Gene Page: PCDHA9

Summary ?
GeneID9752
SymbolPCDHA9
SynonymsPCDH-ALPHA9
Descriptionprotocadherin alpha 9
ReferenceMIM:606315|HGNC:HGNC:8675|Ensembl:ENSG00000204961|HPRD:07327|Vega:OTTHUMG00000163373
Gene typeprotein-coding
Map location5q31
Pascal p-value8.753E-6
eGeneCerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IGenome scan meta-analysisPsr: 0.0032 
ExpressionMeta-analysis of gene expressionP value: 1.517 

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ATAD10.850.84
IMMT0.840.87
STAU20.840.85
GPRASP20.840.82
CUL20.830.85
NRD10.830.85
RPS6KC10.830.82
MTMR20.830.83
PSMD10.830.85
SERAC10.830.85
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MT-CO2-0.69-0.66
AF347015.31-0.69-0.67
AF347015.21-0.68-0.64
AF347015.8-0.68-0.66
AF347015.2-0.67-0.65
AF347015.33-0.65-0.64
MT-CYB-0.65-0.63
AF347015.15-0.64-0.64
HIGD1B-0.64-0.64
AF347015.27-0.63-0.63

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIEA-
GO:0007156homophilic cell adhesionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
RODWELL AGING KIDNEY NO BLOOD UP 222139All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP 487303All SZGR 2.0 genes in this pathway
MIKKELSEN IPS HCP WITH H3 UNMETHYLATED 8050All SZGR 2.0 genes in this pathway
MIKKELSEN ES HCP WITH H3 UNMETHYLATED 6331All SZGR 2.0 genes in this pathway
MIKKELSEN MEF HCP WITH H3 UNMETHYLATED 228119All SZGR 2.0 genes in this pathway
HOLLEMAN PREDNISOLONE RESISTANCE B ALL DN 128All SZGR 2.0 genes in this pathway