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Protein-protein interaction for TRAP1
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene TRAP1
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| TRAP1 | EXT1 | - | HPRD,BioGRID | 10545594 |
| TRAP1 | TNFRSF1A | Reconstituted Complex | BioGRID | 7876093 |
| TRAP1 | EXT2 | - | HPRD,BioGRID | 10545594 |
| TRAP1 | RB1 | - | HPRD,BioGRID | 8756626 |
| TRAP1 | SF3A2 | Affinity Capture-MS | BioGRID | 12234937 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| EXT1 | CNTF | Affinity Capture-MS | BioGRID | 17353931 |
| EXT1 | OSTF1 | Affinity Capture-MS | BioGRID | 17353931 |
| TNFRSF1A | NSMAF | - | HPRD,BioGRID | 8808629 |
| TNF-R55 interacts with FAN. | BIND | 12391233 | ||
| TNFRSF1A | MOAP1 | TNF-R1 interacts with MAP-1. | BIND | 15949439 |
| TNFRSF1A | MON2 | - | HPRD | 14743216 |
| TNFRSF1A | HSPA8 | - | HPRD,BioGRID | 11909948 |
| - | HPRD | 11909948|14743216 | ||
| TNFRSF1A | RHOA | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | FANCD2 | Affinity Capture-MS | BioGRID | 14743216 |
| TNFRSF1A | IKBKG | - | HPRD,BioGRID | 10755617 |
| TNFRSF1A | CASP2 | Affinity Capture-Western | BioGRID | 8985253 |
| TNFRSF1A | HSP90AA1 | - | HPRD | 7876093 |
| TNFRSF1A | PTPN6 | - | HPRD | 11786908 |
| TNFRSF1A | BCL10 | Two-hybrid | BioGRID | 10400625 |
| TNFRSF1A | CASP7 | - | HPRD,BioGRID | 11755217 |
| TNFRSF1A | HAX1 | - | HPRD | 14743216 |
| TNFRSF1A | TRADD | Affinity Capture-Western; Two-hybrid | BioGRID | 8565075 |8612133 |8943045 |9082980 |9915703 |10187805 |
| - | HPRD | 8565075 |8612133 |10911999|8612133 |10911999 | ||
| TRADD interacts with TNFR1. | BIND | 11684708 | ||
| - | HPRD | 8612133 |10911999 | ||
| TNFR1 interacts with TRADD. This interaction was modeled on a demonstrated interaction between TNFR1 from an unspecified species and human TRADD. | BIND | 11226577 | ||
| TNFR1 interacts with TRADD. | BIND | 15247912 | ||
| TNFRSF1A | JAK1 | - | HPRD,BioGRID | 11801527 |
| TNFRSF1A | PTPN11 | - | HPRD | 11786908 |
| TNFRSF1A | IKBKB | - | HPRD,BioGRID | 10755617 |
| TNFRSF1A | BID | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | CASP10 | - | HPRD | 11098060 |
| Affinity Capture-Western; Co-purification | BioGRID | 9045686 |15659383 | ||
| TNFRSF1A | RASSF1 | TNF-R1 interacts with RASSF1A. | BIND | 15949439 |
| TNFRSF1A | CRADD | Affinity Capture-Western | BioGRID | 8985253 |
| TNFRSF1A | TRADD | Affinity Capture-Western; Two-hybrid | BioGRID | 8565075 |8612133 |8943045 |9082980 |9915703 |10187805 |
| - | HPRD | 8565075 |8612133 |10911999|8612133 |10911999 | ||
| TRADD interacts with TNFR1. | BIND | 11684708 | ||
| - | HPRD | 8612133 |10911999 | ||
| TNFR1 interacts with TRADD. This interaction was modeled on a demonstrated interaction between TNFR1 from an unspecified species and human TRADD. | BIND | 11226577 | ||
| TNFR1 interacts with TRADD. | BIND | 15247912 | ||
| TNFRSF1A | LRRC59 | - | HPRD | 14743216 |
| TNFRSF1A | HIST2H4A | - | HPRD | 14743216 |
| TNFRSF1A | PSMD2 | - | HPRD,BioGRID | 7601280 |9126987 |
| TNFRSF1A | CHUK | - | HPRD | 10755617 |
| TNFRSF1A | FASLG | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | FAS | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | CDIPT | - | HPRD | 14743216 |
| TNFRSF1A | TRADD | Affinity Capture-Western; Two-hybrid | BioGRID | 8565075 |8612133 |8943045 |9082980 |9915703 |10187805 |
| - | HPRD | 8565075 |8612133 |10911999|8612133 |10911999 | ||
| TRADD interacts with TNFR1. | BIND | 11684708 | ||
| - | HPRD | 8612133 |10911999 | ||
| TNFR1 interacts with TRADD. This interaction was modeled on a demonstrated interaction between TNFR1 from an unspecified species and human TRADD. | BIND | 11226577 | ||
| TNFR1 interacts with TRADD. | BIND | 15247912 | ||
| TNFRSF1A | DAPK1 | - | HPRD,BioGRID | 12911633 |
