| 1 | Drug News Perspect. 2008 Dec 21: 581-92 |
|---|---|
| PMID | 19221639 |
| Title | New therapeutic promises in the treatment of depression and schizophrenia. |
| Abstract | The XXVI Collegium Internationale Neuro-Psychopharmacologicum (CINP) Congress, commemorating its 50th anniversary, was held in Munich, Germany, from July 13 to 17, 2008, at the Internationales Congress Center. Co-incidentally, this year Munich is also celebrating its 850th birthday and venerating various events. Keeping its tradition, the CINP Congress addressed the main issues related to mental depression, schizophrenia and anxiety disorders. The various symposia addressed topics such as immunology in psychiatry, status of conventional and atypical antipsychotics, risks and benefits in long-term use of selective serotonin reuptake inhibitors, interrelating the role of various neurotransmitters, particularly, dopamine and glutamate in psychiatry and animals models employed in central nervous system disorders. The congress also addressed educational issues such as state-of-the-art treatment of various psychiatric disorders. This was in line with the current observations of the World Health Organization (WHO) database, according to which approximately 1 billion people worldwide are battling neurological disorders ranging from migraines to epilepsy and dementia. The economic burden of both treatment and loss of social workforce is huge even though several remedies are available for the management of these disorders. Therefore, the CINP rightly addressed the issues of discovering new targets and therapeutic options in the management of neuropsychiatric disorders. The conference also brought together scientists involved in basic or clinical research. The present article summarizes the outcome of the deliberations. |
| SCZ Keywords | schizophrenia, schizophrenics |
| 2 | Int. J. Neuropsychopharmacol. 2015 Sep 18: pyv042 |
| PMID | 25899066 |
| Title | Biomarkers for Psychiatry: The Journey from Fantasy to Fact, a Report of the 2013 CINP Think Tank. |
| Abstract | A think tank sponsored by the Collegium Internationale Neuropsychopharmacologium (CINP) debated the status and prospects of biological markers for psychiatric disorders, focusing on schizophrenia and major depressive disorder. Discussions covered markers defining and predicting specific disorders or domains of dysfunction, as well as predicting and monitoring medication efficacy. Deliberations included clinically useful and viable biomarkers, why suitable markers are not available, and the need for tightly-controlled sample collection. Different types of biomarkers, appropriate sensitivity, specificity, and broad-based exploitability were discussed. Whilst a number of candidates are in the discovery phases, all will require replication in larger, real-life cohorts. Clinical cost-effectiveness also needs to be established. Since a single measure is unlikely to suffice, multi-modal strategies look more promising, although they bring greater technical and implementation complexities. Identifying reproducible, robust biomarkers will probably require pre-competitive consortia to provide the resources needed to identify, validate, and develop the relevant clinical tests. |
| SCZ Keywords | schizophrenia, schizophrenics |