Gene Page: NUAK1

Summary
GeneID  9891
Symbol  NUAK1
Synonyms  ARK5|KIAA0537
Description  NUAK family, SNF1-like kinase, 1
See related  HGNC:14311|MIM:608130|Ensembl:ENSG00000074590|HPRD:12171|
Locus tag  -
Gene type  protein-coding
Map location  12q23.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0192 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LMNB20.920.90
MCM70.910.78
MSI10.900.77
TCF30.900.79
NUMA10.900.88
AZI10.900.86
RCOR20.890.90
CDK5RAP20.890.85
DVL20.890.86
POLD10.890.83
Top 10 negatively co-expressed genes
AF347015.31-0.63-0.84
MT-CO2-0.61-0.83
AF347015.27-0.60-0.80
IFI27-0.60-0.80
C5orf53-0.60-0.68
B2M-0.60-0.76
MT-CYB-0.60-0.80
AF347015.33-0.60-0.78
FXYD1-0.59-0.79
S100B-0.59-0.76
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:0005515protein bindingIPI16306228 |17353931 
GO:0005524ATP bindingIEA-
GO:0004674protein serine/threonine kinase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
IGHA2-immunoglobulin heavy constant alpha 2 (A2m marker)Affinity Capture-MSBioGRID17353931 
KRT77K1B | KRT1B | MGC148087keratin 77Affinity Capture-MSBioGRID17353931 
PRKAR1ACAR | CNC | CNC1 | DKFZp779L0468 | MGC17251 | PKR1 | PPNAD1 | PRKAR1 | TSE1protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)Affinity Capture-MSBioGRID17353931 
PRPSAP1PAP39phosphoribosyl pyrophosphate synthetase-associated protein 1Affinity Capture-MSBioGRID17353931 
S100A860B8AG | CAGA | CFAG | CGLA | CP-10 | L1Ag | MA387 | MIF | MRP8 | NIF | P8S100 calcium binding protein A8Affinity Capture-MSBioGRID17353931 
S100A960B8AG | CAGB | CFAG | CGLB | L1AG | LIAG | MAC387 | MIF | MRP14 | NIF | P14S100 calcium binding protein A9Affinity Capture-MSBioGRID17353931 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-145101810251A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-182302030271A,m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-203.1321732231Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-22431283134m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-23299430011A,m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-30-5p276927751Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-323299430001Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-369-3p322732341A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374322832351A,m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-96302130271Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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