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Protein-protein interaction for DLX1
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene DLX1
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| DLX1 | SMAD4 | - | HPRD,BioGRID | 14671321 |
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| SMAD4 | SPTBN1 | - | HPRD | 12543979 |
| SMAD4 | GLI3 | - | HPRD | 9843199 |
| SMAD4 | HOXA9 | - | HPRD,BioGRID | 11042172 |
| SMAD4 | ATF2 | - | HPRD,BioGRID | 10085140 |
| SMAD4 | ZNF423 | - | HPRD,BioGRID | 10660046 |
| SMAD4 | SMAD3 | - | HPRD | 9311995|9732876 |
| Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| Smad4 interacts with Smad3. | BIND | 15761153 | ||
| Affinity Capture-Western | BioGRID | 9311995 |9892009 |10531362 |11114293 |12419246 |12794086 |15084259 | ||
| SMAD4 | UBE2I | Two-hybrid | BioGRID | 16189514 |
| SMAD4 | STK11IP | - | HPRD,BioGRID | 11741830 |
| SMAD4 | DVL1 | Reconstituted Complex | BioGRID | 12650946 |
| SMAD4 | MDM4 | Reconstituted Complex | BioGRID | 12483531 |
| SMAD4 | HOXC8 | - | HPRD,BioGRID | 10224145 |
| SMAD4 | MEF2A | - | HPRD | 11160896 |
| SMAD4 | EID2 | - | HPRD,BioGRID | 14612439 |
| SMAD4 | AKT1 | Affinity Capture-Western | BioGRID | 16362038 |
| SMAD4 | FOXO3 | - | HPRD,BioGRID | 15084259 |
| FoxO3 interacts with Smad4. | BIND | 15084259 | ||
| SMAD4 | CITED1 | - | HPRD,BioGRID | 9707553 |
| SMAD4 | MED15 | - | HPRD | 12167862 |
| SMAD4 | DCP1A | - | HPRD,BioGRID | 11836524 |
| SMAD4 | EP300 | Affinity Capture-Western | BioGRID | 10887155 |
| p300 interacts with Smad4 fragment. p300 interacting with full-length Smad4 could not be demonstrated in vitro. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad4 fragment. | BIND | 9679056 | ||
| SMAD4 | SMAD7 | Phenotypic Suppression | BioGRID | 9892009 |
| SMAD4 | SMAD3 | - | HPRD | 9311995|9732876 |
| Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| Smad4 interacts with Smad3. | BIND | 15761153 | ||
| Affinity Capture-Western | BioGRID | 9311995 |9892009 |10531362 |11114293 |12419246 |12794086 |15084259 | ||
| SMAD4 | RBL1 | - | HPRD,BioGRID | 12150994 |
| SMAD4 | ACVR1B | - | HPRD | 9892009 |
| SMAD4 | SKIL | Smad4 interacts with SnoN. This interaction was modeled on a demonstrated interaction between human Smad4 and SnoN from an unspecified species. | BIND | 15761153 |
| - | HPRD,BioGRID | 10531062 | ||
| SMAD4 | JUND | - | HPRD | 10220381 |
| SMAD4 | CEBPB | CEBPB (C/EBP-beta) interacts with SMAD4. This interaction was modeled on a demonstrated interaction between CEBPB and SMAD4, both from unspecified species. | BIND | 12202226 |
| - | HPRD,BioGRID | 12524424 | ||
| SMAD4 | EWSR1 | Two-hybrid | BioGRID | 16189514 |
| SMAD4 | PIAS3 | - | HPRD,BioGRID | 14691252 |
| SMAD4 | SMAD9 | Affinity Capture-Western; Two-hybrid | BioGRID | 10583507 |16189514 |
| SMAD4 | PARD3B | Reconstituted Complex | BioGRID | 12650946 |
| SMAD4 | TGFBR2 | T-beta-RII phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RII from an unspecified species and human hMAD-4. | BIND | 8774881 |
| SMAD4 | FOXO3 | - | HPRD,BioGRID | 15084259 |
