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Protein-protein interaction for BTLA
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene BTLA
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| BTLA | VTCN1 | - | HPRD | 12796776 |
| BTLA | PTPN11 | - | HPRD,BioGRID | 12796776 |
| BTLA | PTPN6 | - | HPRD | 12796776 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| PTPN11 | ERBB4 | Affinity Capture-MS | BioGRID | 16729043 |
| PTPN11 | PILRA | - | HPRD | 10660620 |
| Affinity Capture-Western | BioGRID | 10903717 | ||
| PTPN11 | GAB1 | SHP2 interacts with and dephosphorylates Gab1. | BIND | 12582165 |
| - | HPRD,BioGRID | 11940581 | ||
| PTPN11 | INSR | - | HPRD,BioGRID | 7493946 |8135823 |
| PTPN11 | GAB2 | - | HPRD | 10068651 |11287610 |
| Affinity Capture-Western; Two-hybrid | BioGRID | 10391903 |11334882 |11782427 |12135708 | ||
| PTPN11 | LAIR1 | - | HPRD,BioGRID | 9285412 |
| PTPN11 | PECAM1 | Affinity Capture-Western; Far Western; Reconstituted Complex | BioGRID | 9054388 |9774457 |10350061 |10801826 |
| PTPN11 | SIGLEC12 | - | HPRD | 11328818 |
| PTPN11 | TNFRSF1A | - | HPRD | 11786908 |
| PTPN11 | SOS1 | Affinity Capture-Western | BioGRID | 9344843 |9632781 |
| PTPN11 | CAT | Cat interacts with Shp-2. | BIND | 15556604 |
| PTPN11 | JAK1 | - | HPRD,BioGRID | 8995399 |11036942 |12403768 |
| PTPN11 | INPP5D | Affinity Capture-Western | BioGRID | 9110989 |
| PTPN11 | SLAMF6 | - | HPRD,BioGRID | 11489943 |
| PTPN11 | IGF1R | - | HPRD,BioGRID | 7642582 |
| PTPN11 | TEK | - | HPRD | 10521483 |
| PTPN11 | CAV1 | - | HPRD,BioGRID | 12176037 |
| caveolin-1 interacts with SH-PTP2. | BIND | 12176037 | ||
| PTPN11 | EPOR | - | HPRD,BioGRID | 8639815 |
| PTPN11 | CD84 | Affinity Capture-Western | BioGRID | 11689425 |
| PTPN11 | PLCG2 | Affinity Capture-Western | BioGRID | 12135708 |
| PTPN11 | JAK2 | Biochemical Activity; in vivo; Reconstituted Complex | BioGRID | 8639815 |8912646 |8995399 |
| - | HPRD | 7559603 |8912646 |8995399 | ||
| PTPN11 | GAB2 | - | HPRD | 10068651 |11287610 |
| Affinity Capture-Western; Two-hybrid | BioGRID | 10391903 |11334882 |11782427 |12135708 | ||
| PTPN11 | STAT3 | - | HPRD,BioGRID | 11594781 |
| PTPN11 | PXN | - | HPRD | 8986614 |10082579 |10655584 |
| PTPN11 | IRS4 | - | HPRD | 12774026 |
| PTPN11 | MET | - | HPRD | 8662733 |
| PTPN11 | CD33 | - | HPRD,BioGRID | 10206955 |
| PTPN11 | SYNCRIP | Two-hybrid | BioGRID | 9847309 |
| PTPN11 | FRS2 | - | HPRD | 9632781 |11447289 |
| - | HPRD,BioGRID | 9632781 | ||
| PTPN11 | PTK2 | - | HPRD,BioGRID | 7589239 |8986614 |10082579 |10655584 |
| PTPN11 | PDGFRB | Reconstituted Complex; Two-hybrid | BioGRID | 7691811 |11266449 |
