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Protein-protein interaction for FGFR2
 Nodes,
degree=1 |
 Nodes,
degree=2 |
Protein-protein interaction data for gene FGFR2
| Degree = 1 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| FGFR2 | FGF7 | Reconstituted Complex | BioGRID | 9582367 |
| - | HPRD | 7687739 | ||
| Reconstituted Complex | BioGRID | 9582367 | ||
| - | HPRD | 7687739 | ||
| FGFR2 | FGF1 | - | HPRD | 10618369|11069186 |
| Co-crystal Structure; Reconstituted Complex | BioGRID | 8576175 |10618369 |11069186 | ||
| - | HPRD | 10618369|11069186 | ||
| Co-crystal Structure; Reconstituted Complex | BioGRID | 8576175 |10618369 |11069186 | ||
| FGFR2 | PLCG1 | - | HPRD | 7999363 |
| - | HPRD | 7999363 | ||
| FGFR2 | FGF2 | - | HPRD | 10950949 |
| - | HPRD | 10950949 | ||
| FGFR2 | FGF5 | - | HPRD | 11876253 |
| - | HPRD | 11876253 | ||
| FGFR2 | FGF10 | - | HPRD,BioGRID | 9582367 |
| - | HPRD,BioGRID | 9582367 | ||
| FGFR2 | CACNA1D | - | HPRD | 11292657 |
| - | HPRD | 11292657 | ||
| FGFR2 | FGFR2 | Co-crystal Structure | BioGRID | 11069186 |
| Co-crystal Structure | BioGRID | 11069186 | ||
| FGFR2 | FGF9 | - | HPRD | 8576175 |
| - | HPRD | 8576175 | ||
| Degree = 2 | ||||
|---|---|---|---|---|
| Interactor A | Interactor B | Experimental method | Source | Pubmed |
| FGF7 | DUSP3 | - | HPRD | 1281549 |
| FGF7 | NRP1 | NRP1 (Npn-1) interacts with FGF7. This interaction was modeled on a demonstrated interaction between rat NRP1 and human FGF7. | BIND | 15695515 |
| FGF7 | COL3A1 | - | HPRD,BioGRID | 11973338 |
| FGF7 | COL2A1 | - | HPRD,BioGRID | 11973338 |
| FGF7 | HSPG2 | - | HPRD,BioGRID | 10702276 |
| FGF7 | COL1A1 | in vitro | BioGRID | 11973338 |
| FGF1 | FGFR1 | Co-crystal Structure; Reconstituted Complex | BioGRID | 8576175 |11030354 |
| - | HPRD | 10336501 |11032250 | ||
| FGF1 | CSNK2B | - | HPRD,BioGRID | 12145206 |
| FGF1 | CSNK2A1 | - | HPRD,BioGRID | 12145206 |
| FGF1 | FGFR1 | Co-crystal Structure; Reconstituted Complex | BioGRID | 8576175 |11030354 |
| - | HPRD | 10336501 |11032250 | ||
| FGF1 | CSNK2A2 | - | HPRD,BioGRID | 12145206 |
| FGF1 | NRP1 | NRP1 (Npn-1) interacts with FGF1. This interaction was modeled on a demonstrated interaction between rat NRP1 and human FGF1. | BIND | 15695515 |
| FGF1 | FGFR4 | - | HPRD,BioGRID | 10336501 |10736564 |
| FGF1 | FGFBP1 | - | HPRD,BioGRID | 11509569 |
| FGF1 | SYT1 | - | HPRD,BioGRID | 11432880 |
| FGF1 | FGFR3 | - | HPRD,BioGRID | 10574949 |
| FGF1 | FIBP | - | HPRD,BioGRID | 9806903 |
| FGF1 | HSPA9 | - | HPRD,BioGRID | 10510314 |
| FGF1 | S100A13 | - | HPRD,BioGRID | 9712836 |11432880|11432880 |
| PLCG1 | KDR | Reconstituted Complex | BioGRID | 9398617 |
| PLCG1 | NTRK1 | - | HPRD,BioGRID | 1715690 |
| PLCG1 | PLCG2 | - | HPRD | 8885868 |
| PLCG1 | WAS | Reconstituted Complex | BioGRID | 8805332 |8824280 |
| - | HPRD | 8892607 | ||