| TNFRSF1A | TRAF2 | - | HPRD,BioGRID | 8565075 |
| TNFRSF1A | MAPK8 | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | TRADD | Affinity Capture-Western; Two-hybrid | BioGRID | 8565075 |8612133 |8943045 |9082980 |9915703 |10187805 |
| - | HPRD | 8565075 |8612133 |10911999|8612133 |10911999 | ||
| TRADD interacts with TNFR1. | BIND | 11684708 | ||
| - | HPRD | 8612133 |10911999 | ||
| TNFR1 interacts with TRADD. This interaction was modeled on a demonstrated interaction between TNFR1 from an unspecified species and human TRADD. | BIND | 11226577 | ||
| TNFR1 interacts with TRADD. | BIND | 15247912 | ||
| TNFRSF1A | ATP2A2 | - | HPRD | 14743216 |
| TNFRSF1A | TUBB2B | - | HPRD | 14743216 |
| TNFRSF1A | ATP5A1 | - | HPRD | 14743216 |
| TNFRSF1A | ATAD3A | - | HPRD | 14743216 |
| TNFRSF1A | TRPC4AP | Affinity Capture-Western; Reconstituted Complex | BioGRID | 14585990 |
| TNFRSF1A | SUMO1 | Reconstituted Complex; Two-hybrid | BioGRID | 8906799 |10187798 |
| TNFRSF1A | MYL6 | - | HPRD | 14743216 |
| TNFRSF1A | LTB | - | HPRD,BioGRID | 7995952 |
| TNFRSF1A | TRADD | Affinity Capture-Western; Two-hybrid | BioGRID | 8565075 |8612133 |8943045 |9082980 |9915703 |10187805 |
| - | HPRD | 8565075 |8612133 |10911999|8612133 |10911999 | ||
| TRADD interacts with TNFR1. | BIND | 11684708 | ||
| - | HPRD | 8612133 |10911999 | ||
| TNFR1 interacts with TRADD. This interaction was modeled on a demonstrated interaction between TNFR1 from an unspecified species and human TRADD. | BIND | 11226577 | ||
| TNFR1 interacts with TRADD. | BIND | 15247912 | ||
| TNFRSF1A | SEC61A1 | - | HPRD | 14743216 |
| TNFRSF1A | MADD | - | HPRD,BioGRID | 9115275 |
| TNFRSF1A | RIPK3 | - | HPRD,BioGRID | 10339433 |
| TNFRSF1A | DAP | - | HPRD | 10187798 |
| TNFRSF1A | JAK2 | - | HPRD,BioGRID | 9510175 |
| TNFRSF1A | MSN | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | GNB2L1 | TNF-R55 interacts with RACK1. | BIND | 12391233 |
| - | HPRD | 12391233 | ||
| TNFRSF1A | GNB2L1 | TNF-R55 interacts with RACK1. | BIND | 12391233 |
| - | HPRD | 12391233 | ||
| TNFRSF1A | CASP8 | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | FADD | Affinity Capture-Western; Co-purification | BioGRID | 8565075 |15659383 |
| TNFRSF1A | RIPK1 | - | HPRD,BioGRID | 8612133 |
| TNFRSF1A | TNF | - | HPRD | 1331108 |2158863 |
| Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12887920 |14743216 | ||
| TNF-alpha interacts with TNFR1. | BIND | 7852363 | ||
| TNFRSF1A | HSPA8 | - | HPRD,BioGRID | 11909948 |
| - | HPRD | 11909948|14743216 | ||
| TNFRSF1A | UBE2I | - | HPRD,BioGRID | 9563508 |
| TNFRSF1A | RALBP1 | TNFR1 interacts with RIP1. | BIND | 15247912 |
| TNFRSF1A | TNFRSF10B | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | BIRC2 | Affinity Capture-Western | BioGRID | 8943045 |
| TNFRSF1A | TRADD | Affinity Capture-Western; Two-hybrid | BioGRID | 8565075 |8612133 |8943045 |9082980 |9915703 |10187805 |
| - | HPRD | 8565075 |8612133 |10911999|8612133 |10911999 | ||
| TRADD interacts with TNFR1. | BIND | 11684708 | ||
| - | HPRD | 8612133 |10911999 | ||
| TNFR1 interacts with TRADD. This interaction was modeled on a demonstrated interaction between TNFR1 from an unspecified species and human TRADD. | BIND | 11226577 | ||
| TNFR1 interacts with TRADD. | BIND | 15247912 | ||
| TNFRSF1A | GCN1L1 | - | HPRD | 14743216 |
| TNFRSF1A | TUBA3C | - | HPRD | 14743216 |
| TNFRSF1A | MRCL3 | - | HPRD | 14743216 |
| TNFRSF1A | CEP110 | Affinity Capture-Western | BioGRID | 10187805 |
| TNFRSF1A | TNF | - | HPRD | 1331108 |2158863 |
| Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12887920 |14743216 | ||
| TNF-alpha interacts with TNFR1. | BIND | 7852363 | ||
| TNFRSF1A | NSMAF | - | HPRD,BioGRID | 8808629 |
| TNF-R55 interacts with FAN. | BIND | 12391233 | ||
| TNFRSF1A | TNF | - | HPRD | 1331108 |2158863 |
| Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12887920 |14743216 | ||
| TNF-alpha interacts with TNFR1. | BIND | 7852363 | ||
| TNFRSF1A | EZR | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | STAT1 | - | HPRD,BioGRID | 10848577 |
| TNFRSF1A | TRAF1 | - | HPRD,BioGRID | 8565075 |
| TNFRSF1A | FANCI | - | HPRD | 14743216 |
| TNFRSF1A | PIP4K2B | - | HPRD,BioGRID | 9038203 |9753329 |
| TNFRSF1A | TNFSF13 | Reconstituted Complex | BioGRID | 10706119 |
| TNFRSF1A | ERAP1 | ARTS-1 interacts with TNFR1. | BIND | 12189246 |
| TNFRSF1A | NOL3 | Phenotypic Suppression | BioGRID | 9560245 |
| TNFRSF1A | RIPK2 | - | HPRD,BioGRID | 9642260 |
| TNFRSF1A | LTA | - | HPRD,BioGRID | 8387891 |
| TNFRSF1A | CASP10 | - | HPRD | 11098060 |
| Affinity Capture-Western; Co-purification | BioGRID | 9045686 |15659383 | ||
| TNFRSF1A | ARHGDIA | Co-purification | BioGRID | 15659383 |
| TNFRSF1A | GRB2 | - | HPRD,BioGRID | 10359574 |
| TNFRSF1A | ATP1A1 | - | HPRD | 14743216 |
| TNFRSF1A | TUBB6 | - | HPRD | 14743216 |
| TNFRSF1A | RPS3 | - | HPRD | 14743216 |
| TNFRSF1A | TNFSF12-TNFSF13 | - | HPRD | 10706119 |
| TNFRSF1A | BAG4 | - | HPRD,BioGRID | 9915703 |
| EXT2 | CNTF | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | GALNT5 | - | HPRD,BioGRID | 10545594 |
| EXT2 | HYOU1 | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | HNF4A | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | STK16 | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | SNCG | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | TCEB1 | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | RPS29 | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | CRB1 | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | FABP4 | Affinity Capture-MS | BioGRID | 17353931 |
| EXT2 | CLEC2L | Affinity Capture-MS | BioGRID | 17353931 |
| RB1 | RUNX2 | Runx2 interacts with pRb. | BIND | 15583032 |
| RB1 | CUX1 | - | HPRD,BioGRID | 12891711 |
| RB1 | PIK3R3 | - | HPRD,BioGRID | 12588990 |
| Rb interacts with PI3K regulatory subunit p55gamma | BIND | 12588990 | ||
| RB1 | E2F4 | Two-hybrid | BioGRID | 10869426 |
| - | HPRD | 8657117 | ||
| RB1 | LIN9 | pRb interacts with hMip130/TWIT. | BIND | 15479636 |
| - | HPRD,BioGRID | 15538385 | ||
| RB1 | BRCA1 | - | HPRD,BioGRID | 10220405 |
| BRCA1 interacts with Rb. | BIND | 10518542 | ||
| RB1 | SNAPC1 | Rb interacts with SNAP43 | BIND | 11094070 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 11094070 | ||
| RB1 | HDAC1 | RB interacts with HDAC1. | BIND | 11447271 |
| - | HPRD | 9491888 |10888886 |11896613 |11909966 | ||
| The Retinoblastoma protein interacts with Histone Deacetylase 1. | BIND | 10734134 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 9491888 |9724731 |10490602 |10615135 |10779361 |11684023 |12466959 | ||
| RB1 | AATF | - | HPRD,BioGRID | 10783144 |12450794 |
| Che-1 interacts with Rb. | BIND | 10783144 | ||
| RB1 | PPARG | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12479814 |
| RB1 | CDK6 | CDK6 phosphorylates Rb. This interaction was modeled on a demonstrated interaction between CDK6 and Rb, both from an unspecified species. | BIND | 7629134 |
| Cdk6 phosphorylates Rb | BIND | 10339564 | ||
| RB1 | EID1 | pRB interacts with EID-1. | BIND | 15949438 |
| RB1 (pRb) interacts with CRI1 (EID-1). | BIND | 15806172 | ||
| - | HPRD,BioGRID | 11073989 |11073990 | ||
| RB1 | NDC80 | - | HPRD,BioGRID | 10409732 |
| RB1 | GTF3C2 | Rb interacts with TFIIIC2 | BIND | 9169441 |
| RB1 | DNMT1 | Rb interacts with hDnmt1. | BIND | 11847125 |
| - | HPRD,BioGRID | 10888886 | ||
| RB1 | HDAC1 | RB interacts with HDAC1. | BIND | 11447271 |
| - | HPRD | 9491888 |10888886 |11896613 |11909966 | ||
| The Retinoblastoma protein interacts with Histone Deacetylase 1. | BIND | 10734134 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 9491888 |9724731 |10490602 |10615135 |10779361 |11684023 |12466959 | ||