| PDGFR interacts with Syp. | BIND | 7688466 | ||
| Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species. | BIND | 8890167 | ||
| PTPN11 | TREML1 | - | HPRD,BioGRID | 15128762 |
| PTPN11 | LCK | - | HPRD | 10617656 |
| PTPN11 | KIT | - | HPRD,BioGRID | 7523381 |9528781 |
| Syp interacts with c-Kit via its SH2 domain. | BIND | 7523381 | ||
| PTPN11 | LY9 | Affinity Capture-Western | BioGRID | 11689425 |
| PTPN11 | SELE | - | HPRD,BioGRID | 11602579 |
| PTPN11 | STAT5A | - | HPRD,BioGRID | 12060651 |
| PTPN11 | JAK2 | Biochemical Activity; in vivo; Reconstituted Complex | BioGRID | 8639815 |8912646 |8995399 |
| - | HPRD | 7559603 |8912646 |8995399 | ||
| PTPN11 | MPZL1 | - | HPRD,BioGRID | 9792637 |
| PTPN11 | PDGFRB | Reconstituted Complex; Two-hybrid | BioGRID | 7691811 |11266449 |
| PDGFR interacts with Syp. | BIND | 7688466 | ||
| Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species. | BIND | 8890167 | ||
| PTPN11 | IRS2 | - | HPRD,BioGRID | 8910607 |
| PTPN11 | LIFR | - | HPRD,BioGRID | 10800945 |
| PTPN11 | PDGFRB | Reconstituted Complex; Two-hybrid | BioGRID | 7691811 |11266449 |
| PDGFR interacts with Syp. | BIND | 7688466 | ||
| Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species. | BIND | 8890167 | ||
| PTPN11 | SLAMF1 | - | HPRD,BioGRID | 11806999 |
| CD150 interacts with SHP-2. This interaction was modelled on a demonstrated interaction between human CD150 and monkey SHP-2. | BIND | 11477068 | ||
| PTPN11 | ERBB2 | Affinity Capture-MS | BioGRID | 16729043 |
| PTPN11 | IL4R | - | HPRD,BioGRID | 11714803 |
| PTPN11 | SIT1 | - | HPRD,BioGRID | 10209036 |11433379 |11491537 |
| PTPN11 | IL6ST | - | HPRD,BioGRID | 10946280 |
| - | HPRD | 9195977 | ||
| PTPN11 | GAB1 | SHP2 interacts with and dephosphorylates Gab1. | BIND | 12582165 |
| - | HPRD,BioGRID | 11940581 | ||
| PTPN11 | FYN | - | HPRD,BioGRID | 10212213 |
| PTPN11 | GRB2 | Affinity Capture-Western; Far Western; Reconstituted Complex | BioGRID | 8041791 |8702859 |8995399 |9362449 |9632781 |9824671 |10080542 |10212213 |10747947 |
| - | HPRD | 8041791 |8702859 |12531430 | ||
| Grb2 interacts with Syp via Syp SH2 domains. | BIND | 7523381 |8195176 | ||
| PTPN11 | GRB2 | Affinity Capture-Western; Far Western; Reconstituted Complex | BioGRID | 8041791 |8702859 |8995399 |9362449 |9632781 |9824671 |10080542 |10212213 |10747947 |
| - | HPRD | 8041791 |8702859 |12531430 | ||
| Grb2 interacts with Syp via Syp SH2 domains. | BIND | 7523381 |8195176 | ||
| PTPN11 | SOCS3 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12403768 |
| PTPN11 | ROS1 | Two-hybrid | BioGRID | 11266449 |