| PLCG1 | FGFR1 | An unspecified isoform of FGFR1 interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between FGFR1 from an unspecified species and human PLC-gamma. | BIND | 15117958 |
| Two-hybrid | BioGRID | 9660748 | ||
| PLCG1 | RICS | - | HPRD,BioGRID | 12454018 |
| PLCG1 | RASA1 | Affinity Capture-Western | BioGRID | 9743338 |
| PLCG1 | LCK | - | HPRD | 1500851 |
| PLCG1 | PDGFRB | - | HPRD,BioGRID | 8443409 |
| Autophosphorylated PDGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human PDGFR and PLC-gamma from an unspecified species. | BIND | 8890167 | ||
| Phosphorylated beta-PDGFR interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine PLC-gamma. | BIND | 8388538 | ||
| Beta-PDGFR interacts with PLC-gamma 1. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and PLC-gamma from bovine and unspecified sources. | BIND | 2173144 |7592796 |7689724 |7876130 | ||
| PLCG1 | GHR | Reconstituted Complex | BioGRID | 9632636 |
| PLCG1 | FYN | - | HPRD | 10586033 |
| PLCG1 | PDGFRB | - | HPRD,BioGRID | 8443409 |
| Autophosphorylated PDGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human PDGFR and PLC-gamma from an unspecified species. | BIND | 8890167 | ||
| Phosphorylated beta-PDGFR interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine PLC-gamma. | BIND | 8388538 | ||
| Beta-PDGFR interacts with PLC-gamma 1. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and PLC-gamma from bovine and unspecified sources. | BIND | 2173144 |7592796 |7689724 |7876130 | ||
| PLCG1 | FLT1 | Reconstituted Complex; Two-hybrid | BioGRID | 9398617 |
| Flt-1 interacts with the amino terminal SH2 domain of PLC-gamma. | BIND | 9398617 | ||
| PLCG1 | NTRK2 | Reconstituted Complex; Two-hybrid | BioGRID | 10092678 |12074588 |
| PLCG1 | FLT1 | Reconstituted Complex; Two-hybrid | BioGRID | 9398617 |
| Flt-1 interacts with the amino terminal SH2 domain of PLC-gamma. | BIND | 9398617 | ||
| PLCG1 | TRPC3 | PLCG1 interacts with TRPC3. This interaction was modelled on a demonstrated interaction between rat PLCG1 and human TRPC3. | BIND | 15744307 |
| - | HPRD | 15744307 |15766521 | ||
| PLCG1 | ALK | Affinity Capture-Western | BioGRID | 11888936 |
| - | HPRD | 9174053 | ||
| PLCG1 | SHC1 | Affinity Capture-Western | BioGRID | 8662733 |
| PLCG1 | LAT | - | HPRD,BioGRID | 9729044 |11368773 |
| LAT interacts with an unspecified isoform of PLC-gamma-1. | BIND | 15696170 | ||
| PLCG1 | ABL1 | c-Abl interacts with PLC-gamma1. This interaction was modeled on a demonstrated interaction between human c-Abl and bovine PLCgamma1. | BIND | 1383690 |
| Reconstituted Complex | BioGRID | 10708759 | ||
| PLCG1 | GAB1 | - | HPRD,BioGRID | 8596638 |
| PLCG1 | EEF1A1 | - | HPRD,BioGRID | 11886851 |
| PLCG1 | ITK | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | BioGRID | 10586033 |12163161 |
| - | HPRD | 10586033|12163161 | ||
| PLCG1 | PITPNA | - | HPRD,BioGRID | 7761838 |
| PLCG1 | GAB2 | Reconstituted Complex | BioGRID | 10391903 |
