Gene Page: LARGE

Summary
GeneID  9215
Symbol  LARGE
Synonyms  KIAA0609|MDC1D
Description  like-glycosyltransferase
See related  HGNC:6511|MIM:603590|Ensembl:ENSG00000133424|HPRD:04665|
Locus tag  CTA-282F2.1
Gene type  protein-coding
Map location  22q12.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008375acetylglucosaminyltransferase activityTAS9892679 
GO:0016757transferase activity, transferring glycosyl groupsTAS9892679 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006486protein amino acid glycosylationTAS9892679 
GO:0006044N-acetylglucosamine metabolic processTAS9892679 
GO:0006688glycosphingolipid biosynthetic processTAS9892679 
GO:0046716muscle maintenanceISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0030173integral to Golgi membraneTAS9892679 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DAG1156DAG | A3a | AGRNR | DAGdystroglycan 1 (dystrophin-associated glycoprotein 1)Alpha-DG interacts with LARGE. This interaction was modeled on a demonstrated interaction between rabbit alpha-DG and human LARGE.BIND15210115 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-132/21213361342m8hsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-199118311901A,m8hsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-30-5p123012371A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-495102108m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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