 |
||||||
|
|
||||||
Protein-protein interaction for CHEK2
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene CHEK2
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| CHEK2 | MUS81 | - | HPRD,BioGRID | 11741546 |
| CHEK2 | DBF4 | - | HPRD,BioGRID | 12441400 |
| CHEK2 | MDC1 | - | HPRD,BioGRID | 12551934 |12607004 |
| CHEK2 | RAD50 | Affinity Capture-Western | BioGRID | 17525332 |
| CHEK2 | TSSK1B | - | HPRD | 12556502 |
| CHEK2 | BRCA2 | Affinity Capture-Western | BioGRID | 17525332 |
| CHEK2 | ATM | ATM phosphorylates Chk2 at threonine 68. | BIND | 15790808 |
| ATM phosphorylates Chk2 at threonine 68. | BIND | 15064416 | ||
| CHEK2 | RAD9A | - | HPRD | 12049741 |
| CHEK2 | MRC1 | - | HPRD | 11715017 |
| CHEK2 | BRCA1 | - | HPRD,BioGRID | 10724175 |
| CHEK2 | PLK1 | - | HPRD,BioGRID | 12493754 |
| CHEK2 | TP53BP1 | Affinity Capture-Western | BioGRID | 17525332 |
| CHEK2 | MSH2 | - | HPRD,BioGRID | 12447371 |
| CHEK2 | VCP | Affinity Capture-Western | BioGRID | 17525332 |
| CHEK2 | ATMIN | ASCIZ interacts with an unspecified isoform of CHK2. | BIND | 15933716 |
| CHEK2 | GINS2 | Affinity Capture-Western | BioGRID | 17525332 |
| CHEK2 | PLK3 | - | HPRD,BioGRID | 12242661 |
| CHEK2 | ERCC6 | - | HPRD | 9450932 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| MUS81 | EME1 | - | HPRD,BioGRID | 12721304 |
| DBF4 | MCM4 | Two-hybrid | BioGRID | 12614612 |
| DBF4 | CDC7 | - | HPRD | 10373557|10523313 |12614612 |
| HsCdc7 interacts with HsDbf4. | BIND | 10523313 | ||
| Affinity Capture-Western; in vivo; Reconstituted Complex; Two-hybrid | BioGRID | 10373557 |10523313 |12614612 | ||
| DBF4 | CDC7 | - | HPRD | 10373557|10523313 |12614612 |
| HsCdc7 interacts with HsDbf4. | BIND | 10523313 | ||
| Affinity Capture-Western; in vivo; Reconstituted Complex; Two-hybrid | BioGRID | 10373557 |10523313 |12614612 | ||
| DBF4 | LSM8 | Two-hybrid | BioGRID | 15231747 |
| DBF4 | MCM2 | - | HPRD,BioGRID | 12614612 |
| DBF4 | MEN1 | Menin interacts with ASK. | BIND | 15374998 |
| DBF4 | ORC1L | Two-hybrid | BioGRID | 12614612 |
| DBF4 | ORC4L | Affinity Capture-Western | BioGRID | 12614612 |
| DBF4 | ORC5L | Two-hybrid | BioGRID | 12614612 |
| DBF4 | CDC7 | - | HPRD | 10373557|10523313 |12614612 |
| HsCdc7 interacts with HsDbf4. | BIND | 10523313 | ||
| Affinity Capture-Western; in vivo; Reconstituted Complex; Two-hybrid | BioGRID | 10373557 |10523313 |12614612 | ||
| DBF4 | MCM3 | - | HPRD,BioGRID | 12614612 |
| DBF4 | ORC2L | - | HPRD,BioGRID | 12614612 |
| DBF4 | MCM7 | - | HPRD,BioGRID | 12614612 |
| DBF4 | ORC6L | Affinity Capture-Western; Two-hybrid | BioGRID | 12614612 |
| MDC1 | GATA4 | Protein-peptide | BioGRID | 14578343 |
| MDC1 | TP53 | - | HPRD,BioGRID | 14519663 |
| MDC1 | HDAC8 | Protein-peptide | BioGRID | 14578343 |
| MDC1 | H2AFX | - | HPRD,BioGRID | 12607005 |14519663 |
| MDC1 | NBN | - | HPRD,BioGRID | 12607003 |12607005 |14519663 |
| MDC1 | MRE11A | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 14519663 |
| MDC1 | CENPC1 | Protein-peptide | BioGRID | 14578343 |
| MDC1 | HDAC10 | Protein-peptide | BioGRID | 14578343 |
| MDC1 | SMC1A | - | HPRD | 12607005 |
| MDC1 | POLR2A | Protein-peptide | BioGRID | 14578343 |
| MDC1 | MDM2 | Protein-peptide | BioGRID | 14578343 |
| MDC1 | WRN | Protein-peptide | BioGRID | 14578343 |
| RAD50 | MLH1 | Co-purification | BioGRID | 10783165 |
| RAD50 | TERF2IP | - | HPRD,BioGRID | 15100233 |
| RAD50 | BLM | Co-purification | BioGRID | 10783165 |
| RAD50 | MRE11A | Mre11 interacts with Rad50 | BIND | 9590181 |
| - | HPRD | 8756642 |10888888 | ||
| Affinity Capture-Western; Co-purification | BioGRID | 8756642 |9705271 |10783165 |11504724 | ||
| RAD50 | MRE11A | Mre11 interacts with Rad50 | BIND | 9590181 |
| - | HPRD | 8756642 |10888888 | ||
| Affinity Capture-Western; Co-purification | BioGRID | 8756642 |9705271 |10783165 |11504724 | ||
| RAD50 | RINT1 | - | HPRD,BioGRID | 11096100 |
| RAD50 | MSH6 | Co-purification | BioGRID | 10783165 |
| RAD50 | NBN | Affinity Capture-Western; Co-purification | BioGRID | 9705271 |10783165 |11238951 |12679336 |
| NBS1 interacts with RAD50. | BIND | 15758953 | ||
| - | HPRD | 9705271 |10426999 |11238951 | ||
| RAD50 | H2AFX | Co-localization | BioGRID | 10959836 |
| RAD50 | NBN | Affinity Capture-Western; Co-purification | BioGRID | 9705271 |10783165 |11238951 |12679336 |
| NBS1 interacts with RAD50. | BIND | 15758953 | ||
| - | HPRD | 9705271 |10426999 |11238951 | ||
| RAD50 | TERF2 | - | HPRD,BioGRID | 10888888 |
| RAD50 | MRE11A | Mre11 interacts with Rad50 | BIND | 9590181 |
| - | HPRD | 8756642 |10888888 | ||
| Affinity Capture-Western; Co-purification | BioGRID | 8756642 |9705271 |10783165 |11504724 | ||
| RAD50 | RFC1 | Co-purification | BioGRID | 10783165 |
| RAD50 | HNF4A | Affinity Capture-MS | BioGRID | 17353931 |
| RAD50 | NBN | Affinity Capture-Western; Co-purification | BioGRID | 9705271 |10783165 |11238951 |12679336 |
| NBS1 interacts with RAD50. | BIND | 15758953 | ||
| - | HPRD | 9705271 |10426999 |11238951 | ||
| TSSK1B | TGFBR1 | T-beta-RI interacts with STK22D. This interaction was modeled on a demonstrated interaction between human T-beta-RI and mouse STK22D. | BIND | 15761153 |
| TSSK1B | TGFBR2 | T-beta-RII interacts with STK22D. This interaction was modeled on a demonstrated interaction between human T-beta-RII and mouse STK22D. | BIND | 15761153 |
| BRCA2 | BRCC3 | Affinity Capture-MS; Affinity Capture-Western; Co-purification | BioGRID | 14636569 |
| BRCA2 | FANCD2 | Affinity Capture-Western; Co-localization; Two-hybrid | BioGRID | 15115758 |15199141 |
