|
Gene set name (Click to find documents) |
Method | No. of genes (Click to find gene list) |
Reference |
---|---|---|---|
SZ-SNPs from GWAS Catalog | Curation from literation | 561 SNPs in XX genes | GWAS Catalogy |
PGC significant SNPs | GWAS | 128 SNPs, involved in 750 genes (+35/-10kb) | Psychiatric Genomics Consortium (PGC) |
SZ-SNPs collected from GWASdb | GWAS | 2537 SNPs, in XX genes | GWASdb |
De novo mutations | Manual collection of next-generation sequencing studies | 302 genes | PubMed |
Association | A combined odds ratio method (Sun et al. 2008), association studies | 281 | SchizophreniaGene Database |
GSMA_I | genome scan meta-analysis | 2155 | Lewis et al. (2003) Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia. The American Journal of Human Genetics 73(1): 34 - 48 PubMed |
GSMA_IIA | genome scan meta-analysis (All samples) | 2295 | Ng et al. (2008) Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Molecular Psychiatry: 1 - 12 |
GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | 1474 | Ng et al. (2008) Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Molecular Psychiatry: 1 - 12 |
Literature | High-throughput literature-search | 1682 | PubMed |
Expression | Expression | 726 | The Stanley Medical Research Institute Online Genomics Database |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | 1947 | Gene Ontoloty |
Network | Shortest path distance of core genes in the Human protein-protein interaction network | 1035 | Wu et al. (2008). Network-based global inference of human disease genes. Mol Syst Biol 4 PubMed |
Core genes | Manual collection | 38 | Ross et al. (2006) Neurobiology of schizophrenia. Neuron. 52(1): 139-53 PubMed Allen et al. (2008) Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat. Genet. 40: 827 - 834 PubMed |
75 genes by COR | Gene ranking | 75 | Sun et al. (2008) Candidate genes for schizophrenia: a survey of association studies and gene ranking. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B: 1173-1181 PubMed |
160 by Lewis et al. | Gene ranking using optimal weight matrix | 160 | Sun et al. (2009) Bioinformatics: accepted with minor revision |
173 by Ng et al. | Gene ranking | 173 | Sun et al. (2009) Bioinformatics: accepted with minor revision |
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