| RB1 | CEBPE | Rb interacts with C/EBPepsilon. | BIND | 12947005 |
| RB1 | PAX6 | Reconstituted Complex | BioGRID | 10359315 |
| RB1 | CASP6 | CASP6 (caspase-6) cleaves RB-1 (hRB) at the DSID consensus site to produce the p68 form. | BIND | 15735701 |
| RB1 | CREG1 | - | HPRD,BioGRID | 9710587 |
| RB1 | RBBP7 | - | HPRD,BioGRID | 7503932 |
| The retinoblastoma protein, Rb, interacts with RbAp46. | BIND | 7503932 | ||
| RB1 | HBP1 | - | HPRD,BioGRID | 9178770 |
| RB1 | CBX1 | Reconstituted Complex | BioGRID | 12711675 |
| RB1 | FRK | - | HPRD,BioGRID | 7664264 |
| pRB interacts with Rak. | BIND | 7664264 | ||
| RB1 | CDK6 | CDK6 phosphorylates Rb. This interaction was modeled on a demonstrated interaction between CDK6 and Rb, both from an unspecified species. | BIND | 7629134 |
| Cdk6 phosphorylates Rb | BIND | 10339564 | ||
| RB1 | LIN54 | pRb interacts with hMip120. | BIND | 15479636 |
| RB1 | VDR | Reconstituted Complex | BioGRID | 11358960 |
| RB1 | ENC1 | - | HPRD,BioGRID | 9566959 |
| RB1 | SP1 | - | HPRD | 7732011 |
| Affinity Capture-Western | BioGRID | 11896613 | ||
| RB1 | MYC | - | HPRD,BioGRID | 7838535 |
| RB1 | TRIP11 | - | HPRD,BioGRID | 9256431 |
| RB1 | POLA1 | - | HPRD,BioGRID | 9395244 |
| RB1 | AHR | - | HPRD,BioGRID | 9712901 |
| RB1 | CDK4 | CDK4 phosphorylates Rb carboxy-terminus. This interaction was modelled on a demonstrated interaction between human Rb and mouse CDK4. | BIND | 15241418 |
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | CDK2 | CDK2 phosphorylates Rb carboxy-terminus. | BIND | 15241418 |
| Biochemical Activity | BioGRID | 10938106 | ||
| RB1 | RAF1 | - | HPRD,BioGRID | 9819434 |
| Raf-1 interacts with Rb. | BIND | 9819434 | ||
| RB1 | BCR | Affinity Capture-Western | BioGRID | 9071815 |
| RB1 | RBL2 | Affinity Capture-Western | BioGRID | 10490602 |
| RB1 | SNAPC3 | Rb interacts with SNAP50 | BIND | 11094070 |
| - | HPRD,BioGRID | 11094070 | ||
| RB1 | MCM7 | - | HPRD,BioGRID | 9566894 |
| MCM7 interacts with Rb. | BIND | 9566894 | ||
| RB1 | THOC1 | - | HPRD,BioGRID | 7525595 |
| RB1 | MDM2 | - | HPRD,BioGRID | 7791904|10078201 |10721693 |
| Rb interacts with Mdm2. | BIND | 15577944 | ||
| Rb interacts with MDM2. | BIND | 15485814 | ||
| RB1 | BRF1 | Affinity Capture-Western | BioGRID | 11997511 |
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | HDAC3 | - | HPRD,BioGRID | 12479814 |
| RB1 | ATF2 | - | HPRD,BioGRID | 1641004 |
| Rb interacts with ATF2. This interaction was modelled on a demonstrated interaction between Rb from an unspecified species and ATF2 from an unspecified species. | BIND | 11566021 | ||
| RB1 | SERPINB2 | - | HPRD,BioGRID | 12944478 |
| Rb interacts with PAI-2. | BIND | 12944478 | ||
| RB1 | HMGB1 | HMGB1 interacts with RB1 (pRB). This interaction was modelled on a demonstrated interaction between rat HMGB1 and human RB1 (pRB). | BIND | 11748221 |
| - | HPRD,BioGRID | 11748221 | ||
| RB1 | LIN37 | pRb interacts with hMip40. | BIND | 15479636 |
| RB1 | RBL1 | Rb interacts with the p107 promoter. | BIND | 15716956 |
| Affinity Capture-Western | BioGRID | 10490602 | ||
| RB1 | JARID1A | - | HPRD,BioGRID | 7935440 |
| Rbp2 interacts with Rb. This interaction was modeled on a demonstrated interaction between human Rbp2 and Rb from an unspecified species. | BIND | 11358960 | ||
| pRB interacts with RBP2. | BIND | 15949438 | ||
| RB1 | SPIB | - | HPRD | 10196196 |
| RB1 | JUN | - | HPRD,BioGRID | 10026157 |
| RB interacts with c-Jun. | BIND | 10026157 | ||
| RB1 | EID1 | pRB interacts with EID-1. | BIND | 15949438 |
| RB1 (pRb) interacts with CRI1 (EID-1). | BIND | 15806172 | ||
| - | HPRD,BioGRID | 11073989 |11073990 | ||
| RB1 | RFC1 | Affinity Capture-Western | BioGRID | 10353443 |
| RB1 | RBBP7 | - | HPRD,BioGRID | 7503932 |