| FANCD2 interacts with BRCA2. | BIND | 15115758 | ||
| BRCA2 | C11orf30 | - | HPRD,BioGRID | 14651845 |
| BRCA2 | BCCIP | - | HPRD,BioGRID | 11313963 |
| BRCA2 | BRE | Affinity Capture-MS; Affinity Capture-Western; Co-purification | BioGRID | 14636569 |
| BRCA2 | FLNA | - | HPRD,BioGRID | 11602572 |
| BRCA2 interacts with hsFLNa. | BIND | 11602572 | ||
| BRCA2 | RAD51 | Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid | BioGRID | 9126738 |9405383 |9523196 |9560268 |9774970 |9811893 |11313963 |11477095 |12408834 |12442171 |12815053 |14580352 |14636569 |15065660 |
| - | HPRD | 9126738 |12619154 | ||
| BRCA2 interacts with RAD51. | BIND | 9774970 | ||
| BRCA2 interacts with Rad51. | BIND | 9774970 | ||
| BRCA2 interacts with an unspecified isoform of RAD51. | BIND | 15800615 | ||
| BRCA2 | FANCG | Affinity Capture-Western; Two-hybrid | BioGRID | 12915460 |
| FANCG interacts with BRCA2. | BIND | 12915460 | ||
| BRCA2 | ATR | Protein-peptide | BioGRID | 10608806 |
| BRCA2 | SMAD2 | Affinity Capture-Western | BioGRID | 12165866 |
| BRCA2 | BUB1B | - | HPRD,BioGRID | 10749118 |
| BRCA2 | FANCE | Affinity Capture-Western | BioGRID | 15199141 |
| BRCA2 | KAT2B | - | HPRD,BioGRID | 9824164 |
| BRCA2 | RAD51 | Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid | BioGRID | 9126738 |9405383 |9523196 |9560268 |9774970 |9811893 |11313963 |11477095 |12408834 |12442171 |12815053 |14580352 |14636569 |15065660 |
| - | HPRD | 9126738 |12619154 | ||
| BRCA2 interacts with RAD51. | BIND | 9774970 | ||
| BRCA2 interacts with Rad51. | BIND | 9774970 | ||
| BRCA2 interacts with an unspecified isoform of RAD51. | BIND | 15800615 | ||
| BRCA2 | SHFM1 | - | HPRD,BioGRID | 10373512 |12228710 |
| BRCA2 | FLNA | - | HPRD,BioGRID | 11602572 |
| BRCA2 interacts with hsFLNa. | BIND | 11602572 | ||
| BRCA2 | FANCG | Affinity Capture-Western; Two-hybrid | BioGRID | 12915460 |
| FANCG interacts with BRCA2. | BIND | 12915460 | ||
| BRCA2 | STAT5A | - | HPRD,BioGRID | 12459499 |
| BRCA2 | FANCD2 | Affinity Capture-Western; Co-localization; Two-hybrid | BioGRID | 15115758 |15199141 |
| FANCD2 interacts with BRCA2. | BIND | 15115758 | ||
| BRCA2 | HMG20B | - | HPRD,BioGRID | 11207365 |
| BRCA2 | RAD51 | Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid | BioGRID | 9126738 |9405383 |9523196 |9560268 |9774970 |9811893 |11313963 |11477095 |12408834 |12442171 |12815053 |14580352 |14636569 |15065660 |
| - | HPRD | 9126738 |12619154 | ||
| BRCA2 interacts with RAD51. | BIND | 9774970 | ||
| BRCA2 interacts with Rad51. | BIND | 9774970 | ||
| BRCA2 interacts with an unspecified isoform of RAD51. | BIND | 15800615 | ||
| BRCA2 | BARD1 | Co-purification; Reconstituted Complex | BioGRID | 14636569 |
| BRCA2 | RAD51 | Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid | BioGRID | 9126738 |9405383 |9523196 |9560268 |9774970 |9811893 |11313963 |11477095 |12408834 |12442171 |12815053 |14580352 |14636569 |15065660 |
| - | HPRD | 9126738 |12619154 | ||
| BRCA2 interacts with RAD51. | BIND | 9774970 | ||
| BRCA2 interacts with Rad51. | BIND | 9774970 | ||
| BRCA2 interacts with an unspecified isoform of RAD51. | BIND | 15800615 | ||
| BRCA2 | RAD51 | Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid | BioGRID | 9126738 |9405383 |9523196 |9560268 |9774970 |9811893 |11313963 |11477095 |12408834 |12442171 |12815053 |14580352 |14636569 |15065660 |
| - | HPRD | 9126738 |12619154 | ||
| BRCA2 interacts with RAD51. | BIND | 9774970 | ||
| BRCA2 interacts with Rad51. | BIND | 9774970 | ||
| BRCA2 interacts with an unspecified isoform of RAD51. | BIND | 15800615 | ||
| BRCA2 | RPA1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12527904 |
| BRCA2 | SMAD3 | SMAD3 interacts with BRCA2. | BIND | 12165866 |
| - | HPRD,BioGRID | 12165866 | ||
| BRCA2 | SMAD3 | SMAD3 interacts with BRCA2. | BIND | 12165866 |
| - | HPRD,BioGRID | 12165866 | ||
| BRCA2 | TP53 | - | HPRD,BioGRID | 9811893 |
| ATM | NBN | Co-purification; Protein-peptide | BioGRID | 10608806 |10783165 |
| NBS1 interacts with ATM. | BIND | 15758953 | ||
| ATM | CHEK1 | Protein-peptide | BioGRID | 10608806 |
| ATM | ATR | Protein-peptide | BioGRID | 10608806 |
| ATM | TP53 | - | HPRD,BioGRID | 9843217 |
| ATM phosphorylates p53 at serine 15. | BIND | 15064416 | ||
| An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species. | BIND | 15916964 | ||
| ATM phosphorylates p53 at Ser15. | BIND | 15175154 | ||
| ATM phosphorylates p53 at serine 15. | BIND | 15790808 | ||
| ATM | HINT1 | - | HPRD | 7644499 |
| ATM | TP53 | - | HPRD,BioGRID | 9843217 |
| ATM phosphorylates p53 at serine 15. | BIND | 15064416 | ||
| An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species. | BIND | 15916964 | ||
| ATM phosphorylates p53 at Ser15. | BIND | 15175154 | ||
| ATM phosphorylates p53 at serine 15. | BIND | 15790808 | ||
| ATM | TERF1 | - | HPRD,BioGRID | 11375976 |
| ATM | RAD51 | Affinity Capture-Western | BioGRID | 10212258 |
| ATM | TP53 | - | HPRD,BioGRID | 9843217 |
| ATM phosphorylates p53 at serine 15. | BIND | 15064416 | ||
| An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species. | BIND | 15916964 | ||
| ATM phosphorylates p53 at Ser15. | BIND | 15175154 | ||
| ATM phosphorylates p53 at serine 15. | BIND | 15790808 | ||
| ATM | TP53 | - | HPRD,BioGRID | 9843217 |
| ATM phosphorylates p53 at serine 15. | BIND | 15064416 | ||
| An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species. | BIND | 15916964 | ||
| ATM phosphorylates p53 at Ser15. | BIND | 15175154 | ||
| ATM phosphorylates p53 at serine 15. | BIND | 15790808 | ||
| ATM | TP53 | - | HPRD,BioGRID | 9843217 |