| PTPN11 | PRLR | Affinity Capture-Western | BioGRID | 10991949 |
| PTPN11 | FRS2 | - | HPRD | 9632781 |11447289 |
| - | HPRD,BioGRID | 9632781 | ||
| PTPN11 | KLRC1 | - | HPRD | 9485206 |
| PTPN11 | PILRA | - | HPRD | 10660620 |
| Affinity Capture-Western | BioGRID | 10903717 | ||
| PTPN11 | CAV1 | - | HPRD,BioGRID | 12176037 |
| caveolin-1 interacts with SH-PTP2. | BIND | 12176037 | ||
| PTPN11 | EPHA2 | Affinity Capture-Western | BioGRID | 10655584 |
| PTPN11 | SIGLEC11 | - | HPRD,BioGRID | 11986327 |
| PTPN11 | SHC1 | - | HPRD | 10650943 |
| PTPN11 | TIE1 | - | HPRD | 10949653 |
| PTPN11 | C6orf25 | - | HPRD,BioGRID | 11544253 |
| PTPN11 | CRKL | - | HPRD,BioGRID | 9344843 |
| PTPN11 | LEPR | - | HPRD | 11018044 |
| PTPN11 | BDKRB2 | - | HPRD | 12177051 |
| PTPN11 | PIK3R1 | Affinity Capture-Western | BioGRID | 9918857 |
| PTPN11 | PTK2B | - | HPRD,BioGRID | 10880513 |
| PTPN11 | STAT5B | Biochemical Activity; Reconstituted Complex | BioGRID | 10617656 |
| PTPN11 | CEACAM1 | - | HPRD,BioGRID | 9867848 |12108545 |
| PTPN11 | GAB3 | - | HPRD,BioGRID | 11739737 |
| PTPN11 | CSF2RB | - | HPRD,BioGRID | 9162089 |
| PTPN11 | FLT1 | Flt-1 interacts with the amino terminal SH2 domain of SHP-2. | BIND | 9600074 |
| PTPN11 | BCR | Phosphorylated p210bcr-abl interacts with phosphorylated Syp. This interaction was modeled on a demonstrated interaction between human p210bcr-abl and mouse Syp. | BIND | 8195176 |
| - | HPRD | 12115002 | ||
| PTPN11 | IFNAR1 | - | HPRD | 9029147 |
| PTPN11 | IRS1 | - | HPRD,BioGRID | 8505282 |9756938 |
| PTPN11 | PAG1 | - | HPRD | 10790433 |
| PTPN11 | CTLA4 | - | HPRD,BioGRID | 8638161 |
| PTPN11 | NEDD9 | - | HPRD | 8879209 |
| PTPN11 | FRS3 | - | HPRD | 11432792 |
| PTPN11 | LILRB4 | - | HPRD | 9422771 |
| Protein-peptide | BioGRID | 9973385 | ||
| PTPN11 | EGFR | - | HPRD,BioGRID | 7673163 |
| PTPN11 | BCR | Phosphorylated p210bcr-abl interacts with phosphorylated Syp. This interaction was modeled on a demonstrated interaction between human p210bcr-abl and mouse Syp. | BIND | 8195176 |
| - | HPRD | 12115002 | ||
| PTPN11 | GHR | - | HPRD,BioGRID | 10976913 |
| PTPN11 | SIGLEC7 | - | HPRD | 10499918 |
| PTPN11 | GRB2 | Affinity Capture-Western; Far Western; Reconstituted Complex | BioGRID | 8041791 |8702859 |8995399 |9362449 |9632781 |9824671 |10080542 |10212213 |10747947 |
| - | HPRD | 8041791 |8702859 |12531430 | ||
| Grb2 interacts with Syp via Syp SH2 domains. | BIND | 7523381 |8195176 | ||
| PTPN11 | CSF3R | - | HPRD,BioGRID | 9824671 |
| PTPN11 | KIT | - | HPRD,BioGRID | 7523381 |9528781 |
| Syp interacts with c-Kit via its SH2 domain. | BIND | 7523381 | ||
