Gene Page: EIF5B

Summary
GeneID  9669
Symbol  EIF5B
Synonyms  DKFZp434I036|FLJ10524|IF2|KIAA0741
Description  eukaryotic translation initiation factor 5B
See related  HGNC:30793|MIM:606086|Ensembl:ENSG00000158417|HPRD:07304|
Locus tag  -
Gene type  protein-coding
Map location  2q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MFAP3L0.900.85
IL6ST0.890.91
SPG200.890.87
ERMP10.880.89
SLC12A20.880.83
ARAP20.880.87
ENDOD10.870.86
CAST0.870.89
IGSF110.870.89
CLIP40.870.82
Top 10 negatively co-expressed genes
NR2C2AP-0.51-0.48
RPL36-0.50-0.65
BCL7C-0.50-0.61
CCDC28B-0.49-0.57
LSM7-0.49-0.55
SH2B2-0.49-0.51
RPL27-0.48-0.60
RPL18-0.48-0.63
RPL35-0.48-0.59
ALKBH2-0.48-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003743translation initiation factor activityIDA10432305 
GO:0003743translation initiation factor activityNAS10200264 
GO:0003924GTPase activityIEA-
GO:0005515protein bindingIPI12569173 
GO:0005525GTP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006446regulation of translational initiationIDA10432305 
GO:0006446regulation of translational initiationNAS10200264 
GO:0006412translationIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EIF1AXEIF1A | EIF1AP1 | EIF4C | eIF-1A | eIF-4Ceukaryotic translation initiation factor 1A, X-linked-HPRD,BioGRID12514125 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-199168174m8hsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-200bc/429349355m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-2173473531Ahsa-miR-217UACUGCAUCAGGAACUGAUUGGAU
miR-4911972041A,m8hsa-miR-491brainAGUGGGGAACCCUUCCAUGAGGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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