| ATM phosphorylates p53 at serine 15. | BIND | 15064416 | ||
| An unspecified isoform of ATM interacts with and phosphorylates p53. This interaction was modeled on a demonstrated interaction between human ATM and p53 from an unspecified species. | BIND | 15916964 | ||
| ATM phosphorylates p53 at Ser15. | BIND | 15175154 | ||
| ATM phosphorylates p53 at serine 15. | BIND | 15790808 | ||
| ATM | RHEB | Affinity Capture-Western; Reconstituted Complex | BioGRID | 15854902 |
| ATM interacts with Rheb. | BIND | 15854902 | ||
| ATM | BLM | Affinity Capture-Western; Co-purification; Reconstituted Complex | BioGRID | 10783165 |12034743 |
| ATM | PRKDC | - | HPRD,BioGRID | 10464290 |
| ATM | AP2A2 | Protein-peptide | BioGRID | 10608806 |
| ATM | MSH6 | Co-purification | BioGRID | 10783165 |
| ATM | MLH1 | Co-purification | BioGRID | 10783165 |
| ATM | PTS | Protein-peptide | BioGRID | 10608806 |
| ATM | TIPARP | - | HPRD | 11238919 |
| ATM | XRCC5 | XRCC5 (Ku80) interacts with ATM. | BIND | 15758953 |
| ATM | EIF4EBP1 | Protein-peptide | BioGRID | 10608806 |
| ATM | LIG4 | Protein-peptide | BioGRID | 10608806 |
| ATM | NBN | Co-purification; Protein-peptide | BioGRID | 10608806 |10783165 |
| NBS1 interacts with ATM. | BIND | 15758953 | ||
| ATM | AP1B1 | Protein-peptide | BioGRID | 10608806 |
| ATM | RAD17 | - | HPRD,BioGRID | 11418864 |
| ATM | UPF1 | ATM phosphorylates hUpf1. | BIND | 15175154 |
| ATM | MRE11A | ATM interacts with MRE11A (Mre11). | BIND | 15758953 |
| Co-purification; Protein-peptide | BioGRID | 10608806 |10783165 | ||
| ATM | ABL1 | - | HPRD,BioGRID | 9168117 |
| ATM | EEF1E1 | p18 interacts with ATM. | BIND | 15680327 |
| ATM | RHEB | Affinity Capture-Western; Reconstituted Complex | BioGRID | 15854902 |
| ATM interacts with Rheb. | BIND | 15854902 | ||
| ATM | RFC1 | Co-purification | BioGRID | 10783165 |
| ATM | MRE11A | ATM interacts with MRE11A (Mre11). | BIND | 15758953 |
| Co-purification; Protein-peptide | BioGRID | 10608806 |10783165 | ||
| ATM | CAT | - | HPRD | 10567403 |
| ATM | CREB1 | Affinity Capture-Western | BioGRID | 15073328 |
| ATM | AP3B2 | - | HPRD | 9707615 |
| ATM | E4F1 | Protein-peptide | BioGRID | 10608806 |
| ATM | AP2B1 | - | HPRD | 9707615 |
| ATM | WRN | Protein-peptide | BioGRID | 10608806 |
| ATM | ATF2 | An unspecified isoform of ATM interacts with and phosphorylates ATF2. | BIND | 15916964 |
| ATM | H2AFX | ATM phosphorylates the carboxy terminus of H2AX. | BIND | 15064416 |
| ATM | RBBP8 | Affinity Capture-Western; Protein-peptide; Reconstituted Complex | BioGRID | 10608806 |10910365 |
| ATM | PEX5 | - | HPRD,BioGRID | 10567403 |
| ATM | SMC1A | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11877376 |
| ATM | MCM2 | Biochemical Activity | BioGRID | 15210935 |
| ATM | FANCD2 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 12086603 |14499622 |
| RAD9A | ABL1 | - | HPRD,BioGRID | 11971963 |
| RAD9A | PCNA | - | HPRD | 11994305 |
| RAD9A | ITSN2 | - | HPRD | 12766152 |
| RAD9A | HDAC1 | - | HPRD,BioGRID | 10846170 |
| RAD9A | BCL2L1 | Affinity Capture-Western; Two-hybrid | BioGRID | 10620799 |16189514 |
| RAD9A | NR3C1 | Reconstituted Complex | BioGRID | 14966297 |
| RAD9A | BCL2 | - | HPRD,BioGRID | 10620799 |
| RAD9A | AR | Two-hybrid | BioGRID | 14966297 |
| RAD9A | HUS1B | Affinity Capture-Western | BioGRID | 14611806 |
| RAD9A | HUS1 | Rad9 interacts with Hus1. | BIND | 15897895 |
| - | HPRD,BioGRID | 9872989 | ||
| Rad9 interacts with Hus1. | BIND | 11573955 | ||
| RAD9A | RPA1 | Rad9 interacts with RPA70. | BIND | 15897895 |
| RAD9A | HUS1 | Rad9 interacts with Hus1. | BIND | 15897895 |
| - | HPRD,BioGRID | 9872989 | ||
| Rad9 interacts with Hus1. | BIND | 11573955 | ||
| RAD9A | RAD17 | - | HPRD,BioGRID | 10884395 |
| - | HPRD | 10884395|12578958 | ||
| RAD9A | RAD1 | - | HPRD,BioGRID | 9872989 |
| RAD9A | HUS1 | Rad9 interacts with Hus1. | BIND | 15897895 |
| - | HPRD,BioGRID | 9872989 | ||
| Rad9 interacts with Hus1. | BIND | 11573955 | ||
| RAD9A | DNAJC7 | - | HPRD,BioGRID | 11573955 |
| Tpr2 interacts with Rad9. | BIND | 11573955 | ||
| RAD9A | RPA2 | Rad9 interacts with RPA32. | BIND | 15897895 |
| RAD9A | TOPBP1 | - | HPRD,BioGRID | 11395493 |
| RAD9A | DNAJC7 | - | HPRD,BioGRID | 11573955 |
| Tpr2 interacts with Rad9. | BIND | 11573955 | ||
| RAD9A | RAD17 | - | HPRD,BioGRID | 10884395 |
| - | HPRD | 10884395|12578958 | ||
| RAD9A | CLSPN | - | HPRD,BioGRID | 12766152 |
| BRCA1 | CSTF2 | Affinity Capture-Western; Co-purification | BioGRID | 10477523 |11257228 |
| BRCA1 | JUNB | BRCA1 interacts with JunB. | BIND | 12080089 |
| - | HPRD,BioGRID | 12080089 | ||
| BRCA1 | CSNK2B | Reconstituted Complex; Two-hybrid | BioGRID | 10403822 |
| BRCA1 is phosphorylated by Casein kinase 2 through a physical interaction with CSNK2B | BIND | 10403822 | ||
| BRCA1 | RFC1 | - | HPRD,BioGRID | 10783165 |
| BRCA1 | APLP2 | Far Western | BioGRID | 11746496 |
| BRCA1 | TOP2A | TOP2A (Topo II) interacts with BRCA1 | BIND | 15965487 |
| BRCA1 | BAP1 | - | HPRD | 9528852 |
| BRCA1 | RB1 | - | HPRD,BioGRID | 10220405 |
| BRCA1 interacts with Rb. | BIND | 10518542 | ||
| BRCA1 | UBE2D3 | - | HPRD | 12732733 |
| BRCA1 | PRKDC | Protein-peptide | BioGRID | 10608806 |
| BRCA1 | STAT3 | - | HPRD | 11163768 |
| BRCA1 | BARD1 | Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; Co-purification; FRET; Reconstituted Complex; Two-hybrid | BioGRID | 8944023 |9342365 |9738006 |9788437 |10026184 |10477523 |10635334 |11257228 |11278247 |11301010 |11498787 |11504724 |11526114 |11573085 |11773071 |11925436 |11927591 |12431996 |12438698 |12485996 |12700228 |12732733 |12887909 |12890688 |12951069 |14636569 |14638690 |14647430 |15159397 |15184379 |