| The retinoblastoma protein, Rb, interacts with RbAp46. | BIND | 7503932 | ||
| RB1 | SKP2 | Skp2 interacts with Rb. | BIND | 15469821 |
| RB1 | MDM2 | - | HPRD,BioGRID | 7791904|10078201 |10721693 |
| Rb interacts with Mdm2. | BIND | 15577944 | ||
| Rb interacts with MDM2. | BIND | 15485814 | ||
| RB1 | PIK3R3 | - | HPRD,BioGRID | 12588990 |
| Rb interacts with PI3K regulatory subunit p55gamma | BIND | 12588990 | ||
| RB1 | CTBP1 | - | HPRD | 11583618 |
| RB1 | RBBP8 | - | HPRD,BioGRID | 9721205 |
| RB1 | JARID1A | - | HPRD,BioGRID | 7935440 |
| Rbp2 interacts with Rb. This interaction was modeled on a demonstrated interaction between human Rbp2 and Rb from an unspecified species. | BIND | 11358960 | ||
| pRB interacts with RBP2. | BIND | 15949438 | ||
| RB1 | PRDM2 | - | HPRD,BioGRID | 7538672 |
| RB1 | MAPK9 | Rb interacts with JNK2. This interaction was modelled on a demonstrated interaction between Rb from an unspecified species and JNK2 from an unspecified species. | BIND | 11566021 |
| RB1 | HDAC2 | Affinity Capture-Western | BioGRID | 10490602 |
| RB1 | FOS | - | HPRD | 8475068 |
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | EPO | RB1 (pRB) interacts with the EPO gene 3(prime) enhancer. | BIND | 15674338 |
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | GNB2L1 | - | HPRD,BioGRID | 12761493 |
| RACK1 interacts with Rb | BIND | 12761493 | ||
| RB1 | BIRC5 | RB1 (pRB) interacts with the BIRC5 (survivin) promoter. | BIND | 15271987 |
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | CDK2 | CDK2 phosphorylates Rb carboxy-terminus. | BIND | 15241418 |
| Biochemical Activity | BioGRID | 10938106 | ||
| RB1 | PIK3R1 | Rb interacts with p55alpha | BIND | 12588990 |
| RB1 | CEBPD | C/EBP-delta interacts with Rb. | BIND | 15674331 |
| RB1 | ARNT | Affinity Capture-Western | BioGRID | 9712901 |
| RB1 | SMARCB1 | - | HPRD | 11085541 |
| RB1 | SUV39H1 | - | HPRD,BioGRID | 11484059 |11533237 |
| RB1 | CCNT2 | - | HPRD,BioGRID | 12037672 |
| RB1 | MT1G | RB1 interacts with the MT1G promoter. | BIND | 15735762 |
| RB1 | VEGFA | RB1 (pRB) interacts with the VEGF promoter. | BIND | 15674338 |
| RB1 | MNAT1 | - | HPRD,BioGRID | 11113200 |
| RB1 | EID1 | pRB interacts with EID-1. | BIND | 15949438 |
| RB1 (pRb) interacts with CRI1 (EID-1). | BIND | 15806172 | ||
| - | HPRD,BioGRID | 11073989 |11073990 | ||
| RB1 | E2F2 | E2F-2 interacts with pRb. | BIND | 8246996 |
| - | HPRD,BioGRID | 12502741 | ||
| E2F1 interacts with pRb. | BIND | 8246996 | ||
| pRB interacts with E2F-2. | BIND | 15949438 | ||
| RB1 | E2F2 | E2F-2 interacts with pRb. | BIND | 8246996 |
| - | HPRD,BioGRID | 12502741 | ||
| E2F1 interacts with pRb. | BIND | 8246996 | ||
| pRB interacts with E2F-2. | BIND | 15949438 | ||
| RB1 | TFDP1 | Affinity Capture-Western | BioGRID | 7739537 |
| RB1 | TMPO | Rb interacts with LAP2alpha | BIND | 12475961 |
| - | HPRD,BioGRID | 12475961 | ||
| RB1 | DNMT1 | Rb interacts with hDnmt1. | BIND | 11847125 |
| - | HPRD,BioGRID | 10888886 | ||
| RB1 | CASP2 | CASP2 (caspase-2) cleaves RB-1 (hRB) at the DEAD consensus site into the p100 form. | BIND | 15735701 |
| RB1 | SMARCA4 | - | HPRD,BioGRID | 7923370 |
| RB1 | SP1 | - | HPRD | 7732011 |
| Affinity Capture-Western | BioGRID | 11896613 | ||
| RB1 | HDAC1 | RB interacts with HDAC1. | BIND | 11447271 |
| - | HPRD | 9491888 |10888886 |11896613 |11909966 | ||
| The Retinoblastoma protein interacts with Histone Deacetylase 1. | BIND | 10734134 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 9491888 |9724731 |10490602 |10615135 |10779361 |11684023 |12466959 | ||
| RB1 | MCM7 | - | HPRD,BioGRID | 9566894 |
| MCM7 interacts with Rb. | BIND | 9566894 | ||
| RB1 | CASP9 | CASP9 (caspase-9) cleaves RB-1 (hRB) at the LEND consensus site to produce the p76 form. | BIND | 15735701 |