| FoxO3 interacts with Smad4. | BIND | 15084259 | ||
| SMAD4 | SNW1 | Phenotypic Enhancement; Two-hybrid | BioGRID | 11278756 |
| SMAD4 | SKI | - | HPRD,BioGRID | 12419246 |12857746 |
| Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species. | BIND | 15761153 | ||
| c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski. | BIND | 10575014 | ||
| SMAD4 | SMAD3 | - | HPRD | 9311995|9732876 |
| Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| Smad4 interacts with Smad3. | BIND | 15761153 | ||
| Affinity Capture-Western | BioGRID | 9311995 |9892009 |10531362 |11114293 |12419246 |12794086 |15084259 | ||
| SMAD4 | SMAD1 | - | HPRD | 10400705 |11700304 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 10531362 |11700304 |12874272 | ||
| Smad4 interacts with Smad1. | BIND | 15761153 | ||
| SMAD4 | SUMO1 | SMAD4 is sumoylated. | BIND | 15592428 |
| SMAD4 | SP1 | - | HPRD | 11432852 |
| SMAD4 | MAX | - | HPRD,BioGRID | 12551947 |
| SMAD4 | EP300 | Affinity Capture-Western | BioGRID | 10887155 |
| p300 interacts with Smad4 fragment. p300 interacting with full-length Smad4 could not be demonstrated in vitro. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad4 fragment. | BIND | 9679056 | ||
| SMAD4 | SMAD2 | - | HPRD,BioGRID | 11274206 |
| Smad4 interacts with Smad2. | BIND | 15761153 | ||
| Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| SMAD4 | JUN | - | HPRD | 10220381 |
| SMAD4 | SNIP1 | - | HPRD,BioGRID | 10887155 |
| SMAD4 | FOXO4 | - | HPRD,BioGRID | 15084259 |
| FoxO4 interacts with Smad4. | BIND | 15084259 | ||
| SMAD4 | JUNB | - | HPRD,BioGRID | 10220381 |
| SMAD4 | SMAD1 | - | HPRD | 10400705 |11700304 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 10531362 |11700304 |12874272 | ||
| Smad4 interacts with Smad1. | BIND | 15761153 | ||
| SMAD4 | BTRC | - | HPRD,BioGRID | 14988407 |
| SMAD4 | SMAD5 | Affinity Capture-Western | BioGRID | 10531362 |
| SMAD4 | SMAD3 | - | HPRD | 9311995|9732876 |
| Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| Smad4 interacts with Smad3. | BIND | 15761153 | ||
| Affinity Capture-Western | BioGRID | 9311995 |9892009 |10531362 |11114293 |12419246 |12794086 |15084259 | ||
| SMAD4 | TGFBR1 | T-beta-RI phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-4. | BIND | 8774881 |
| Co-fractionation | BioGRID | 11102446 | ||
| SMAD4 | CAMK2G | - | HPRD,BioGRID | 11027280 |
| SMAD4 | TGFBR1 | T-beta-RI phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-4. | BIND | 8774881 |
| Co-fractionation | BioGRID | 11102446 | ||
| SMAD4 | STUB1 | Smad4 interacts with CHIP. This interaction was modeled on a demonstrated interaction between Smad1 and CHIP, both from an unspecified species. | BIND | 15708501 |
| SMAD4 | SKI | - | HPRD,BioGRID | 12419246 |12857746 |
| Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species. | BIND | 15761153 | ||
| c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski. | BIND | 10575014 | ||
| SMAD4 | KPNB1 | Affinity Capture-Western | BioGRID | 10846168 |
| SMAD4 | CTNNB1 | - | HPRD,BioGRID | 12000714 |