| - | HPRD | 8944023 |10026184 |11573085 |11773071 |12431996 | ||
| - | HPRD | 8944023 |10026184 |11773071 |12431996 | ||
| BRCA1 | NUP153 | Protein-peptide | BioGRID | 14578343 |
| BRCA1 | XIST | Co-localization | BioGRID | 12419249 |15065664 |
| BRCA1 | MAP3K3 | Affinity Capture-Western; Two-hybrid | BioGRID | 15205325 |
| BRCA1 interacts with MEKK3. | BIND | 15205325 | ||
| BRCA1 | RBBP7 | BRCA1 interacts with RbAp46. | BIND | 10220405 |
| - | HPRD,BioGRID | 10220405 | ||
| BRCA1 | UBE2L3 | - | HPRD,BioGRID | 12732733 |
| BRCA1 | MSH3 | Protein-peptide; Reconstituted Complex | BioGRID | 11498787 |14578343 |
| BRCA1 | CDS1 | Reconstituted Complex | BioGRID | 12438214 |
| BRCA1 | NCOA3 | Protein-peptide | BioGRID | 14578343 |
| BRCA1 | UBE2D1 | Reconstituted Complex | BioGRID | 11278247 |11927591 |12438698 |12485996 |12732733 |12887909 |12890688 |14636569 |14638690 |15184379 |
| BRCA1 | NPM1 | Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex | BioGRID | 15184379 |
| BRCA1 | NMI | - | HPRD,BioGRID | 11916966 |
| BRCA1 interacts with Nmi. | BIND | 11916966 | ||
| BRCA1 | HDAC2 | - | HPRD,BioGRID | 10220405 |
| BRCA1 interacts with HDAC2 | BIND | 10220405 | ||
| BRCA1 | CCNA1 | BRCA1 associates with Cyclin A | BIND | 9244350 |10373534 |
| Reconstituted Complex | BioGRID | 9244350 | ||
| BRCA1 | CDK8 | Co-purification | BioGRID | 9159119 |
| BRCA1 | CCNA2 | - | HPRD,BioGRID | 9244350 |10373534 |
| BRCA1 | SMARCC2 | Co-purification | BioGRID | 10943845 |
| BRCA1 | CDC2 | - | HPRD,BioGRID | 9244350 |
| BRCA1 | JUN | BRCA1 interacts with c-Jun. | BIND | 12080089 |
| - | HPRD,BioGRID | 12080089 | ||
| BRCA1 | HDAC1 | BRCA1 interacts with HDAC1 | BIND | 10220405 |
| - | HPRD,BioGRID | 10220405 | ||
| BRCA1 | E2F1 | BRCA1 associates with E2F-1 | BIND | 9244350 |
| - | HPRD | 9244350 | ||
| BRCA1 | NCOA2 | Protein-peptide; Reconstituted Complex | BioGRID | 11085509 |14578343 |
| BRCA1 | HIST2H2AC | Reconstituted Complex | BioGRID | 11927591 |
| BRCA1 | HIST2H3C | Co-localization | BioGRID | 12419249 |
| BRCA1 | MED23 | Affinity Capture-MS | BioGRID | 15208681 |
| BRCA1 | E2F4 | BRCA1 associates with E2F-4 | BIND | 9244350 |
| - | HPRD,BioGRID | 9244350 | ||
| BRCA1 | POLR2A | - | HPRD | 4506230 |9159119 |12154023|10725406 |
| - | HPRD | 4506230 |9159119 |12154023 | ||
| Affinity Capture-Western; Co-purification | BioGRID | 9159119 |11504724 |12955082 |14506230 | ||
| BRCA1 | MED17 | Affinity Capture-MS; Co-purification | BioGRID | 11504724 |12154023 |15208681 |
| BRCA1 | PCTK1 | Two-hybrid | BioGRID | 9738006 |
| BRCA1 | NFKB1 | - | HPRD | 12700228 |
| BRCA1 | ATR | BRCA1 physically and functionally interacts with ATR during genotoxic stress | BIND | 11016625 |11278964 |
| Affinity Capture-Western; Protein-peptide; Reconstituted Complex | BioGRID | 10608806 |11016625 |11114888 |11278964 | ||
| BRCA1 | NUFIP1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 15107825 |
| BRCA1 interacts with NUFIP. | BIND | 15107825 | ||
| BRCA1 | CCND1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with Cyclin D1 | BIND | 9244350 | ||
| BRCA1 | HSPA8 | Two-hybrid | BioGRID | 9738006 |
| BRCA1 | MSH6 | BRCA1 associates with MSH6. | BIND | 10783165 |11498787 |
| - | HPRD,BioGRID | 11498787 | ||
| BRCA1 | CREBBP | - | HPRD,BioGRID | 10655477 |
| CBP interacts with BRCA1. This interaction was modelled on a demonstrated interaction between human BRCA1 and mouse CBP. | BIND | 10655477 | ||
| BRCA1 | RBL1 | Co-localization; Reconstituted Complex | BioGRID | 11521194 |
| BRCA1 | ELK1 | - | HPRD | 11313879 |
| BRCA1 | RBL2 | Co-localization; Reconstituted Complex | BioGRID | 11521194 |
| BRCA1 | STAT1 | - | HPRD,BioGRID | 10792030 |
| BRCA1 | BRIP1 | Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Protein-peptide; Reconstituted Complex | BioGRID | 11877378 |14576433 |14578343 |15133502 |15208681 |15242590 |
| - | HPRD | 11301010 | ||
| BRCA1 | SMAD2 | BRCA1 interacts with Smad2. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad2 from an unspecified species. | BIND | 15735739 |
| BRCA1 | CDK4 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with CDK4 | BIND | 9244350 | ||
| BRCA1 | GTF2F1 | Co-purification | BioGRID | 9159119 |
| BRCA1 | GTF2E1 | Co-purification | BioGRID | 9159119 |
| BRCA1 | RAD51 | - | HPRD,BioGRID | 9774970 |
| BRCA1 and Rad51 associate in mitotic and meiotic cells | BIND | 9008167 | ||
| - | HPRD | 9008167 |9774970|9774970 | ||
| BRCA1 | RELA | - | HPRD,BioGRID | 12700228 |
| BRCA1 | TUBG1 | - | HPRD,BioGRID | 9789027 |11691781 |
| BRCA1 | SMARCA2 | Affinity Capture-Western | BioGRID | 15034933 |
| BRCA1 | AURKA | Affinity Capture-Western; Reconstituted Complex | BioGRID | 14990569 |
| BRCA1 | TP53 | BRCA1a interacts with p53. | BIND | 9926942 |
| BRCA1 physically associates with p53 and stimulates its transcriptional activity | BIND | 9582019 | ||
| - | HPRD,BioGRID | 9482880 | ||
| BRCA1 | MAP4K4 | Protein-peptide | BioGRID | 14578343 |
| BRCA1 | BLM | Co-purification | BioGRID | 10783165 |
| BRCA1 | KPNA2 | Two-hybrid | BioGRID | 8955125 |
| - | HPRD | 9497340 | ||
| BRCA1 | CSNK2A1 | - | HPRD,BioGRID | 10403822 |
| BRCA1 | CDK4 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with CDK4 | BIND | 9244350 | ||
| BRCA1 | MYC | - | HPRD,BioGRID | 9788437 |
| BRCA1 association with c-Myc, a proto-oncogene that is implicated in tumorigenesis, embryonic development and apoptosis, inhibits its transcriptional and transforming activity in cells. | BIND | 9788437 | ||