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | RAF1 | - | HPRD,BioGRID | 9819434 |
| Raf-1 interacts with Rb. | BIND | 9819434 | ||
| RB1 | ARID3B | - | HPRD,BioGRID | 10446990 |
| RB1 | PA2G4 | - | HPRD,BioGRID | 11268000 |
| RB1 | HSPA8 | - | HPRD | 7673249 |
| RB1 | MORF4L1 | - | HPRD,BioGRID | 11500496 |12397079 |
| RB1 | KAT2B | pRb interacts with the acetyltransferase domain of P/CAF. | BIND | 15044952 |
| RB1 | PML | - | HPRD,BioGRID | 9448006 |
| RB1 | CASP10 | CASP10 (caspase-10) cleaves RB-1 (hRB) at the DSID consensus site to produce the p68 form. | BIND | 15735701 |
| RB1 | PRKRA | - | HPRD,BioGRID | 9010216 |
| RB1 | CDKN1A | Rb interacts with the p21 promoter. | BIND | 15716956 |
| RB1 | CCND1 | Rb interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between Cyclin D1 from mouse and Rb from human. | BIND | 11126356 |
| - | HPRD,BioGRID | 8490963 | ||
| RB1 | E4F1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 10869426 |
| RB1 | CCND3 | Two-hybrid | BioGRID | 17972097 |
| RB1 | BRD8 | pRB interacts with BRD8 promoter. | BIND | 15949438 |
| RB1 | E2F2 | E2F-2 interacts with pRb. | BIND | 8246996 |
| - | HPRD,BioGRID | 12502741 | ||
| E2F1 interacts with pRb. | BIND | 8246996 | ||
| pRB interacts with E2F-2. | BIND | 15949438 | ||
| RB1 | NFIX | Affinity Capture-Western | BioGRID | 11896613 |
| RB1 | PPIA | Rb interacts with CypA. | BIND | 12210730 |
| RB1 | AR | Rb interacts with AR. | BIND | 9675141 |
| - | HPRD,BioGRID | 9675141 | ||
| RB1 | SP3 | - | HPRD | 7732011 |
| RB1 | BGLAP | pRB interacts with OC promoter. | BIND | 15949438 |
| RB1 | LIN9 | pRb interacts with hMip130/TWIT. | BIND | 15479636 |
| - | HPRD,BioGRID | 15538385 | ||
| RB1 | ELF1 | - | HPRD | 8493578 |
| RB1 | TYR | Rb interacts with the TYR promoter. | BIND | 15716956 |
| RB1 | DNMT3A | Reconstituted Complex | BioGRID | 11350943 |
| RB1 | CBX5 | Affinity Capture-Western | BioGRID | 11484059 |
| RB1 | BRCA1 | - | HPRD,BioGRID | 10220405 |
| BRCA1 interacts with Rb. | BIND | 10518542 | ||
| RB1 | TP73 | Affinity Capture-Western | BioGRID | 12761493 |
| RB1 | RING1 | - | HPRD,BioGRID | 11583618 |
| RB1 | ARID4A | - | HPRD,BioGRID | 10321733 |10490602 |
| RB1 | HMGB1 | HMGB1 interacts with RB1 (pRB). This interaction was modelled on a demonstrated interaction between rat HMGB1 and human RB1 (pRB). | BIND | 11748221 |
| - | HPRD,BioGRID | 11748221 | ||
| RB1 | LMNA | - | HPRD,BioGRID | 8058329 |8278403 |
| Rb interacts with lamin C | BIND | 12475961 | ||
| RB1 | MRFAP1 | Affinity Capture-Western; Co-purification | BioGRID | 11500496 |12397079 |
| RB1 | RBL1 | Rb interacts with the p107 promoter. | BIND | 15716956 |
| Affinity Capture-Western | BioGRID | 10490602 | ||
| RB1 | BRD2 | pRB interacts with BRD2 promoter. | BIND | 15949438 |
| RB1 | JUN | - | HPRD,BioGRID | 10026157 |
| RB interacts with c-Jun. | BIND | 10026157 | ||
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | SNW1 | Reconstituted Complex | BioGRID | 12466551 |
| RB1 | CASP7 | CASP7 (caspase-7) cleaves RB-1 (hRB) at the DEAD and DSID consensus sites to produce the p68, p61 and p48 forms. | BIND | 15735701 |
| RB1 | CCND1 | Rb interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between Cyclin D1 from mouse and Rb from human. | BIND | 11126356 |
| - | HPRD,BioGRID | 8490963 | ||
| RB1 | NCOA6 | Rb interacts with ASC-2. | BIND | 14645241 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 14645241 | ||
| RB1 | E2F1 | pRB interacts with E2F-1. | BIND | 15949438 |
| pRB interacts with E2F1. | BIND | 8816797 |8816798 | ||
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 7739537 |8230483 |8896460 |9422723 |10869426 |11470869 |12397079 | ||
| pRb interacts with E2F1. | BIND | 15619620 | ||
| E2F1 (RBP3) interacts with pRB. | BIND | 1638634 | ||
| - | HPRD | 1388726 |11583618 | ||
| Rb interacts with E2F-1. | BIND | 8346196 | ||
