Schizophrenia Gene Resource (SZGR) provides a comprehensive online resource for schizophrenia genetics studies. SZGR also provides an online candidate gene ranking tool to help the user prioritize candidate genes by pre-optimized or custom weight schemes. Since 2009, we have been maintaining and updating this SZ gene resource to the community. Feed back please send email to us. Click here for a summary table of all gene sets. Data summary and updates can be found here. Currently, SZGR collected and integrated genes related to schizophrenia from the following data sources and annotations:

large-scale GWA studies (e.g., PGC) SZ-associated SNPs from GWAS Catalog, GWASdb brain related annotation data from ENCODE, RoadMap, FANTOM5, eQTL, RegulomeDB association studies linkage analysis general gene expression spatial and temporal brain expression data from BRAINATLAS literature search Gene Ontology annotations protein-protein interaction networks KEGG pathways microRNAs and their target sites.

• As of 12/20/2015, annotation from RegulomeDB, RoadMap, ENCODE, and FANTOM5 were included.
• In 07/21/2015, schizophrenia related SNPs from GWAS Catalog were included. Additional annotation such as enhancer, promoter, and gene expression is now available.
• In 06/18/2015, we added spatiotemporal brain expression data from BRAINSPAN. We now allow users to search for gene expression. We also integrated visualization tools for gene co-expression distribution.
• In 03/20/2015, we annotated PGC2 SNPs using enhancer and promoter from RoadMap brain samples. We combined the following samples for brain tissues:
  • E071 Brain Hippocampus
  • E074 Brain Substantia Nigra
  • E068 Brain Anterior Caudate
  • E069 Brain Cingulate Gyrus
  • E072 Brain Inferior Temporal Lobe
  • E067 Brain Angular Gyrus
  • E073 Brain_Dorsolateral_Prefrontal_Cortex
  • E082 Fetal Brain Female
  • E081 Fetal Brain Male
• In December 28, 2014, PGC2 significant SNPs were included in SZGR.

• Core gene list
• 75 genes by COR
• 160 by Lewis et al.
• 173 by Ng et al.