| BRCA1 | CSTF1 | Reconstituted Complex | BioGRID | 11257228 |
| BRCA1 | AR | - | HPRD,BioGRID | 11016951 |11085509 |
| BRCA1 | BARD1 | Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; Co-purification; FRET; Reconstituted Complex; Two-hybrid | BioGRID | 8944023 |9342365 |9738006 |9788437 |10026184 |10477523 |10635334 |11257228 |11278247 |11301010 |11498787 |11504724 |11526114 |11573085 |11773071 |11925436 |11927591 |12431996 |12438698 |12485996 |12700228 |12732733 |12887909 |12890688 |12951069 |14636569 |14638690 |14647430 |15159397 |15184379 |
| - | HPRD | 8944023 |10026184 |11573085 |11773071 |12431996 | ||
| - | HPRD | 8944023 |10026184 |11773071 |12431996 | ||
| BRCA1 | MLH1 | - | HPRD,BioGRID | 10783165 |
| BRCA1 | MED24 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 15208681 |
| BRCA1 | BRAP | - | HPRD,BioGRID | 9497340 |
| BRCA1 | SP1 | - | HPRD | 10720440 |
| BRCA1 interacts with Sp1. | BIND | 12706836 | ||
| Affinity Capture-Western | BioGRID | 12706836 | ||
| BRCA1 | NMI | - | HPRD,BioGRID | 11916966 |
| BRCA1 interacts with Nmi. | BIND | 11916966 | ||
| BRCA1 | FANCA | BRCA1 interacts with FANCA. | BIND | 12354784 |
| - | HPRD,BioGRID | 12354784 | ||
| BRCA1 | ATF1 | - | HPRD,BioGRID | 10945975 |
| BRCA1 | TP53 | BRCA1a interacts with p53. | BIND | 9926942 |
| BRCA1 physically associates with p53 and stimulates its transcriptional activity | BIND | 9582019 | ||
| - | HPRD,BioGRID | 9482880 | ||
| BRCA1 | CDK2 | BRCA1 associates with CDK2 | BIND | 9244350 |10373534 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8764100 |9244350 |10373534 | ||
| BRCA1 | COBRA1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 11739404 |
| - | HPRD | 12612062 | ||
| BRCA1 | LMO4 | - | HPRD,BioGRID | 11751867 |
| The LIM domain protein LMO4 interacts with BRCA1 | BIND | 11751867 | ||
| BRCA1 | NFYA | - | HPRD,BioGRID | 11777930 |
| BRCA1 interacts with NF-YA | BIND | 11777930 | ||
| BRCA1 | MED1 | BRCA1 interacts with TRAP220. | BIND | 15208681 |
| Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex | BioGRID | 15208681 | ||
| BRCA1 | E2F1 | BRCA1 associates with E2F-1 | BIND | 9244350 |
| - | HPRD | 9244350 | ||
| BRCA1 | PEG3 | Far Western | BioGRID | 11746496 |
| BRCA1 | BRCC3 | Affinity Capture-MS; Affinity Capture-Western; Co-purification | BioGRID | 14636569 |
| BRCA1 | RBBP8 | - | HPRD | 9738006 |10196224 |
| Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid | BioGRID | 9738006 |9811458 |10196224 |10764811 |10910365 |11689934 |14578343 | ||
| BRCA1 interacts with CtIP. | BIND | 9811458 | ||
| BRCA1 | POLR2A | - | HPRD | 4506230 |9159119 |12154023|10725406 |
| - | HPRD | 4506230 |9159119 |12154023 | ||
| Affinity Capture-Western; Co-purification | BioGRID | 9159119 |11504724 |12955082 |14506230 | ||
| BRCA1 | TP53 | BRCA1a interacts with p53. | BIND | 9926942 |
| BRCA1 physically associates with p53 and stimulates its transcriptional activity | BIND | 9582019 | ||
| - | HPRD,BioGRID | 9482880 | ||
| BRCA1 | JUND | - | HPRD,BioGRID | 12080089 |
| BRCA1 interacts with JunD. | BIND | 12080089 | ||
| BRCA1 | ZNF350 | - | HPRD,BioGRID | 11090615 |
| BRCA1 | RBBP8 | - | HPRD | 9738006 |10196224 |
| Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid | BioGRID | 9738006 |9811458 |10196224 |10764811 |10910365 |11689934 |14578343 | ||
| BRCA1 interacts with CtIP. | BIND | 9811458 | ||
| BRCA1 | POLR2K | - | HPRD | 10725406 |
| BRCA1 | CREBBP | - | HPRD,BioGRID | 10655477 |
| CBP interacts with BRCA1. This interaction was modelled on a demonstrated interaction between human BRCA1 and mouse CBP. | BIND | 10655477 | ||
| BRCA1 | FLNA | - | HPRD | 11602572 |
| BRCA1 | ESR1 | - | HPRD | 10334989 |
| Affinity Capture-Western; Co-localization; Reconstituted Complex | BioGRID | 11244506 |11493692 |11782371 |12400015 | ||
| BRCA1 | HDAC1 | BRCA1 interacts with HDAC1 | BIND | 10220405 |
| - | HPRD,BioGRID | 10220405 | ||
| BRCA1 | UBB | BRCA1 interacts with Ub. This interaction was modelled on a demonstrated interaction between human BRCA1 and Ub from an unspecified source. | BIND | 11320250 |
| BRCA1 | CCNB1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 is a tyrosine phosphoprotein that associates with Cyclin B1 | BIND | 9244350 | ||
| BRCA1 | DHX9 | - | HPRD | 9662397|12592385 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 9662397 |12592385 | ||
| BRCA1 | RPL31 | Far Western; Reconstituted Complex | BioGRID | 11746496 |
| BRCA1 | EP300 | - | HPRD,BioGRID | 10655477 |
| p300 interacts with BRCA1. | BIND | 10655477 | ||
| BRCA1 | MSH6 | BRCA1 associates with MSH6. | BIND | 10783165 |11498787 |
| - | HPRD,BioGRID | 11498787 | ||
| BRCA1 | COBRA1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 11739404 |
| - | HPRD | 12612062 | ||
| BRCA1 | KPNA2 | Two-hybrid | BioGRID | 8955125 |
| - | HPRD | 9497340 | ||
| BRCA1 | JUND | - | HPRD,BioGRID | 12080089 |
| BRCA1 interacts with JunD. | BIND | 12080089 | ||
| BRCA1 | EP300 | - | HPRD,BioGRID | 10655477 |
| p300 interacts with BRCA1. | BIND | 10655477 | ||
| BRCA1 | SMARCC1 | Co-purification | BioGRID | 10943845 |
| BRCA1 | JAK1 | - | HPRD,BioGRID | 11163768 |
| BRCA1 | SMARCD2 | Co-purification | BioGRID | 10943845 |
| BRCA1 | FANCD2 | Co-localization; Reconstituted Complex; Two-hybrid | BioGRID | 12887909 |14499622 |
| - | HPRD | 11239454 | ||
| BRCA1 | SMAD3 | BRCA1 interacts with Smad3. | BIND | 15735739 |
| BRCA1 | WNT2B | Far Western | BioGRID | 11746496 |
| BRCA1 | BRE | Affinity Capture-MS; Affinity Capture-Western; Co-purification | BioGRID | 14636569 |
| BRCA1 | MED21 | - | HPRD,BioGRID | 9159119 |
| BRCA1 | ETS1 | Reconstituted Complex | BioGRID | 11313879 |