| PTPN11 | IL6ST | - | HPRD,BioGRID | 10946280 |
| - | HPRD | 9195977 | ||
| PTPN11 | SLAMF1 | - | HPRD,BioGRID | 11806999 |
| CD150 interacts with SHP-2. This interaction was modelled on a demonstrated interaction between human CD150 and monkey SHP-2. | BIND | 11477068 | ||
| PTPN11 | CDH5 | - | HPRD,BioGRID | 10681592 |
| PTPN11 | CTNNB1 | Affinity Capture-Western | BioGRID | 10681592 |
| PTPN11 | FCRL3 | Reconstituted Complex | BioGRID | 12051764 |
| PTPN11 | BCAR1 | Affinity Capture-Western | BioGRID | 9188452 |
| PTPN11 | LILRB4 | - | HPRD | 9422771 |
| Protein-peptide | BioGRID | 9973385 | ||
| PTPN6 | IFNAR1 | - | HPRD | 9029147 |
| - | HPRD | 8524272 |9029147 | ||
| PTPN6 | GRB2 | - | HPRD,BioGRID | 11964172 |
| PTPN6 | HOXA10 | - | HPRD,BioGRID | 12145285 |
| PTPN6 | JAK1 | Biochemical Activity | BioGRID | 7629131 |
| PTPN6 | TNFRSF1A | - | HPRD | 11786908 |
| PTPN6 | PTK2B | - | HPRD,BioGRID | 10521452 |10747947 |
| PTPN6 | FCGR2B | - | HPRD | 7716523 |
| PTPN6 | TYK2 | - | HPRD,BioGRID | 7629131 |8780698 |
| PTPN6 | FCRL3 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12051764 |
| PTPN6 | BCR | - | HPRD,BioGRID | 9211920 |
| PTPN6 | C6orf25 | - | HPRD,BioGRID | 11544253 |
| PTPN6 | PILRA | - | HPRD,BioGRID | 10660620 |10903717 |
| PTPN6 | SIRPA | - | HPRD,BioGRID | 10660565 |
| - | HPRD | 10660565 |14662855 | ||
| PTPN6 | PECAM1 | - | HPRD,BioGRID | 9774457 |
| PTPN6 | NOS1 | - | HPRD,BioGRID | 11511520 |
| PTPN6 | KLRC1 | - | HPRD | 9485206 |
| PTPN6 | PIK3R1 | Two-hybrid | BioGRID | 11160222 |
| - | HPRD | 11337495 | ||
| PTPN6 | LCK | - | HPRD | 8114715 |11294838 |
| Biochemical Activity; in vitro; in vivo | BioGRID | 8114715 |10617656 |11294838 | ||
| PTPN6 | CD72 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 9590210 |11114375 |12882840 |
| - | HPRD | 9590210 |9740800 | ||
| PTPN6 | CD5 | - | HPRD,BioGRID | 10082557 |
| PTPN6 | SIGLEC12 | - | HPRD | 11328818 |
| PTPN6 | LAIR1 | - | HPRD | 9285412 |10764762 |11160222|11160222 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 9285412 |10660620 |10764762 |10903717 |11160222 | ||
| PTPN6 | CBL | - | HPRD,BioGRID | 12176909 |
| PTPN6 | PAG1 | - | HPRD,BioGRID | 10790433 |
| PTPN6 | SLAMF6 | - | HPRD,BioGRID | 11489943 |
| PTPN6 | CSF2RB | - | HPRD,BioGRID | 8246974 |
| PTPN6 | PIK3R1 | Two-hybrid | BioGRID | 11160222 |
| - | HPRD | 11337495 | ||
| PTPN6 | JAK2 | - | HPRD,BioGRID | 8943354 |
| PTPN6 | SSTR2 | - | HPRD,BioGRID | 9305905 |11920268 |
| PTPN6 | PTPRC | - | HPRD | 9368621 |10228003 |
| PTPN6 | PRKCD | - | HPRD,BioGRID | 11723252 |
| PTPN6 | BLNK | - | HPRD,BioGRID | 11356834 |
