Gene Page

Gene Page: SFRS11

Summary

GeneID

9295

Symbol

SFRS11

Synonyms

DKFZp686M13204|dJ677H15.2|p54

Description

splicing factor, arginine/serine-rich 11

Locus tag

Gene type

protein-coding

Map location

1p31

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.02692

Expression

P value: 1.382

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0003676

nucleic acid binding

IEA

GO:0003723

RNA binding

IEA

GO:0005515

protein binding

IPI

17353931

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000398

nuclear mRNA splicing, via spliceosome

EXP

12226669

GO:0008380

RNA splicing

TAS

1896467

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IDA

18029348

GO:0005634

nucleus

TAS

1896467

GO:0005730

nucleolus

IDA

18029348

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
PUF60	FIR \| FLJ31379 \| RoBPI \| SIAHBP1	poly-U binding splicing factor 60KDa	Affinity Capture-MS	BioGRID	17353931
PUF60	FIR \| FLJ31379 \| RoBPI \| SIAHBP1	poly-U binding splicing factor 60KDa	-	HPRD	10606266
RNPS1	E5.1 \| MGC117332	RNA binding protein S1, serine-rich domain	RNPS1 interacts with p54.	BIND	14729963
SFRS1	ASF \| MGC5228 \| SF2 \| SF2p33 \| SRp30a	splicing factor, arginine/serine-rich 1	-	HPRD,BioGRID	8816452
SFRS2	PR264 \| SC-35 \| SC35 \| SFRS2A \| SRp30b	splicing factor, arginine/serine-rich 2	-	HPRD,BioGRID	8816452
SNRNP70	RNPU1Z \| RPU1 \| SNRP70 \| U170K \| U1AP \| U1RNP	small nuclear ribonucleoprotein 70kDa (U1)	-	HPRD	8816452
TOP1	TOPI	topoisomerase (DNA) I	-	HPRD,BioGRID	9756848
U2AF2	U2AF65	U2 small nuclear RNA auxiliary factor 2	-	HPRD,BioGRID	8816452

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-130/301	595	601	1A	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-143	79	86	1A,m8	hsa-miR-143^brain	UGAGAUGAAGCACUGUAGCUCA
miR-148/152	389	396	1A,m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-15/16/195/424/497	245	251	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-183	1130	1136	m8	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-217	1005	1011	1A	hsa-miR-217	UACUGCAUCAGGAACUGAUUGGAU
miR-370	284	290	m8	hsa-miR-370^brain	GCCUGCUGGGGUGGAACCUGG
miR-381	977	983	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-409-3p	491	497	m8	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU
miR-493-5p	1141	1147	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-495	471	477	m8	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.