| BRCA1 | E2F4 | BRCA1 associates with E2F-4 | BIND | 9244350 |
| - | HPRD,BioGRID | 9244350 | ||
| BRCA1 | MED13 | Affinity Capture-MS | BioGRID | 15208681 |
| BRCA1 | ELK4 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 11313879 |
| BRCA1 | SP1 | - | HPRD | 10720440 |
| BRCA1 interacts with Sp1. | BIND | 12706836 | ||
| Affinity Capture-Western | BioGRID | 12706836 | ||
| BRCA1 | CCNE1 | Affinity Capture-Western | BioGRID | 17525332 |
| BRCA1 | PPP1CA | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12438214 |
| BRCA1 | ACACA | - | HPRD,BioGRID | 12360400 |
| BRCA1 interacts with acetyl-CoA carboxylase. | BIND | 12360400 | ||
| BRCA1 | ABL1 | Affinity Capture-Western | BioGRID | 12024016 |
| BRCA1 | NFYA | - | HPRD,BioGRID | 11777930 |
| BRCA1 interacts with NF-YA | BIND | 11777930 | ||
| BRCA1 | ORC3L | Affinity Capture-Western | BioGRID | 17525332 |
| BRCA1 | CCNB1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 is a tyrosine phosphoprotein that associates with Cyclin B1 | BIND | 9244350 | ||
| BRCA1 | BRIP1 | Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Protein-peptide; Reconstituted Complex | BioGRID | 11877378 |14576433 |14578343 |15133502 |15208681 |15242590 |
| - | HPRD | 11301010 | ||
| BRCA1 | FANCD2 | Co-localization; Reconstituted Complex; Two-hybrid | BioGRID | 12887909 |14499622 |
| - | HPRD | 11239454 | ||
| BRCA1 | H2AFX | Co-localization; Reconstituted Complex | BioGRID | 10959836 |11927591 |12485996 |
| BRCA1 | LMO4 | - | HPRD,BioGRID | 11751867 |
| The LIM domain protein LMO4 interacts with BRCA1 | BIND | 11751867 | ||
| BRCA1 | CDK5 | Reconstituted Complex | BioGRID | 9244350 |
| BRCA1 | KIF1B | Protein-peptide | BioGRID | 14578343 |
| BRCA1 | JAK2 | - | HPRD,BioGRID | 11163768 |
| BRCA1 | DHX9 | - | HPRD | 9662397|12592385 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 9662397 |12592385 | ||
| BRCA1 | CTBP1 | - | HPRD,BioGRID | 10196224 |
| BRCA1 | USF2 | - | HPRD,BioGRID | 14502648 |
| BRCA1 | CTCFL | Protein-peptide | BioGRID | 14578343 |
| BRCA1 | CCND1 | - | HPRD,BioGRID | 9244350 |
| BRCA1 associates with Cyclin D1 | BIND | 9244350 | ||
| BRCA1 | RB1 | - | HPRD,BioGRID | 10220405 |
| BRCA1 interacts with Rb. | BIND | 10518542 | ||
| BRCA1 | UBE3A | Reconstituted Complex | BioGRID | 12890688 |
| BRCA1 | MAP3K3 | Affinity Capture-Western; Two-hybrid | BioGRID | 15205325 |
| BRCA1 interacts with MEKK3. | BIND | 15205325 | ||
| BRCA1 | DNAJA3 | Protein-peptide | BioGRID | 14578343 |
| BRCA1 | CSNK2B | Reconstituted Complex; Two-hybrid | BioGRID | 10403822 |
| BRCA1 is phosphorylated by Casein kinase 2 through a physical interaction with CSNK2B | BIND | 10403822 | ||
| BRCA1 | BACH1 | - | HPRD,BioGRID | 11301010 |
| BRCA1 | ZCCHC8 | Affinity Capture-Western | BioGRID | 17525332 |
| BRCA1 | AKT1 | Reconstituted Complex | BioGRID | 10542266 |
| BRCA1 | POU2F1 | Affinity Capture-Western | BioGRID | 11777930 |
| BRCA1 interacts with Oct-1. | BIND | 11777930 | ||
| BRCA1 | H2AFY | Co-localization | BioGRID | 12419249 |
| BRCA1 | BARD1 | Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; Co-purification; FRET; Reconstituted Complex; Two-hybrid | BioGRID | 8944023 |9342365 |9738006 |9788437 |10026184 |10477523 |10635334 |11257228 |11278247 |11301010 |11498787 |11504724 |11526114 |11573085 |11773071 |11925436 |11927591 |12431996 |12438698 |12485996 |12700228 |12732733 |12887909 |12890688 |12951069 |14636569 |14638690 |14647430 |15159397 |15184379 |
| - | HPRD | 8944023 |10026184 |11573085 |11773071 |12431996 | ||
| - | HPRD | 8944023 |10026184 |11773071 |12431996 | ||
| BRCA1 | RBBP4 | BRCA1 interacts with RbAp48. | BIND | 10220405 |
| - | HPRD,BioGRID | 10220405 | ||
| BRCA1 | STAT5A | - | HPRD,BioGRID | 12459499 |
| BRCA1 | ATR | BRCA1 physically and functionally interacts with ATR during genotoxic stress | BIND | 11016625 |11278964 |
| Affinity Capture-Western; Protein-peptide; Reconstituted Complex | BioGRID | 10608806 |11016625 |11114888 |11278964 | ||
| BRCA1 | RBBP8 | - | HPRD | 9738006 |10196224 |
| Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid | BioGRID | 9738006 |9811458 |10196224 |10764811 |10910365 |11689934 |14578343 | ||
| BRCA1 interacts with CtIP. | BIND | 9811458 | ||
| BRCA1 | MED1 | BRCA1 interacts with TRAP220. | BIND | 15208681 |
| Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex | BioGRID | 15208681 | ||
| BRCA1 | CLSPN | - | HPRD,BioGRID | 15096610 |
| BRCA1 | RBBP4 | BRCA1 interacts with RbAp48. | BIND | 10220405 |
| - | HPRD,BioGRID | 10220405 | ||
| BRCA1 | FANCA | BRCA1 interacts with FANCA. | BIND | 12354784 |
| - | HPRD,BioGRID | 12354784 | ||
| BRCA1 | RAD51 | - | HPRD,BioGRID | 9774970 |
| BRCA1 and Rad51 associate in mitotic and meiotic cells | BIND | 9008167 | ||
| - | HPRD | 9008167 |9774970|9774970 | ||
| BRCA1 | UBA1 | Reconstituted Complex | BioGRID | 11278247 |11927591 |12438698 |12485996 |12887909 |14638690 |15184379 |
| BRCA1 | ACACA | - | HPRD,BioGRID | 12360400 |
| BRCA1 interacts with acetyl-CoA carboxylase. | BIND | 12360400 | ||
| BRCA1 | NUFIP1 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 15107825 |
| BRCA1 interacts with NUFIP. | BIND | 15107825 | ||
| BRCA1 | SMAD4 | BRCA1 interacts with Smad4. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad4 from an unspecified species. | BIND | 15735739 |
| BRCA1 | HDAC2 | - | HPRD,BioGRID | 10220405 |
| BRCA1 interacts with HDAC2 | BIND | 10220405 | ||
| BRCA1 | SMARCB1 | Co-purification | BioGRID | 10943845 |
| BRCA1 | GTF2H4 | Co-purification | BioGRID | 9159119 |
| BRCA1 | JUNB | BRCA1 interacts with JunB. | BIND | 12080089 |
