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| GeneID |
9507
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| Symbol |
ADAMTS4
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| Synonyms |
ADAMTS-2|ADAMTS-4|ADMP-1|KIAA0688
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| Description |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
| See related |
HGNC:220|MIM:603876|Ensembl:ENSG00000158859|HPRD:04853| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
1q21-q23 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00814 | | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.2098 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| TAPBP | 0.80 | 0.75 | | |
| SHANK3 | 0.79 | 0.81 | | |
| GALNT9 | 0.79 | 0.73 | | |
| KNDC1 | 0.78 | 0.81 | | |
| PIGZ | 0.78 | 0.80 | | |
| GPR123 | 0.78 | 0.79 | | |
| LPCAT4 | 0.77 | 0.79 | | |
| TNK2 | 0.77 | 0.78 | | |
| LENG3 | 0.77 | 0.77 | | |
| SNAI3 | 0.77 | 0.78 | | |
Top 10 negatively co-expressed genes | | RPS20 | -0.48 | -0.59 | | |
| C9orf46 | -0.48 | -0.50 | | |
| TPT1 | -0.47 | -0.48 | | |
| RPL24 | -0.46 | -0.50 | | |
| RPS6 | -0.46 | -0.50 | | |
| SNRPG | -0.46 | -0.55 | | |
| RPL31 | -0.45 | -0.48 | | |
| RPS3AP47 | -0.45 | -0.44 | | |
| RPL27 | -0.44 | -0.47 | | |
| RPL35A | -0.44 | -0.54 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0002020 | protease binding | IPI | | 14744861 |
| GO:0004222 | metalloendopeptidase activity | IEA | | - |
| GO:0008270 | zinc ion binding | IEA | | - |
| GO:0008233 | peptidase activity | TAS | | 10751421 |
| GO:0046872 | metal ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001501 | skeletal system development | TAS | | 10356395 |
| GO:0006508 | proteolysis | IEA | | - |
| GO:0006508 | proteolysis | TAS | | 10751421 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005576 | extracellular region | IEA | | - |
| GO:0005578 | proteinaceous extracellular matrix | IEA | | - |
| GO:0005615 | extracellular space | IDA | | 14744861 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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