-PIP|PAPAS|PSTPIP
Description  proline-serine-threonine phosphatase interacting protein 1
See related  HGNC:9580|MIM:606347|Ensembl:ENSG00000140368|HPRD:05891|
Locus tag  -
Gene type  protein-coding
Map location  15q24-q25.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ARHGEF70.920.93
UBN10.910.92
LARP4B0.910.92
MGAT50.900.92
KPNA60.900.91
ADAR0.890.91
ATRN0.890.90
SMCR80.890.90
KIAA14090.890.91
CEP680.880.91
Top 10 negatively co-expressed genes
AF347015.31-0.69-0.73
FXYD1-0.69-0.73
MT-CO2-0.68-0.73
AF347015.21-0.68-0.76
HIGD1B-0.68-0.74
HSD17B14-0.66-0.69
AF347015.8-0.66-0.71
CST3-0.66-0.72
MT-CYB-0.65-0.68
AF347015.33-0.65-0.67
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003824catalytic activityIEA-
GO:0003779actin bindingIEA-
GO:0005515protein bindingIPI17353931 
GO:0019903protein phosphatase bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionTAS9857189 
GO:0007165signal transductionTAS9857189 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042995cell projectionIEAaxon (GO term level: 4)-
GO:0001725stress fiberIEA-
GO:0005826contractile ringIEA-
GO:0005856cytoskeletonIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ABL1ABL | JTK7 | bcr/abl | c-ABL | p150 | v-ablc-abl oncogene 1, receptor tyrosine kinase-HPRD,BioGRID11163214 
ATICAICAR | AICARFT | FLJ93545 | IMPCHASE | PURH5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolaseAffinity Capture-MSBioGRID17353931 
BZW1BZAP45 | KIAA0005 | Nbla10236basic leucine zipper and W2 domains 1Affinity Capture-MSBioGRID17353931 
BZW2HSPC028 | MST017 | MSTP017basic leucine zipper and W2 domains 2Affinity Capture-MSBioGRID17353931 
CD2SRBC | T11CD2 molecule-HPRD,BioGRID9857189 
DDX21DKFZp686F21172 | GUA | GURDB | RH-II/GU | RH-II/GuADEAD (Asp-Glu-Ala-Asp) box polypeptide 21Affinity Capture-MSBioGRID17353931 
FDFT1DGPT | ERG9 | SQS | SSfarnesyl-diphosphate farnesyltransferase 1Affinity Capture-MSBioGRID17353931 
PTPN12PTP-PEST | PTPG1protein tyrosine phosphatase, non-receptor type 12-HPRD,BioGRID9422760 |11971877 
PTPN18BDP1 | PTP-HSCFprotein tyrosine phosphatase, non-receptor type 18 (brain-derived)Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID9265651 
RPL18A-ribosomal protein L18aAffinity Capture-MSBioGRID17353931 
RPL21DKFZp686C06101 | FLJ27458 | L21 | MGC104274 | MGC104275 | MGC71252ribosomal protein L21Affinity Capture-MSBioGRID17353931 
RPL23AFLJ27455 | MDA20ribosomal protein L23aAffinity Capture-MSBioGRID17353931 
RPL26-ribosomal protein L26Affinity Capture-MSBioGRID17353931 
RPL29HIP | HUMRPL29 | MGC88589ribosomal protein L29Affinity Capture-MSBioGRID17353931 
RPL3MGC104284 | TARBP-Bribosomal protein L3Affinity Capture-MSBioGRID17353931 
RPL31MGC88191ribosomal protein L31Affinity Capture-MSBioGRID17353931 
RPL32PP9932ribosomal protein L32Affinity Capture-MSBioGRID17353931 
RPL34MGC111005ribosomal protein L34Affinity Capture-MSBioGRID17353931 
RPL35-ribosomal protein L35Affinity Capture-MSBioGRID17353931 
RPL35A-ribosomal protein L35aAffinity Capture-MSBioGRID17353931 
RPL36DKFZp566B023ribosomal protein L36Affinity Capture-MSBioGRID17353931 
RPL36AL44L | MGC72020 | MIG6 | RPL44ribosomal protein L36aAffinity Capture-MSBioGRID17353931 
RPL37AMGC74786ribosomal protein L37aAffinity Capture-MSBioGRID17353931 
RUVBL1ECP54 | INO80H | NMP238 | PONTIN | Pontin52 | RVB1 | TIH1 | TIP49 | TIP49ARuvB-like 1 (E. coli)Affinity Capture-MSBioGRID17353931 
WASIMD2 | THC | WASPWiskott-Aldrich syndrome (eczema-thrombocytopenia)-HPRD,BioGRID9488710 
PSTPIP1 interacts with WASP.BIND11313252 
WASF1FLJ31482 | KIAA0269 | SCAR1 | WAVE | WAVE1WAS protein family, member 1-HPRD9804817 
WASF2SCAR2 | WAVE2 | dJ393P12.2WAS protein family, member 2-HPRD9804817 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY 6247All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_THE_NLRP3_INFLAMMASOME 129All SZGR genes in this pathway
REACTOME_INFLAMMASOMES 1712All SZGR genes in this pathway
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 4633All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_DN 11878All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP 5232All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 16280All SZGR genes in this pathway
MIKKELSEN_IPS_LCP_WITH_H3K4ME3 174100All SZGR genes in this pathway
MIKKELSEN_ES_LCP_WITH_H3K4ME3 14280All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway


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