| SMAD4 | CEBPD | Affinity Capture-Western; Reconstituted Complex | BioGRID | 12524424 |
| SMAD4 | SMAD2 | - | HPRD,BioGRID | 11274206 |
| Smad4 interacts with Smad2. | BIND | 15761153 | ||
| Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| SMAD4 | FOXO4 | - | HPRD,BioGRID | 15084259 |
| FoxO4 interacts with Smad4. | BIND | 15084259 | ||
| SMAD4 | FOXO1 | FoxO1 interacts with Smad4. | BIND | 15084259 |
| - | HPRD,BioGRID | 15084259 | ||
| SMAD4 | CEBPB | CEBPB (C/EBP-beta) interacts with SMAD4. This interaction was modeled on a demonstrated interaction between CEBPB and SMAD4, both from unspecified species. | BIND | 12202226 |
| - | HPRD,BioGRID | 12524424 | ||
| SMAD4 | PIAS4 | Affinity Capture-Western | BioGRID | 12815042 |
| SMAD4 | TSSK3 | SMAD4 interacts with STK22C. This interaction was modeled on a demonstrated interaction between human SMAD4 and mouse STK22C. | BIND | 15761153 |
| SMAD4 | TFE3 | - | HPRD,BioGRID | 10557285 |
| SMAD4 | DACH1 | - | HPRD | 14525983 |
| SMAD4 | TOB1 | - | HPRD,BioGRID | 11163184 |
| SMAD4 | LEF1 | - | HPRD,BioGRID | 10890911 |
| SMAD4 | TGFBRAP1 | - | HPRD,BioGRID | 11278302 |
| SMAD4 | SMAD2 | - | HPRD,BioGRID | 11274206 |
| Smad4 interacts with Smad2. | BIND | 15761153 | ||
| Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species. | BIND | 9311995 | ||
| SMAD4 | SMAD1 | - | HPRD | 10400705 |11700304 |
| Affinity Capture-Western; Co-fractionation | BioGRID | 10531362 |11700304 |12874272 | ||
| Smad4 interacts with Smad1. | BIND | 15761153 | ||
| SMAD4 | SKI | - | HPRD,BioGRID | 12419246 |12857746 |
| Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species. | BIND | 15761153 | ||
| c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski. | BIND | 10575014 | ||
| SMAD4 | TGFB1I1 | ARA55 interacts with Smad4. This interaction was modeled on a demonstrated interaction between human ARA55 and Smad4 from an unspecified species. | BIND | 15561701 |
| SMAD4 | ECSIT | - | HPRD | 14633973 |
| SMAD4 | BRCA1 | BRCA1 interacts with Smad4. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad4 from an unspecified species. | BIND | 15735739 |
| SMAD4 | ZNF521 | - | HPRD | 14630787 |
| SMAD4 | AR | - | HPRD,BioGRID | 12226080 |
| SMAD4 | FOXO1 | FoxO1 interacts with Smad4. | BIND | 15084259 |
| - | HPRD,BioGRID | 15084259 | ||
| SMAD4 | FSTL3 | - | HPRD | 11571638 |
| SMAD4 | COPS5 | - | HPRD,BioGRID | 11818334 |
| SMAD4 | ZNF8 | - | HPRD | 12370310 |
| SMAD4 | SKIL | Smad4 interacts with SnoN. This interaction was modeled on a demonstrated interaction between human Smad4 and SnoN from an unspecified species. | BIND | 15761153 |
| - | HPRD,BioGRID | 10531062 | ||
| SMAD4 | TRIM33 | Smad4 interacts with Ecto. | BIND | 15820681 |
| SMAD4 | UBE2L3 | - | HPRD | 12794086 |
| SMAD4 | CDKN1A | Smad4 binds the distal region of the p21Cip1 promoter. | BIND | 15084259 |
| SMAD4 | FOXH1 | Reconstituted Complex; Two-hybrid | BioGRID | 9288972 |
| SMAD4 | ERBB2IP | - | HPRD,BioGRID | 12650946 |
| SMAD4 | CEBPA | Reconstituted Complex | BioGRID | 12524424 |
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