| PLCG1 | WAS | Reconstituted Complex | BioGRID | 8805332 |8824280 |
| - | HPRD | 8892607 | ||
| PLCG1 | KHDRBS1 | - | HPRD,BioGRID | 9743338 |
| PLCG1 | DAB1 | - | HPRD | 15062102 |
| PLCG1 | ZAP70 | - | HPRD,BioGRID | 7629168 |
| PLCG1 | SNAP91 | - | HPRD | 11779129 |
| PLCG1 | CD22 | - | HPRD,BioGRID | 8627166 |
| PLCG1 | USO1 | - | HPRD | 12507498 |
| PLCG1 | MST1R | - | HPRD,BioGRID | 8918464 |
| PLCG1 | RHOA | - | HPRD,BioGRID | 12071848 |
| PLCG1 | PAK1 | - | HPRD,BioGRID | 12085993 |
| PLCG1 | TRPC3 | PLCG1 interacts with TRPC3. This interaction was modelled on a demonstrated interaction between rat PLCG1 and human TRPC3. | BIND | 15744307 |
| - | HPRD | 15744307 |15766521 | ||
| PLCG1 | PKN2 | - | HPRD,BioGRID | 8910519 |
| PLCG1 | GRB2 | - | HPRD,BioGRID | 9281317 |
| PLCG1 | PICALM | - | HPRD,BioGRID | 10926122 |
| PLCG1 | SOS2 | - | HPRD,BioGRID | 10940929 |
| PLCG1 | ITK | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | BioGRID | 10586033 |12163161 |
| - | HPRD | 10586033|12163161 | ||
| PLCG1 | EGFR | - | HPRD,BioGRID | 9207933 |
| EGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human EGFR and bovine PLC-gamma. | BIND | 2173144 |2176151 | ||
| PLCG1 | LIFR | - | HPRD,BioGRID | 7512571 |
| PLCG1 | HCK | - | HPRD | 10586033 |
| PLCG1 | PDGFRA | - | HPRD,BioGRID | 7535778 |
| PLCG1 | FGFR1 | An unspecified isoform of FGFR1 interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between FGFR1 from an unspecified species and human PLC-gamma. | BIND | 15117958 |
| Two-hybrid | BioGRID | 9660748 | ||
| PLCG1 | RHOU | Wrch-1 interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between human Wrch-1 and PLC-gamma from an unspecified species. | BIND | 15556869 |
| PLCG1 | GNB2L1 | - | HPRD,BioGRID | 8290562 |
| PLCG1 | SH3BP2 | - | HPRD,BioGRID | 11390470 |
| PLCG1 | PDGFA | Affinity Capture-Western | BioGRID | 8443409 |
| PLCG1 | CD28 | - | HPRD | 8386518 |
| PLCG1 | ALK | Affinity Capture-Western | BioGRID | 11888936 |
| - | HPRD | 9174053 | ||
| PLCG1 | SHB | Affinity Capture-Western | BioGRID | 10488157 |
| - | HPRD | 12084069 | ||
| PLCG1 | IRS2 | - | HPRD,BioGRID | 9535722 |
| PLCG1 | PLD2 | - | HPRD,BioGRID | 12646582 |
| PLC-gamma1 interacts with PLD2. This interaction was modeled on a demonstrated interaction between PLC-gamma1 from an unspecified species and human PLD2. | BIND | 14744865 | ||
| PLCG1 | NTRK3 | Reconstituted Complex | BioGRID | 10092678 |
| - | HPRD | 7657612 | ||
| PLCG1 | BCR | BCR interacts with PLCgamma1. This interaction was modeled on a demonstrated interaction between BCR from an unspecified source and bovine PLCgamma1. | BIND | 1383690 |
| PLCG1 | SHB | Affinity Capture-Western | BioGRID | 10488157 |
| - | HPRD | 12084069 | ||
| PLCG1 | PECAM1 | - | HPRD,BioGRID | 10350061 |
| PLCG1 | LAT2 | - | HPRD,BioGRID | 12514734 |
