Gene Page: VAPA

Summary
GeneID  9218
Symbol  VAPA
Synonyms  MGC3745|VAP-33|VAP-A|VAP33|hVAP-33
Description  VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
See related  HGNC:12648|MIM:605703|Ensembl:ENSG00000101558|HPRD:09299|
Locus tag  -
Gene type  protein-coding
Map location  18p11.22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FBXO100.800.81
ZC3H12B0.800.80
CLSTN10.790.84
GARNL40.790.78
ARHGEF30.790.81
OXCT10.790.82
GRAMD1B0.780.80
TASP10.780.79
MYRIP0.770.78
RIMBP20.770.81
Top 10 negatively co-expressed genes
AF347015.21-0.41-0.35
C1orf54-0.38-0.40
AF347015.18-0.37-0.35
PLA2G5-0.37-0.30
S100A13-0.37-0.31
AF347015.2-0.37-0.32
AL139819.3-0.36-0.34
AF347015.31-0.36-0.35
ENHO-0.36-0.38
FXYD1-0.36-0.28
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIMP12761501 
GO:0005515protein bindingIPI16895911 
GO:0005198structural molecule activityIEA-
GO:0046982protein heterodimerization activityIPI9920726 |16227268 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006944membrane fusionTAS9657962 
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIMP12761501 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005923tight junctionIDABrain (GO term level: 10)10523508 
GO:0012505endomembrane systemIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIDA10523508 
GO:0048471perinuclear region of cytoplasmIDA16895911 
GO:0031982vesicleIDA10523508 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
OSBPOSBP1oxysterol binding proteinAffinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID12023275 
SNF1LKMSK | SIK | SIK1SNF1-like kinase-HPRD9920726 
VAMP1DKFZp686H12131 | SYB1 | VAMP-1vesicle-associated membrane protein 1 (synaptobrevin 1)-HPRD,BioGRID9657962 
VAMP2FLJ11460 | SYB2 | VAMP-2vesicle-associated membrane protein 2 (synaptobrevin 2)-HPRD,BioGRID9657962 
VAPAMGC3745 | VAP-33 | VAP-A | VAP33 | hVAP-33VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa-HPRD9920726 
VAPBALS8 | VAMP-B | VAMP-C | VAP-B | VAP-CVAMP (vesicle-associated membrane protein)-associated protein B and CReconstituted ComplexBioGRID9920726 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-132/2125915971Ahsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-194364370m8hsa-miR-194UGUAACAGCAACUCCAUGUGGA
miR-203.170761Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-2324152421m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-30-5p5965m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-323241524211Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-3353713771Ahsa-miR-335brainUCAAGAGCAAUAACGAAAAAUGU
miR-3784124181Ahsa-miR-378CUCCUGACUCCAGGUCCUGUGU
miR-3811982041Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-4215195251Ahsa-miR-421GGCCUCAUUAAAUGUUUGUUG
miR-4511511571Ahsa-miR-451brainAAACCGUUACCAUUACUGAGUUU
miR-5433263321Ahsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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