| Rb interacts with E2F | BIND | 9632788 | ||
| RB1 | SNAPC1 | Rb interacts with SNAP43 | BIND | 11094070 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 11094070 | ||
| RB1 | CASP3 | CASP3 (caspase-3) cleaves RB-1 (hRB) at the DEAD and DSID consensus sites to produce the p100, p68, p61 and p48 forms. | BIND | 15735701 |
| RB1 | HIF1A | RB1 (pRB) interacts with HIF1A (HIF-1-alpha). | BIND | 15674338 |
| RB1 | ABL1 | - | HPRD | 7828850 |8242749 |
| Rb interacts with c-Abl | BIND | 9632788 | ||
| - | HPRD,BioGRID | 8242749 | ||
| RB1 | RBAK | - | HPRD | 10702291 |
| RB1 | MITF | An unspecified isoform of Mitf interacts with Rb. | BIND | 15716956 |
| RB1 | MAPK1 | RB1 is phosphorylated by MAPK1. This interaction was modeled on a demonstrated interaction between human KIAA1536 and MAPK1 from an unspecified species. | BIND | 15489336 |
| RB1 | RBBP5 | - | HPRD,BioGRID | 7558034 |
| RB1 | E2F2 | E2F-2 interacts with pRb. | BIND | 8246996 |
| - | HPRD,BioGRID | 12502741 | ||
| E2F1 interacts with pRb. | BIND | 8246996 | ||
| pRB interacts with E2F-2. | BIND | 15949438 | ||
| RB1 | TMPO | Rb interacts with LAP2alpha | BIND | 12475961 |
| - | HPRD,BioGRID | 12475961 | ||
| RB1 | AATF | - | HPRD,BioGRID | 10783144 |12450794 |
| Che-1 interacts with Rb. | BIND | 10783144 | ||
| RB1 | PELP1 | - | HPRD,BioGRID | 12682072 |
| PELP1 interacts with pRb. | BIND | 12682072 | ||
| RB1 | UBTF | - | HPRD,BioGRID | 11042686 |
| RB1 | ABL1 | - | HPRD | 7828850 |8242749 |
| Rb interacts with c-Abl | BIND | 9632788 | ||
| - | HPRD,BioGRID | 8242749 | ||
| RB1 | TAF1 | TAFII250 interacts with Rb. | BIND | 11126356 |
| - | HPRD,BioGRID | 7724524 |9242374 |9858607 | ||
| RB1 | ATF2 | - | HPRD,BioGRID | 1641004 |
| Rb interacts with ATF2. This interaction was modelled on a demonstrated interaction between Rb from an unspecified species and ATF2 from an unspecified species. | BIND | 11566021 | ||
| RB1 | MDM4 | pRb interacts with MDMX. This interaction was modeled on a demonstrated interaction between mouse MDMX and human pRb. | BIND | 12532331 |
| RB1 | FRK | - | HPRD,BioGRID | 7664264 |
| pRB interacts with Rak. | BIND | 7664264 | ||
| RB1 | ZBTB16 | pRB interacts with PLZF. | BIND | 15949438 |
| RB1 | SNAPC3 | Rb interacts with SNAP50 | BIND | 11094070 |
| - | HPRD,BioGRID | 11094070 | ||
| RB1 | MYOD1 | - | HPRD,BioGRID | 8381715 |
| RB1 | GNB2L1 | - | HPRD,BioGRID | 12761493 |
| RACK1 interacts with Rb | BIND | 12761493 | ||
| RB1 | RBBP9 | - | HPRD,BioGRID | 9697699 |
| RB1 | CCNA1 | - | HPRD,BioGRID | 10022926 |
| RB1 | CASP8 | CASP8 (caspase-8) cleaves RB-1 (hRB) into the p68 form and to a lesser extent the p61 form. | BIND | 15735701 |
| RB1 | NCOA6 | Rb interacts with ASC-2. | BIND | 14645241 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 14645241 | ||
| RB1 | TAF1 | TAFII250 interacts with Rb. | BIND | 11126356 |
| - | HPRD,BioGRID | 7724524 |9242374 |9858607 | ||
| RB1 | HDAC1 | RB interacts with HDAC1. | BIND | 11447271 |
| - | HPRD | 9491888 |10888886 |11896613 |11909966 | ||
| The Retinoblastoma protein interacts with Histone Deacetylase 1. | BIND | 10734134 | ||
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 9491888 |9724731 |10490602 |10615135 |10779361 |11684023 |12466959 | ||
| RB1 | TGM2 | - | HPRD,BioGRID | 9315663 |
| RB1 | PHB | - | HPRD,BioGRID | 10376528 |
| RB1 | TFDP2 | Affinity Capture-Western | BioGRID | 7739537 |
| RB1 | AR | Rb interacts with AR. | BIND | 9675141 |
| - | HPRD,BioGRID | 9675141 | ||
| RB1 | LMNA | - | HPRD,BioGRID | 8058329 |8278403 |
| Rb interacts with lamin C | BIND | 12475961 | ||
| RB1 | BDP1 | Rb interacts with TFIIIB90 | BIND | 9169441 |
| RB1 | RBBP4 | The retinoblastoma protein 1 (Rb) interacts with RbAp48 | BIND | 7503932 |
| - | HPRD,BioGRID | 7503932 | ||
| RB1 | PELP1 | - | HPRD,BioGRID | 12682072 |