| PLCG1 | RET | RET9 phosphorylates PLC-gamma via its amino-terminal SH2 domain. This interaction was modelled on a demonstrated interaction between RET9 from human and PLC-gamma from cow. | BIND | 9047383 |
| - | HPRD,BioGRID | 8628282 | ||
| PLCG1 | KIT | Kit interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between mouse proteins. | BIND | 10022833 |
| - | HPRD,BioGRID | 7536744 | ||
| PLCG1 | PTPRJ | - | HPRD,BioGRID | 11259588 |
| PLCG1 | NTRK3 | Reconstituted Complex | BioGRID | 10092678 |
| - | HPRD | 7657612 | ||
| PLCG1 | LYN | - | HPRD | 10586033 |
| PLCG1 | RET | RET9 phosphorylates PLC-gamma via its amino-terminal SH2 domain. This interaction was modelled on a demonstrated interaction between RET9 from human and PLC-gamma from cow. | BIND | 9047383 |
| - | HPRD,BioGRID | 8628282 | ||
| PLCG1 | CBL | - | HPRD,BioGRID | 9712732 |12061819 |
| PLCG1 | SYK | Affinity Capture-Western | BioGRID | 7831290 |
| - | HPRD | 8885868 | ||
| PLCG1 | PDGFRB | - | HPRD,BioGRID | 8443409 |
| Autophosphorylated PDGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human PDGFR and PLC-gamma from an unspecified species. | BIND | 8890167 | ||
| Phosphorylated beta-PDGFR interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine PLC-gamma. | BIND | 8388538 | ||
| Beta-PDGFR interacts with PLC-gamma 1. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and PLC-gamma from bovine and unspecified sources. | BIND | 2173144 |7592796 |7689724 |7876130 | ||
| PLCG1 | KIT | Kit interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between mouse proteins. | BIND | 10022833 |
| - | HPRD,BioGRID | 7536744 | ||
| PLCG1 | PRKD1 | - | HPRD,BioGRID | 8885868 |
| PLCG1 | BAG3 | - | HPRD,BioGRID | 10980614 |
| PLCG1 | SELE | - | HPRD,BioGRID | 12960351 |
| PLCG1 | LCP2 | - | HPRD,BioGRID | 11390650 |
| PLCG1 | GSN | Reconstituted Complex | BioGRID | 9164868 |
| PLCG1 | SYK | Affinity Capture-Western | BioGRID | 7831290 |
| - | HPRD | 8885868 | ||
| PLCG1 | VAV3 | - | HPRD | 11094073 |
| PLCG1 | TUB | - | HPRD,BioGRID | 10455176 |
| PLCG1 | GIT1 | - | HPRD,BioGRID | 14523024 |
| PLCG1 | TRPM7 | - | HPRD,BioGRID | 11941371 |
| PLCG1 | CTSS | - | HPRD | 9164868 |
| PLCG1 | AGAP2 | - | HPRD | 11823862 |
| PLCG1 | PLD2 | - | HPRD,BioGRID | 12646582 |
| PLC-gamma1 interacts with PLD2. This interaction was modeled on a demonstrated interaction between PLC-gamma1 from an unspecified species and human PLD2. | BIND | 14744865 | ||
| PLCG1 | ERBB2 | - | HPRD,BioGRID | 1676673 |1683701 |
| PLCG1 | TNK1 | - | HPRD,BioGRID | 10873601 |
| PLCG1 | EGFR | - | HPRD,BioGRID | 9207933 |
| EGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human EGFR and bovine PLC-gamma. | BIND | 2173144 |2176151 | ||
| PLCG1 | PTK2 | - | HPRD,BioGRID | 8660853|10430888 |
| PLCG1 | GTF2H1 | - | HPRD | 10467411 |
| PLCG1 | SYN1 | - | HPRD | 10899172 |
| PLCG1 | SYNCRIP | Reconstituted Complex | BioGRID | 9341187 |
| PLCG1 | PDGFRB | - | HPRD,BioGRID | 8443409 |