| PTPN6 | STAT5B | - | HPRD,BioGRID | 9211920 |
| PTPN6 | CLEC4A | - | HPRD | 11178971 |
| PTPN6 | EPOR | - | HPRD,BioGRID | 7889566 |
| PTPN6 | SIGLEC11 | - | HPRD,BioGRID | 11986327 |
| PTPN6 | ABL1 | Affinity Capture-Western | BioGRID | 8692915 |
| PTPN6 | CD72 | Affinity Capture-Western; Reconstituted Complex | BioGRID | 9590210 |11114375 |12882840 |
| - | HPRD | 9590210 |9740800 | ||
| PTPN6 | SYK | Affinity Capture-Western; Biochemical Activity | BioGRID | 10072516 |10747947 |
| - | HPRD | 10072516 |11356834 | ||
| PTPN6 | CD22 | - | HPRD,BioGRID | 9890995 |
| PTPN6 | TREML1 | - | HPRD,BioGRID | 12393607 |
| PTPN6 | LILRB4 | - | HPRD,BioGRID | 9151699 |9973385 |
| PTPN6 | INSR | - | HPRD,BioGRID | 7512963 |
| PTPN6 | CXCR4 | - | HPRD,BioGRID | 10506573 |
| PTPN6 | CD300LF | - | HPRD | 14662855 |15184070 |15549731 |
| PTPN6 | SYK | Affinity Capture-Western; Biochemical Activity | BioGRID | 10072516 |10747947 |
| - | HPRD | 10072516 |11356834 | ||
| PTPN6 | LAIR1 | - | HPRD | 9285412 |10764762 |11160222|11160222 |
| Affinity Capture-Western; Reconstituted Complex; Two-hybrid | BioGRID | 9285412 |10660620 |10764762 |10903717 |11160222 | ||
| PTPN6 | VAV1 | - | HPRD,BioGRID | 8632004 |
| PTPN6 | CEACAM1 | - | HPRD | 9867848 |
| PTPN6 | ZAP70 | - | HPRD,BioGRID | 8638162 |10458769 |
| PTPN6 | IL4R | - | HPRD,BioGRID | 11714803 |
| PTPN6 | LCP2 | - | HPRD,BioGRID | 8760799 |9765283 |
| PTPN6 | SIRPA | - | HPRD,BioGRID | 10660565 |
| - | HPRD | 10660565 |14662855 | ||
| PTPN6 | CAV1 | - | HPRD,BioGRID | 12176037 |
| caveolin-1 interacts with PTP-1C. | BIND | 12176037 | ||
| PTPN6 | GAB2 | - | HPRD,BioGRID | 11895767 |
| PTPN6 | KIT | - | HPRD,BioGRID | 7684496 |9528781 |
| PTPN6 | CD33 | - | HPRD,BioGRID | 10206955 |
| PTPN6 | LIFR | - | HPRD,BioGRID | 10800945 |
| PTPN6 | IRS4 | - | HPRD | 12774026 |
| PTPN6 | IFNAR1 | - | HPRD | 9029147 |
| - | HPRD | 8524272 |9029147 | ||
| PTPN6 | IL6ST | - | HPRD,BioGRID | 10800945 |
| PTPN6 | CTNND1 | - | HPRD,BioGRID | 10835420 |
| PTPN6 | CAV1 | - | HPRD,BioGRID | 12176037 |
| caveolin-1 interacts with PTP-1C. | BIND | 12176037 | ||
| PTPN6 | LCK | - | HPRD | 8114715 |11294838 |
| Biochemical Activity; in vitro; in vivo | BioGRID | 8114715 |10617656 |11294838 | ||
| PTPN6 | GHR | - | HPRD | 9632636 |
| PTPN6 | SOS1 | Affinity Capture-Western | BioGRID | 8632004 |
| PTPN6 | DOK1 | - | HPRD | 10585470 |
| PTPN6 | EGFR | - | HPRD,BioGRID | 9733788 |
| PTPN6 | LYN | - | HPRD,BioGRID | 10574931 |
| PTPN6 | ROS1 | - | HPRD,BioGRID | 11266449 |
| PTPN6 | LILRB2 | - | HPRD,BioGRID | 9531263 |9842885 |
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