| - | HPRD,BioGRID | 12080089 | ||
| BRCA1 | FLI1 | Reconstituted Complex | BioGRID | 11313879 |
| BRCA1 | RAD51 | - | HPRD,BioGRID | 9774970 |
| BRCA1 and Rad51 associate in mitotic and meiotic cells | BIND | 9008167 | ||
| - | HPRD | 9008167 |9774970|9774970 | ||
| BRCA1 | SMARCA4 | - | HPRD,BioGRID | 10943845 |
| BRCA1 | NBN | - | HPRD,BioGRID | 10426999 |10783165 |
| BRCA1 | ETS2 | ETS2 (Ets-2) interacts with BRCA1 promoter. This interaction was modeled on a demonstrated interaction between ETS2 from an unspecified species and BRCA1 promoter from an unspecified species. | BIND | 12637547 |
| BRCA1 | MRE11A | Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex | BioGRID | 10426999 |10783165 |11353843 |11504724 |
| BRCA1 | ESR1 | - | HPRD | 10334989 |
| Affinity Capture-Western; Co-localization; Reconstituted Complex | BioGRID | 11244506 |11493692 |11782371 |12400015 | ||
| BRCA1 | MYC | - | HPRD,BioGRID | 9788437 |
| BRCA1 association with c-Myc, a proto-oncogene that is implicated in tumorigenesis, embryonic development and apoptosis, inhibits its transcriptional and transforming activity in cells. | BIND | 9788437 | ||
| BRCA1 | JUN | BRCA1 interacts with c-Jun. | BIND | 12080089 |
| - | HPRD,BioGRID | 12080089 | ||
| BRCA1 | CCNA1 | BRCA1 associates with Cyclin A | BIND | 9244350 |10373534 |
| Reconstituted Complex | BioGRID | 9244350 | ||
| BRCA1 | CDK2 | BRCA1 associates with CDK2 | BIND | 9244350 |10373534 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 8764100 |9244350 |10373534 | ||
| BRCA1 | POU2F1 | Affinity Capture-Western | BioGRID | 11777930 |
| BRCA1 interacts with Oct-1. | BIND | 11777930 | ||
| BRCA1 | XRCC1 | - | HPRD | 11352725 |
| BRCA1 | SMC1A | - | HPRD | 11877377 |
| BRCA1 | POLR2A | - | HPRD | 4506230 |9159119 |12154023|10725406 |
| - | HPRD | 4506230 |9159119 |12154023 | ||
| Affinity Capture-Western; Co-purification | BioGRID | 9159119 |11504724 |12955082 |14506230 | ||
| BRCA1 | SP1 | - | HPRD | 10720440 |
| BRCA1 interacts with Sp1. | BIND | 12706836 | ||
| Affinity Capture-Western | BioGRID | 12706836 | ||
| BRCA1 | FHL2 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 14550570 |14986435 |
| BRCA1 | CREB1 | Phenotypic Enhancement | BioGRID | 10945975 |
| BRCA1 | ORC2L | Affinity Capture-Western | BioGRID | 17525332 |
| BRCA1 | RBBP7 | BRCA1 interacts with RbAp46. | BIND | 10220405 |
| - | HPRD,BioGRID | 10220405 | ||
| PLK1 | PIN1 | - | HPRD,BioGRID | 9499405 |
| Pin1 interacts with PLK1. | BIND | 9499405 | ||
| PLK1 | DCTN1 | Affinity Capture-Western | BioGRID | 12852857 |
| PLK1 | PSMA1 | Affinity Capture-Western | BioGRID | 11205743 |
| PLK1 | PSMA5 | - | HPRD,BioGRID | 11205743 |
| PLK1 | MAGED1 | Two-hybrid | BioGRID | 16169070 |
| PLK1 | PITPNM1 | Nir2 interacts with Plk1. | BIND | 15125835 |
| PLK1 | TSC2 | Affinity Capture-Western | BioGRID | 16339216 |
| PLK1 | RECQL5 | Two-hybrid | BioGRID | 16169070 |
| PLK1 | PSMA3 | - | HPRD,BioGRID | 11205743 |
| PLK1 | PSMB6 | Affinity Capture-Western | BioGRID | 11205743 |
| PLK1 | PSMB7 | Affinity Capture-Western | BioGRID | 11205743 |
| PLK1 | PIN1 | - | HPRD,BioGRID | 9499405 |
| Pin1 interacts with PLK1. | BIND | 9499405 | ||
| PLK1 | ASPM | - | HPRD | 11283617 |
| PLK1 | GORASP1 | - | HPRD | 11447294 |
| PLK1 | PSMB1 | - | HPRD,BioGRID | 11205743 |
| PLK1 | PSMA4 | - | HPRD,BioGRID | 11205743 |
| PLK1 | PSMB3 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 11205743 |
| PLK1 | KIF23 | - | HPRD | 8524282 |
| PLK1 | CDC25C | - | HPRD,BioGRID | 11202906 |
| Plk1 phosphorylates an unspecified isoform of CDC25C. This interaction was modeled on a demonstrated phosphorylation of CDC25C from an unspecified species by human Plk1. | BIND | 15766665 | ||
| PLK1 | WEE1 | Wee1A interacts with and is phophorylated by Plk1. This interaction was modeled on a demonstrated interaction between human Wee1A and mouse Plk1. | BIND | 15070733 |
| PLK1 | PSMA7 | - | HPRD,BioGRID | 11205743 |
| PLK1 | PSMB5 | Affinity Capture-Western | BioGRID | 11205743 |
| PLK1 | NUDC | - | HPRD,BioGRID | 12852857 |
| PLK1 | PSMA2 | Affinity Capture-MS | BioGRID | 11205743 |
| PLK1 | TSC1 | Affinity Capture-Western | BioGRID | 16339216 |
| PLK1 | NPM1 | - | HPRD | 15190079 |
| PLK1 | PSMA6 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 11205743 |
| PLK1 | C7orf20 | Two-hybrid | BioGRID | 16169070 |
| PLK1 | CDC25C | - | HPRD,BioGRID | 11202906 |
| Plk1 phosphorylates an unspecified isoform of CDC25C. This interaction was modeled on a demonstrated phosphorylation of CDC25C from an unspecified species by human Plk1. | BIND | 15766665 | ||
| PLK1 | DNAJB9 | Two-hybrid | BioGRID | 16169070 |
| TP53BP1 | H2AFX | - | HPRD,BioGRID | 12697768 |
| TP53BP1 | DCLRE1C | Artemis interacts with 53BP1. | BIND | 15574327 |
| TP53BP1 | E2F1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 8896460 |
| TP53BP1 | TP53 | Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybrid | BioGRID | 8016121 |11877378 |12110597 |12351827 |14978302 |15364958 |15611139 |
| - | HPRD | 8016121 |12110597 | ||
| TP53BP1 | CHEK1 | Co-localization | BioGRID | 15364958 |
| TP53BP1 | TP53 | Affinity Capture-Western; Co-crystal Structure; Co-localization; Reconstituted Complex; Two-hybrid | BioGRID | 8016121 |11877378 |12110597 |12351827 |14978302 |15364958 |15611139 |
| - | HPRD | 8016121 |12110597 | ||
| TP53BP1 | DCTN1 | Affinity Capture-Western | BioGRID | 15611139 |
| TP53BP1 | NFKB1 | Affinity Capture-Western | BioGRID | 10646849 |
| TP53BP1 | DYNLL1 | Affinity Capture-Western; Protein-peptide; Two-hybrid | BioGRID | 15611139 |