| Autophosphorylated PDGFR interacts with PLC-gamma. This interaction was modelled on a demonstrated interaction between human PDGFR and PLC-gamma from an unspecified species. | BIND | 8890167 | ||
| Phosphorylated beta-PDGFR interacts with PLC-gamma. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and bovine PLC-gamma. | BIND | 8388538 | ||
| Beta-PDGFR interacts with PLC-gamma 1. This interaction was modeled on a demonstrated interaction between human beta-PDGFR and PLC-gamma from bovine and unspecified sources. | BIND | 2173144 |7592796 |7689724 |7876130 | ||
| PLCG1 | LAT | - | HPRD,BioGRID | 9729044 |11368773 |
| LAT interacts with an unspecified isoform of PLC-gamma-1. | BIND | 15696170 | ||
| PLCG1 | SOS1 | - | HPRD,BioGRID | 10913276 |
| PLCG1 | SH2B3 | Affinity Capture-Western | BioGRID | 8649391 |
| PLCG1 | DGKZ | - | HPRD,BioGRID | 12890670 |
| PLCG1 | SRC | - | HPRD,BioGRID | 7510703 |
| PLCG1 | DOK1 | Reconstituted Complex | BioGRID | 11071635 |
| PLCG1 | DDR1 | - | HPRD | 10783152 |
| PLCG1 | VAV1 | - | HPRD,BioGRID | 9891995 |
| PLCG1 | ABL1 | c-Abl interacts with PLC-gamma1. This interaction was modeled on a demonstrated interaction between human c-Abl and bovine PLCgamma1. | BIND | 1383690 |
| Reconstituted Complex | BioGRID | 10708759 | ||
| PLCG1 | SOCS7 | - | HPRD | 9344857 |
| FGF2 | CSNK2A2 | Reconstituted Complex | BioGRID | 12145206 |
| - | HPRD | 7735329 | ||
| FGF2 | SDC1 | Co-purification | BioGRID | 16982797 |
| FGF2 | PF4 | - | HPRD | 9558385 |
| FGF2 | CD44 | - | HPRD | 7532176 |
| FGF2 | API5 | - | HPRD | 11075807 |
| FGF2 | SDC3 | - | HPRD,BioGRID | 8344959 |
| FGF2 | FGFR4 | - | HPRD | 8530375 |
| FGF2 | GPC3 | - | HPRD,BioGRID | 12478660 |
| FGF2 | VTN | - | HPRD,BioGRID | 11796824 |
| FGF2 | CEP57 | - | HPRD | 12717444 |
| FGF2 | FGFR1 | - | HPRD,BioGRID | 10950949 |11030354 |
| FGF2 | SDC2 | Co-purification | BioGRID | 16982797 |
| FGF2 | NRP1 | NRP1 (Npn-1) interacts with FGF2. This interaction was modeled on a demonstrated interaction between rat NRP1 and human FGF2. | BIND | 15695515 |
| FGF2 | RPL6 | - | HPRD,BioGRID | 9826564 |
| FGF2 | SDC4 | Co-purification | BioGRID | 16982797 |
| FGF2 | CSNK2A2 | Reconstituted Complex | BioGRID | 12145206 |
| - | HPRD | 7735329 | ||
| FGF2 | HSPG2 | - | HPRD | 11847221 |
| FGF2 | RPS19 | - | HPRD,BioGRID | 11716516 |
| FGF2 | CSNK2B | Reconstituted Complex | BioGRID | 12145206 |
| FGF2 | CSNK2A1 | - | HPRD,BioGRID | 12145206 |
| FGF2 | GPC4 | - | HPRD,BioGRID | 11066092 |
| FGF2 | FGFBP1 | - | HPRD,BioGRID | 11509569 |
| FGF2 | CXCL13 | - | HPRD | 11708770 |
| FGF5 | EGF | - | HPRD | 1658709 |
| FGF5 | VEGFA | - | HPRD | 9323936 |
| FGF5 | FGFR1 | - | HPRD,BioGRID | 8386828 |
| FGF5 | TGFA | - | HPRD | 1658709 |
| CACNA1D | STX1A | - | HPRD | 10468580 |
| FGF9 | FGFR3 | - | HPRD,BioGRID | 8576175 |10574949 |
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