| PELP1 interacts with pRb. | BIND | 12682072 | ||
| RB1 | TBP | Rb interacts with TBP | BIND | 11094070 |
| RB1 | BNC2 | pRB interacts with BAA90908. | BIND | 15949438 |
| RB1 | RBBP4 | The retinoblastoma protein 1 (Rb) interacts with RbAp48 | BIND | 7503932 |
| - | HPRD,BioGRID | 7503932 | ||
| RB1 | ABL1 | - | HPRD | 7828850 |8242749 |
| Rb interacts with c-Abl | BIND | 9632788 | ||
| - | HPRD,BioGRID | 8242749 | ||
| RB1 | SERPINB2 | - | HPRD,BioGRID | 12944478 |
| Rb interacts with PAI-2. | BIND | 12944478 | ||
| RB1 | MDM2 | - | HPRD,BioGRID | 7791904|10078201 |10721693 |
| Rb interacts with Mdm2. | BIND | 15577944 | ||
| Rb interacts with MDM2. | BIND | 15485814 | ||
| RB1 | BAG1 | Affinity Capture-Western | BioGRID | 12845674 |
| RB1 | CDK9 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12037672 |
| RB1 | JARID1A | - | HPRD,BioGRID | 7935440 |
| Rbp2 interacts with Rb. This interaction was modeled on a demonstrated interaction between human Rbp2 and Rb from an unspecified species. | BIND | 11358960 | ||
| pRB interacts with RBP2. | BIND | 15949438 | ||
| RB1 | UBE2I | RB1 (pRb) interacts with, and is sumoylated by, an unspecified isoform of UBE2I (Ubc9). | BIND | 15806172 |
| RB1 | E2F4 | Two-hybrid | BioGRID | 10869426 |
| - | HPRD | 8657117 | ||
| RB1 | MORF4L2 | - | HPRD,BioGRID | 14506250 |
| RB1 | CEBPB | - | HPRD,BioGRID | 11596110 |
| RB1 | CBX4 | - | HPRD,BioGRID | 11583618 |
| SF3A2 | CHERP | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | HSPD1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3B1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3B4 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SNRPD3 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | HTATSF1 | - | HPRD,BioGRID | 9710584 |
| SF3A2 | SNRPD1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3A1 | SF3a66 interacts with SF3a120. | BIND | 11533230 |
| Affinity Capture-MS | BioGRID | 12234937 | ||
| SF3A2 | SNRPB2 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3B5 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3A1 | SF3a66 interacts with SF3a120. | BIND | 11533230 |
| Affinity Capture-MS | BioGRID | 12234937 | ||
| SF3A2 | DDX46 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 12234937 |
| SF3A2 | U2AF2 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3B14 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | RBM17 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | PHF5A | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SNRPE | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | U2AF1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SNRPA1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | DDX42 | Affinity Capture-Western | BioGRID | 12234937 |
| SF3A2 | SNRPB | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | PUF60 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3A3 | Affinity Capture-MS | BioGRID | 12234937 |
| - | HPRD | 8022796 |11533230 | ||
| SF3A2 | SNRPG | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | HMG20B | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SR140 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SNRPF | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3B3 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3A3 | Affinity Capture-MS | BioGRID | 12234937 |
| - | HPRD | 8022796 |11533230 | ||
| SF3A2 | SMNDC1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | DNAJC8 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SF3B2 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | RETN | - | HPRD | 8211113 |
| SF3A2 | SFRS1 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | DHX15 | Affinity Capture-MS | BioGRID | 12234937 |
| SF3A2 | SNRPD2 | Affinity Capture-MS | BioGRID | 12234937 |
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