| TP53BP1 | PAXIP1 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 14576432 |15456759 |
| TP53BP1 | TFDP1 | Reconstituted Complex | BioGRID | 8896460 |
| TP53BP1 | RPA2 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 15856006 |
| TP53BP1 | BLM | Affinity Capture-Western; Co-localization | BioGRID | 15364958 |
| TP53BP1 | RPA1 | Affinity Capture-MS; Affinity Capture-Western | BioGRID | 15856006 |
| TP53BP1 | NEK1 | NEK1 interacts with 53BP1. | BIND | 14690447 |
| TP53BP1 | DCLRE1A | Affinity Capture-Western | BioGRID | 12446782 |
| MSH2 | MSH6 | MSH2 interacts with MSH6. | BIND | 15753043 |
| MSH2 interacts with MSH6. | BIND | 9428522 | ||
| - | HPRD,BioGRID | 8942985 |9774676 | ||
| MSH2 | MAX | - | HPRD,BioGRID | 12584560 |
| Max interacts with MSH2. This is a modeled interaction between Max from an unspecified source and human MSH2. | BIND | 12584560 | ||
| MSH2 | E2F1 | E2F1 interacts with the MSH2 promoter. | BIND | 11799067 |
| The 5'MSH2 promoter region interacts with E2F1. | BIND | 15619620 | ||
| MSH2 | PCNA | - | HPRD,BioGRID | 8858149 |12171929 |
| MSH2 | E2F3 | E2F3 interacts with the MSH2 promoter. | BIND | 11799067 |
| MSH2 | MSH6 | MSH2 interacts with MSH6. | BIND | 15753043 |
| MSH2 interacts with MSH6. | BIND | 9428522 | ||
| - | HPRD,BioGRID | 8942985 |9774676 | ||
| MSH2 | E2F4 | E2F4 interacts with the MSH2 promoter. | BIND | 11799067 |
| MSH2 | MYC | Affinity Capture-Western | BioGRID | 12584560 |
| MSH2 | CHEK1 | Affinity Capture-Western | BioGRID | 15647386 |
| MSH2 | BLM | Co-purification | BioGRID | 10783165 |
| MSH2 | MSH6 | MSH2 interacts with MSH6. | BIND | 15753043 |
| MSH2 interacts with MSH6. | BIND | 9428522 | ||
| - | HPRD,BioGRID | 8942985 |9774676 | ||
| MSH2 | MAX | - | HPRD,BioGRID | 12584560 |
| Max interacts with MSH2. This is a modeled interaction between Max from an unspecified source and human MSH2. | BIND | 12584560 | ||
| MSH2 | SMC1A | - | HPRD | 14657349 |
| MSH2 | MLH1 | Co-purification | BioGRID | 10783165 |
| MSH2 | BARD1 | - | HPRD,BioGRID | 11498787 |
| MSH2 | EXO1 | The exonuclease hEXO1b interacts with the mismatch repair protein hMSH2. | BIND | 11429708 |
| The exonuclease HEX1 interacts with the mismatch repair protein hMSH2. | BIND | 11429708 | ||
| - | HPRD,BioGRID | 9788596 |10856833 | ||
| MSH2 | MRE11A | Co-purification | BioGRID | 10783165 |
| MSH2 | ATR | - | HPRD,BioGRID | 14657349 |
| MSH2 | EXO1 | The exonuclease hEXO1b interacts with the mismatch repair protein hMSH2. | BIND | 11429708 |
| The exonuclease HEX1 interacts with the mismatch repair protein hMSH2. | BIND | 11429708 | ||
| - | HPRD,BioGRID | 9788596 |10856833 | ||
| MSH2 | MSH3 | MSH2/HNPCC interacts with MSH3 | BIND | 9774676 |
| - | HPRD,BioGRID | 8942985 |9774676 | ||
| MSH2 | EXO1 | The exonuclease hEXO1b interacts with the mismatch repair protein hMSH2. | BIND | 11429708 |
| The exonuclease HEX1 interacts with the mismatch repair protein hMSH2. | BIND | 11429708 | ||
| - | HPRD,BioGRID | 9788596 |10856833 | ||
| MSH2 | MSH3 | MSH2/HNPCC interacts with MSH3 | BIND | 9774676 |
| - | HPRD,BioGRID | 8942985 |9774676 | ||
| MSH2 | E2F1 | E2F1 interacts with the MSH2 promoter. | BIND | 11799067 |
| The 5'MSH2 promoter region interacts with E2F1. | BIND | 15619620 | ||
| MSH2 | RFC1 | Co-purification | BioGRID | 10783165 |
| MSH2 | NBN | Co-purification | BioGRID | 10783165 |
| MSH2 | PTP4A3 | Affinity Capture-MS | BioGRID | 17353931 |
| MSH2 | ATRIP | Affinity Capture-Western | BioGRID | 14657349 |
| VCP | STX5 | - | HPRD | 9506515 |
| VCP | NSFL1C | - | HPRD,BioGRID | 12529442 |12810701|12810701 |
| - | HPRD | 12810701 | ||
| VCP | HLA-B | Affinity Capture-MS | BioGRID | 17353931 |
| VCP | NSFL1C | - | HPRD,BioGRID | 12529442 |12810701|12810701 |
| - | HPRD | 12810701 | ||
| VCP | ATXN3 | - | HPRD,BioGRID | 12944474 |
| VCP | SGK1 | Affinity Capture-MS | BioGRID | 17353931 |
| VCP | NFKBIA | - | HPRD,BioGRID | 9452483 |
| VCP | TRAF6 | Affinity Capture-MS | BioGRID | 17353931 |
| VCP | MCC | Affinity Capture-MS | BioGRID | 17353931 |
| VCP | IKBKE | Affinity Capture-MS | BioGRID | 17353931 |
| VCP | JAK2 | - | HPRD,BioGRID | 11087817 |
| VCP | PSMC1 | - | HPRD,BioGRID | 9452483 |
| VCP | TOMM34 | - | HPRD,BioGRID | 11913976 |
| VCP | AMFR | - | HPRD,BioGRID | 15331598 |
| VCP | DERL1 | - | HPRD | 15215856 |
| VCP | UBE4B | - | HPRD | 12504083 |
| VCP | PPM1B | Affinity Capture-MS | BioGRID | 17353931 |
| VCP | SELS | VIMP interacts with p97. | BIND | 15215856 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 15215856 | ||
| VCP | SELS | VIMP interacts with p97. | BIND | 15215856 |
| Affinity Capture-Western; Reconstituted Complex | BioGRID | 15215856 | ||
| VCP | VCPIP1 | - | HPRD | 12473691 |
| VCP | HDAC6 | - | HPRD | 11689694 |
| VCP | WDR8 | Affinity Capture-MS | BioGRID | 17353931 |
| ATMIN | ATR | ATR interacts with ASCIZ. This interaction was modeled on a demonstrated interaction between yeast ATR and human ASCIZ. | BIND | 15933716 |
| GINS2 | GINS4 | Two-hybrid | BioGRID | 16189514 |
| PLK3 | CDC25C | - | HPRD,BioGRID | 10557092|11551930 |
| PLK3 | CIB1 | - | HPRD,BioGRID | 10523297 |11039900 |
| PLK3 | PTPRC | Affinity Capture-Western | BioGRID | 11551930 |
| PLK3 | TP53 | - | HPRD,BioGRID | 11551930 |
| PLK3 | TRIP13 | Two-hybrid | BioGRID | 16189514 |
| ERCC6 | GTF2E2 | - | HPRD | 8999876 |
| ERCC6 | TP53 | - | HPRD,BioGRID | 10882116 |
| ERCC6 | XAB2 | - | HPRD,BioGRID | 10944529 |
| ERCC6 | ERCC5 | - | HPRD | 8652557 |
| ERCC6 | XPA | - | HPRD,BioGRID | 8999876 |
| Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009. |